Strategies to Obtain Diverse and Specific Human Monoclonal Antibodies From Transgenic Animals
Brüggemann, Marianne, Osborn, Michael J, Ma, Biao, Buelow, Roland
Published in Transplantation (01.08.2017)
Published in Transplantation (01.08.2017)
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Human antibody expression in transgenic rats: Comparison of chimeric IgH loci with human VH, D and JH but bearing different rat C-gene regions
Ma, Biao, Osborn, Michael J., Avis, Suzanne, Ouisse, Laure-Hélène, Ménoret, Séverine, Anegon, Ignacio, Buelow, Roland, Brüggemann, Marianne
Published in Journal of immunological methods (31.12.2013)
Published in Journal of immunological methods (31.12.2013)
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The two-domain hypothesis in Beckwith–Wiedemann syndrome: autonomous imprinting of the telomeric domain of the distal chromosome 7 cluster
Cerrato, Flavia, Sparago, Angela, Matteo, Ines Di, Zou, Xiangang, Dean, Wendy, Sasaki, Hiroyuki, Smith, Paul, Genesio, Rita, Bruggemann, Marianne, Reik, Wolf, Riccio, Andrea
Published in Human molecular genetics (15.02.2005)
Published in Human molecular genetics (15.02.2005)
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Multispecific Antibody Development Platform Based on Human Heavy Chain Antibodies
Clarke, Starlynn C, Ma, Biao, Trinklein, Nathan D, Schellenberger, Ute, Osborn, Michael J, Ouisse, Laure-Hélène, Boudreau, Andrew, Davison, Laura M, Harris, Katherine E, Ugamraj, Harshad S, Balasubramani, Aarti, Dang, Kevin H, Jorgensen, Brett, Ogana, Heather Anne N, Pham, Duy T, Pratap, Payal P, Sankaran, Preethi, Anegon, Ignacio, van Schooten, Wim C, Brüggemann, Marianne, Buelow, Roland, Force Aldred, Shelley
Published in Frontiers in immunology (07.01.2019)
Published in Frontiers in immunology (07.01.2019)
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Sequence-Based Discovery Demonstrates That Fixed Light Chain Human Transgenic Rats Produce a Diverse Repertoire of Antigen-Specific Antibodies
Harris, Katherine E, Aldred, Shelley Force, Davison, Laura M, Ogana, Heather Anne N, Boudreau, Andrew, Brüggemann, Marianne, Osborn, Michael, Ma, Biao, Buelow, Benjamin, Clarke, Starlynn C, Dang, Kevin H, Iyer, Suhasini, Jorgensen, Brett, Pham, Duy T, Pratap, Payal P, Rangaswamy, Udaya S, Schellenberger, Ute, van Schooten, Wim C, Ugamraj, Harshad S, Vafa, Omid, Buelow, Roland, Trinklein, Nathan D
Published in Frontiers in immunology (24.04.2018)
Published in Frontiers in immunology (24.04.2018)
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Characterization of immunoglobulin heavy chain knockout rats
Ménoret, Séverine, Iscache, Anne-L, Tesson, Laurent, Rémy, Séverine, Usal, Claire, Osborn, Michel J, Cost, Gregory J, Brüggemann, Marianne, Buelow, Roland, Anegon, Ignacio
Published in European journal of immunology (01.10.2010)
Published in European journal of immunology (01.10.2010)
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Heavy chain-only antibodies are spontaneously produced in light chain-deficient mice
Zou, Xiangang, Osborn, Michael J, Bolland, Daniel J, Smith, Jennifer A, Corcos, Daniel, Hamon, Maureen, Oxley, David, Hutchings, Amanda, Morgan, Geoff, Santos, Fatima, Kilshaw, Peter J, Taussig, Michael J, Corcoran, Anne E, Brüggemann, Marianne
Published in The Journal of experimental medicine (24.12.2007)
Published in The Journal of experimental medicine (24.12.2007)
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Expression of a Dromedary Heavy Chain-Only Antibody and B Cell Development in the Mouse
Zou, Xiangang, Smith, Jennifer A, Nguyen, Viet Khong, Ren, Liming, Luyten, Kattie, Muyldermans, Serge, Bruggemann, Marianne
Published in The Journal of immunology (1950) (15.09.2005)
Published in The Journal of immunology (1950) (15.09.2005)
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Immunoglobulin aggregation leading to Russell body formation is prevented by the antibody light chain
Corcos, Daniel, Osborn, Michael J., Matheson, Louise S., Santos, Fatima, Zou, Xiangang, Smith, Jennifer A., Morgan, Geoff, Hutchings, Amanda, Hamon, Maureen, Oxley, David, Brüggemann, Marianne
Published in Blood (14.01.2010)
Published in Blood (14.01.2010)
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TRANSGENIC NON-HUMAN ANIMALS PRODUCING MODIFIED HEAVY CHAIN-ONLY ANTIBODIES
OSBORN MICHAEL, VANSCHOOTEN WIM, TRINKLEIN NATHAN, FORCE ALDRED SHELLEY, BRUGGEMANN MARIANNE
Year of Publication 21.03.2023
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Year of Publication 21.03.2023
Patent
Antigen-specific single B cell sorting and expression-cloning from immunoglobulin humanized rats: a rapid and versatile method for the generation of high affinity and discriminative human monoclonal antibodies
Ouisse, Laure-Hélène, Gautreau-Rolland, Laetitia, Devilder, Marie-Claire, Osborn, Michael, Moyon, Melinda, Visentin, Jonathan, Halary, Frank, Bruggemann, Marianne, Buelow, Roland, Anegon, Ignacio, Saulquin, Xavier
Published in BMC biotechnology (09.01.2017)
Published in BMC biotechnology (09.01.2017)
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Abstract LB-090: Sequence-based discovery of fully human anti-CD3 and anti-PDL1 single domain antibodies using novel transgenic rats
Trinklein, Nathan, Force Aldred, Shelley, Schellenberger, Ute, Harris, Kat, Clarke, Starlynn, Dang, Kevin, Pham, Duy, Bruggemann, Marianne, vanSchooten, Wim
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Light chain-deficient mice produce novel multimeric heavy-chain-only IgA by faulty class switching
Matheson, Louise S., Osborn, Michael J., Smith, Jennifer A., Corcos, Daniel, Hamon, Maureen, Chaouaf, Rima, Coadwell, John, Morgan, Geoff, Oxley, David, Brüggemann, Marianne
Published in International immunology (01.08.2009)
Published in International immunology (01.08.2009)
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변형된 중쇄-단독 항체를 생산하는 형질전환 비-인간 동물
OSBORN MICHAEL, VANSCHOOTEN WIM, TRINKLEIN NATHAN, FORCE ALDRED SHELLEY, BRUGGEMANN MARIANNE
Year of Publication 15.05.2019
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Year of Publication 15.05.2019
Patent
Block in development at the pre-B-II to immature B cell stage in mice without Ig kappa and Ig lambda light chain
Zou, Xiangang, Piper, Tony A, Smith, Jennifer A, Allen, Nicholas D, Xian, Jian, Brüggemann, Marianne
Published in The Journal of immunology (1950) (01.02.2003)
Published in The Journal of immunology (1950) (01.02.2003)
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Selection of a human anti-progesterone antibody fragment from a transgenic mouse library by ARM ribosome display
He, Mingyue, Menges, Margit, Groves, Maria A.T, Corps, Elaine, Liu, Hong, Brüggemann, Marianne, Taussig, Michael J
Published in Journal of immunological methods (10.12.1999)
Published in Journal of immunological methods (10.12.1999)
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