Single-cell RNA-sequencing of peripheral blood mononuclear cells reveals widespread, context-specific gene expression regulation upon pathogenic exposure
Oelen, Roy, de Vries, Dylan H., Brugge, Harm, Gordon, M. Grace, Vochteloo, Martijn, Ye, Chun J., Westra, Harm-Jan, Franke, Lude, van der Wijst, Monique G. P.
Published in Nature communications (07.06.2022)
Published in Nature communications (07.06.2022)
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Improving the diagnostic yield of exome- sequencing by predicting gene–phenotype associations using large-scale gene expression analysis
Deelen, Patrick, van Dam, Sipko, Herkert, Johanna C., Karjalainen, Juha M., Brugge, Harm, Abbott, Kristin M., van Diemen, Cleo C., van der Zwaag, Paul A., Gerkes, Erica H., Zonneveld-Huijssoon, Evelien, Boer-Bergsma, Jelkje J., Folkertsma, Pytrik, Gillett, Tessa, van der Velde, K. Joeri, Kanninga, Roan, van den Akker, Peter C., Jan, Sabrina Z., Hoorntje, Edgar T., te Rijdt, Wouter P., Vos, Yvonne J., Jongbloed, Jan D. H., van Ravenswaaij-Arts, Conny M. A., Sinke, Richard, Sikkema-Raddatz, Birgit, Kerstjens-Frederikse, Wilhelmina S., Swertz, Morris A., Franke, Lude
Published in Nature communications (28.06.2019)
Published in Nature communications (28.06.2019)
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An integrative approach for building personalized gene regulatory networks for precision medicine
van der Wijst, Monique G P, de Vries, Dylan H, Brugge, Harm, Westra, Harm-Jan, Franke, Lude
Published in Genome medicine (19.12.2018)
Published in Genome medicine (19.12.2018)
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Deconvolution of bulk blood eQTL effects into immune cell subpopulations
Aguirre-Gamboa, Raúl, de Klein, Niek, di Tommaso, Jennifer, Claringbould, Annique, van der Wijst, Monique Gp, de Vries, Dylan, Brugge, Harm, Oelen, Roy, Võsa, Urmo, Zorro, Maria M, Chu, Xiaojin, Bakker, Olivier B, Borek, Zuzanna, Ricaño-Ponce, Isis, Deelen, Patrick, Xu, Cheng-Jiang, Swertz, Morris, Jonkers, Iris, Withoff, Sebo, Joosten, Irma, Sanna, Serena, Kumar, Vinod, Koenen, Hans J P M, Joosten, Leo A B, Netea, Mihai G, Wijmenga, Cisca, Franke, Lude, Li, Yang
Published in BMC bioinformatics (12.06.2020)
Published in BMC bioinformatics (12.06.2020)
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Integrating GWAS with bulk and single-cell RNA-sequencing reveals a role for LY86 in the anti-Candida host response
de Vries, Dylan H, Matzaraki, Vasiliki, Bakker, Olivier B, Brugge, Harm, Westra, Harm-Jan, Netea, Mihai G, Franke, Lude, Kumar, Vinod, van der Wijst, Monique G P
Published in PLoS pathogens (01.04.2020)
Published in PLoS pathogens (01.04.2020)
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Predicted efficacy of a pharmacogenetic passport for inflammatory bowel disease
Bangma, Amber, Voskuil, Michiel D., Uniken Venema, Werna T. C., Brugge, Harm, Hu, Shixian, Lanting, Pauline, Franke, Lude, Dijkstra, Gerard, Festen, Eleonora A. M., Weersma, Rinse K.
Published in Alimentary pharmacology & therapeutics (01.06.2020)
Published in Alimentary pharmacology & therapeutics (01.06.2020)
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Improving the diagnostic yield of exome-sequencing, by predicting gene-phenotype associations using large-scale gene expression analysis
Deelen, Patrick, Sipko Van Dam, Herkert, Johanna C, Karjalainen, Juha M, Brugge, Harm, Abbott, Kristin M, Van Diemen, Cleo C, Paul A Van Der Zwaag, Gerkes, Erica H, Folkertsma, Pytrik, Gillett, Tessa, K Joeri Van Der Velde, Roan Kanninga, Van Den Akker, Peter, Jan, Sabrina Z, Hoorntje, Edgar T, Te Rijdt, Wouter P, Vos, Yvonne J, Jongbloed, Jan D H, Conny M A Van Ravenswaaij-Arts, Sinke, Richard, Sikkema-Raddatz, Birgit, Kerstjens-Frederikse, Wilhelmina S, Swertz, Morris A, Franke, Lude
Published in bioRxiv (11.09.2018)
Published in bioRxiv (11.09.2018)
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