Universal LC-MS method for minimized carryover in a discovery bioanalytical setting
Williams, John S, Donahue, Stephanie H, Gao, Hong, Brummel, Christopher L
Published in Bioanalysis (01.05.2012)
Published in Bioanalysis (01.05.2012)
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Altering Metabolic Profiles of Drugs by Precision Deuteration 2: Discovery of a Deuterated Analog of Ivacaftor with Differentiated Pharmacokinetics for Clinical Development
Harbeson, Scott L, Morgan, Adam J, Liu, Julie F, Aslanian, Ara M, Nguyen, Sophia, Bridson, Gary W, Brummel, Christopher L, Wu, Lijun, Tung, Roger D, Pilja, Lana, Braman, Virginia, Uttamsingh, Vinita
Published in The Journal of pharmacology and experimental therapeutics (01.08.2017)
Published in The Journal of pharmacology and experimental therapeutics (01.08.2017)
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Evaluating LC–MS/MS To Measure Accumulation of Compounds within Bacteria
Iyer, Ramkumar, Ye, Zhengqi, Ferrari, Annette, Duncan, Leonard, Tanudra, M. Angela, Tsao, Hong, Wang, Tiansheng, Gao, Hong, Brummel, Christopher L., Erwin, Alice L.
Published in ACS infectious diseases (14.09.2018)
Published in ACS infectious diseases (14.09.2018)
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In Vitro and In Vivo Isotope Effects with Hepatitis C Protease Inhibitors: Enhanced Plasma Exposure of Deuterated Telaprevir versus Telaprevir in Rats
Maltais, François, Jung, Young Chun, Chen, Minzhang, Tanoury, Jerry, Perni, Robert B, Mani, Nagraj, Laitinen, Leena, Huang, Hui, Liao, Shengkai, Gao, Hongying, Tsao, Hong, Block, Eric, Ma, Chien, Shawgo, Rebecca S, Town, Christopher, Brummel, Christopher L, Howe, David, Pazhanisamy, S, Raybuck, Scott, Namchuk, Mark, Bennani, Youssef L
Published in Journal of medicinal chemistry (24.12.2009)
Published in Journal of medicinal chemistry (24.12.2009)
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High-throughput screening for glutathione conjugates using stable-isotope labeling and negative electrospray ionization precursor-ion mass spectrometry
Liao, Shengkai, Ewing, Nigel P., Boucher, Brian, Materne, Olivier, Brummel, Christopher L.
Published in Rapid communications in mass spectrometry (30.03.2012)
Published in Rapid communications in mass spectrometry (30.03.2012)
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Method for rapid metabolite profiling of drug candidates in fresh hepatocytes using liquid chromatography coupled with a hybrid quadrupole linear ion trap
Gao, Hongying, Materne, Olivier L., Howe, David L., Brummel, Christopher L.
Published in Rapid communications in mass spectrometry (30.11.2007)
Published in Rapid communications in mass spectrometry (30.11.2007)
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Bioanalytical solutions to acetonitrile shortages
Gao, Hong, Williams, John, Carrier, Scott, Brummel, Christopher L
Published in Bioanalysis (01.09.2010)
Published in Bioanalysis (01.09.2010)
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Biochemical Analysis of the Modular Enzyme Inosine 5′-Monophosphate Dehydrogenase
Nimmesgern, Elmar, Black, James, Futer, Olga, Fulghum, John R., Chambers, Stephen P., Brummel, Christopher L., Raybuck, Scott A., Sintchak, Michael D.
Published in Protein expression and purification (01.11.1999)
Published in Protein expression and purification (01.11.1999)
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Kinetic mechanism and ATP-binding site reactivity of p38γ MAP kinase
Fox, Ted, Fitzgibbon, Matthew J, Fleming, Mark A, Hsiao, Hsun-Mei, Brummel, Christopher L, Su, Michael S-S
Published in FEBS letters (19.11.1999)
Published in FEBS letters (19.11.1999)
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Discovery of VX-509 (Decernotinib): A Potent and Selective Janus Kinase 3 Inhibitor for the Treatment of Autoimmune Diseases
Farmer, Luc J, Ledeboer, Mark W, Hoock, Thomas, Arnost, Michael J, Bethiel, Randy S, Bennani, Youssef L, Black, James J, Brummel, Christopher L, Chakilam, Ananthsrinivas, Dorsch, Warren A, Fan, Bin, Cochran, John E, Halas, Summer, Harrington, Edmund M, Hogan, James K, Howe, David, Huang, Hui, Jacobs, Dylan H, Laitinen, Leena M, Liao, Shengkai, Mahajan, Sudipta, Marone, Valerie, Martinez-Botella, Gabriel, McCarthy, Pamela, Messersmith, David, Namchuk, Mark, Oh, Luke, Penney, Marina S, Pierce, Albert C, Raybuck, Scott A, Rugg, Arthur, Salituro, Francesco G, Saxena, Kumkum, Shannon, Dean, Shlyakter, Dina, Swenson, Lora, Tian, Shi-Kai, Town, Christopher, Wang, Jian, Wang, Tiansheng, Wannamaker, M. Woods, Winquist, Raymond J, Zuccola, Harmon J
Published in Journal of medicinal chemistry (24.09.2015)
Published in Journal of medicinal chemistry (24.09.2015)
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