Phase I Trial of a Selective c-MET Inhibitor ARQ 197 Incorporating Proof of Mechanism Pharmacodynamic Studies
YAP, Timothy A, OLMOS, David, COLLINS, David, DESOUZA, Nandita M, LEACH, Martin O, SAVAGE, Ronald E, WAGHORNE, Carol, FENG CHAI, GARMEY, Edward, SCHWARTZ, Brian, KAYE, Stan B, DE BONO, Johann S, BRUNETTO, Andre T, TUNARIU, Nina, BARRIUSO, Jorge, RIISNAES, Ruth, POPE, Lorna, CLARK, Jeremy, FUTREAL, Andrew, GERMUSKA, Michael
Published in Journal of clinical oncology (01.04.2011)
Published in Journal of clinical oncology (01.04.2011)
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Patient Selection for Oncology Phase I Trials: A Multi-Institutional Study of Prognostic Factors
OLMOS, David, A'HERN, Roger P, SCHELLENS, Jan H, DEL CONTE, Gianluca, BRUNETTO, Andre T, JEFFRY EVANS, T. R, WILSON, Richard, GALLERANI, Elisa, PLUMMER, Ruth, TABERNERO, Josep, SORIA, Jean-Charles, KAYE, Stan B, MARSONI, Silvia, MORALES, Rafael, GOMEZ-ROCA, Carlos, VERWEIJ, Jaap, VOEST, Emile E, SCHÖFFSKI, Patrick, JOO ERN ANG, PENEL, Nicolas
Published in Journal of clinical oncology (20.03.2012)
Published in Journal of clinical oncology (20.03.2012)
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Dose-response relationship in phase i clinical trials: a European Drug Development Network (EDDN) Collaboration Study
Moreno García, Victor, Olmos, David, Gomez-Roca, Carlos, Cassier, Philippe A, Morales-Barrera, Rafael, Del Conte, Gianluca, Gallerani, Elisa, Brunetto, Andre T, Schöffski, Patrick, Marsoni, Silvia, Schellens, Jan H M, Penel, Nicolas, Voest, Emile, Evans, Jeffrey, Plummer, Ruth, Wilson, Richard H, Soria, Jean Charles, Tabernero, Josep, Verweij, Jaap, Kaye, Stan B
Published in Clinical cancer research (15.11.2014)
Published in Clinical cancer research (15.11.2014)
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EHMT2/G9a as an Epigenetic Target in Pediatric and Adult Brain Tumors
Souza, Barbara Kunzler, Freire, Natalia Hogetop, Jaeger, Mariane, de Farias, Caroline Brunetto, Brunetto, Algemir L, Brunetto, André T, Roesler, Rafael
Published in International journal of molecular sciences (19.10.2021)
Published in International journal of molecular sciences (19.10.2021)
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Possible mechanisms and biomarkers of resistance to vismodegib in SHH medulloblastoma
Roesler, Rafael, de Farias, Caroline Brunetto, Brunetto, André T, Gregianin, Lauro, Jaeger, Mariane, Nör, Carolina, Thomaz, Amanda
Published in Neuro-oncology (Charlottesville, Va.) (01.07.2022)
Published in Neuro-oncology (Charlottesville, Va.) (01.07.2022)
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Cancer Stem Cells and Chemoresistance in Ewing Sarcoma
Dos Santos, Rafael Pereira, Roesler, Rafael, Gregianin, Lauro, Brunetto, André T, da Cunha Jaeger, Mariane, Lunardi Brunetto, Algemir, de Farias, Caroline Brunetto
Published in Current stem cell research & therapy (01.01.2023)
Published in Current stem cell research & therapy (01.01.2023)
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Phase I Study of GSK461364, a Specific and Competitive Polo-like Kinase 1 Inhibitor, in Patients with Advanced Solid Malignancies
OLMOS, David, BARKER, Douglas, SMITH, Deborah A, MURRAY, Sharon C, LAMPKIN, Thomas A, DAR, Mohammed M, WILSON, Richard, DE BONO, Johann S, BLAGDEN, Sarah P, SHARMA, Rohini, BRUNETTO, Andre T, YAP, Timothy A, TAEGTMEYER, Anne B, BARRIUSO, Jorge, MEDANI, Hanine, DEGENHARDT, Yan Y, ALLRED, Alicia J
Published in Clinical cancer research (15.05.2011)
Published in Clinical cancer research (15.05.2011)
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Incidence and risk factors for oral mucositis in pediatric patients receiving chemotherapy
Curra, Marina, Gabriel, Amanda F., Ferreira, Maria Beatriz C., Martins, Marco Antonio T., Brunetto, André T., Gregianin, Lauro J., Martins, Manoela Domingues
Published in Supportive care in cancer (01.11.2021)
Published in Supportive care in cancer (01.11.2021)
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Oncogenic functions of ZEB1 in pediatric solid cancers: interplays with microRNAs and long noncoding RNAs
Fratini, Lívia, Jaeger, Mariane, de Farias, Caroline Brunetto, Brunetto, André T., Brunetto, Algemir L., Shaw, Lisa, Roesler, Rafael
Published in Molecular and cellular biochemistry (01.11.2021)
Published in Molecular and cellular biochemistry (01.11.2021)
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Histone Methyltransferases G9a/Ehmt2 and GLP/Ehmt1 Are Associated with Cell Viability and Poorer Prognosis in Neuroblastoma and Ewing Sarcoma
Souza, Barbara Kunzler, Freire, Natalia Hogetop, Monteiro, Thiago Santos, Herlinger, Alice Laschuk, Jaeger, Mariane, Dalmolin, Matheus G. S., de Farias, Caroline Brunetto, Gregianin, Lauro, Brunetto, André T., Brunetto, Algemir L., Thiele, Carol J., Roesler, Rafael
Published in International journal of molecular sciences (17.10.2023)
Published in International journal of molecular sciences (17.10.2023)
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Neurotrophin Signaling in Medulloblastoma
Thomaz, Amanda, Jaeger, Mariane, Brunetto, Algemir L, Brunetto, André T, Gregianin, Lauro, de Farias, Caroline Brunetto, Ramaswamy, Vijay, Nör, Carolina, Taylor, Michael D, Roesler, Rafael
Published in Cancers (07.09.2020)
Published in Cancers (07.09.2020)
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G9a/EHMT2 is a Potential Prognostic Biomarker and Molecular Target in SHH Medulloblastoma
Souza, Barbara Kunzler, Freire, Natalia Hogetop, Jaeger, Mariane, de Farias, Caroline Brunetto, Brunetto, Algemir L., Brunetto, André T., Roesler, Rafael
Published in Neuromolecular medicine (01.12.2022)
Published in Neuromolecular medicine (01.12.2022)
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ZEB1 is a Subgroup-Specific Marker of Prognosis and Potential Drug Target in Medulloblastoma
Fratini, Livia, Dalmolin, Matheus Gibeke Siqueira, Sinigaglia, Marialva, da Silveira Perla, Alexandre, de Farias, Caroline Brunetto, Brunetto, Algemir L., Brunetto, André T., da Cunha Jaeger, Mariane, Roesler, Rafael
Published in Neuromolecular medicine (01.03.2023)
Published in Neuromolecular medicine (01.03.2023)
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Stemness and Cell Cycle Regulators and Their Modulation by Retinoic Acid in Ewing Sarcoma
Battistella, Maria Eduarda, Freire, Natália Hogetop, Toson, Bruno, Dalmolin, Matheus, Fernandes, Marcelo A C, Tassinari, Isadora D, Jaeger, Mariane, Brunetto, André T, Brunetto, Algemir L, Gregianin, Lauro, de Farias, Caroline Brunetto, Roesler, Rafael
Published in Current Issues in Molecular Biology (01.05.2024)
Published in Current Issues in Molecular Biology (01.05.2024)
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HDAC and MAPK/ERK Inhibitors Cooperate To Reduce Viability and Stemness in Medulloblastoma
da Cunha Jaeger, Mariane, Ghisleni, Eduarda Chiesa, Cardoso, Paula Schoproni, Siniglaglia, Marialva, Falcon, Tiago, Brunetto, André T., Brunetto, Algemir L., de Farias, Caroline Brunetto, Taylor, Michael D., Nör, Carolina, Ramaswamy, Vijay, Roesler, Rafael
Published in Journal of molecular neuroscience (01.06.2020)
Published in Journal of molecular neuroscience (01.06.2020)
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Histone Deacetylase Inhibitors in Pediatric Brain Cancers: Biological Activities and Therapeutic Potential
Perla, Alexandre, Fratini, Lívia, Cardoso, Paula S., Nör, Carolina, Brunetto, André T., Brunetto, Algemir L., de Farias, Caroline Brunetto, Jaeger, Mariane, Roesler, Rafael
Published in Frontiers in cell and developmental biology (10.07.2020)
Published in Frontiers in cell and developmental biology (10.07.2020)
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Gastrin-releasing peptide receptor expression in lung cancer
Mattei, Jane, Achcar, Rosane D, Cano, Carlos H, Macedo, Bruno R, Meurer, Luise, Batlle, Brenda S, Groshong, Steve D, Kulczynski, Jane M, Roesler, Rafael, Dal Lago, Lissandra, Brunetto, Andre T, Schwartsmann, Gilberto
Published in Archives of pathology & laboratory medicine (1976) (01.01.2014)
Published in Archives of pathology & laboratory medicine (1976) (01.01.2014)
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Targeting Histone Deacetylase Activity to Arrest Cell Growth and Promote Neural Differentiation in Ewing Sarcoma
Souza, Bárbara Kunzler, da Costa Lopez, Patrícia Luciana, Menegotto, Pâmela Rossi, Vieira, Igor Araujo, Kersting, Nathalia, Abujamra, Ana Lúcia, Brunetto, André T., Brunetto, Algemir L., Gregianin, Lauro, de Farias, Caroline Brunetto, Thiele, Carol J., Roesler, Rafael
Published in Molecular neurobiology (01.09.2018)
Published in Molecular neurobiology (01.09.2018)
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First-in-human, Pharmacokinetic and Pharmacodynamic Phase I Study of Resminostat, an Oral Histone Deacetylase Inhibitor, in Patients with Advanced Solid Tumors
BRUNETTO, André T, JOO ERN ANG, HAUNS, Bernhard, STROBEL, Vera, HENTSCH, Bernd, DE BONO, Johann S, LAI, Rohit, OLMOS, David, MOLIFE, L. Rhoda, KRISTELEIT, Rebecca, PARKER, Ann, CASAMAYOR, Isabel, OLALEYE, Muyibat, MAIS, Anna
Published in Clinical cancer research (01.10.2013)
Published in Clinical cancer research (01.10.2013)
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