Discovery of Tricyclic Indoles That Potently Inhibit Mcl‑1 Using Fragment-Based Methods and Structure-Based Design
Burke, Jason P, Bian, Zhiguo, Shaw, Subrata, Zhao, Bin, Goodwin, Craig M, Belmar, Johannes, Browning, Carrie F, Vigil, Dominico, Friberg, Anders, Camper, DeMarco V, Rossanese, Olivia W, Lee, Taekyu, Olejniczak, Edward T, Fesik, Stephen W
Published in Journal of medicinal chemistry (14.05.2015)
Published in Journal of medicinal chemistry (14.05.2015)
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Discovery and biological characterization of potent myeloid cell leukemia‐1 inhibitors
Lee, Taekyu, Bian, Zhiguo, Zhao, Bin, Hogdal, Leah J., Sensintaffar, John L., Goodwin, Craig M., Belmar, Johannes, Shaw, Subrata, Tarr, James C., Veerasamy, Nagarathanam, Matulis, Shannon M., Koss, Brian, Fischer, Melissa A., Arnold, Allison L., Camper, DeMarco V., Browning, Carrie F., Rossanese, Olivia W., Budhraja, Amit, Opferman, Joseph, Boise, Lawrence H., Savona, Michael R., Letai, Anthony, Olejniczak, Edward T., Fesik, Stephen W.
Published in FEBS letters (01.01.2017)
Published in FEBS letters (01.01.2017)
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Discovery of Quinazolines That Activate SOS1-Mediated Nucleotide Exchange on RAS
Abbott, Jason R, Patel, Pratiq A, Howes, Jennifer E, Akan, Denis T, Kennedy, J. Phillip, Burns, Michael C, Browning, Carrie F, Sun, Qi, Rossanese, Olivia W, Phan, Jason, Waterson, Alex G, Fesik, Stephen W
Published in ACS medicinal chemistry letters (13.09.2018)
Published in ACS medicinal chemistry letters (13.09.2018)
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Abstract 3551: Discovery of orally bioavailable novel Mcl-1 inhibitors that exhibit selective anti-proliferative activity in Mcl-1 sensitive cancer cell lines
Lee, Taekyu, Bian, Zhiguo, Belmar, Johannes, Shaw, Subrata, Tarr, James C., Zhao, Bin, Pelz, Nick, Camper, DeMarco, Goodwin, Craig M., Arnold, Allison L., Sensintaffar, John L., Browning, Carrie F., Rossanese, Olivia W., Olejniczak, Edward T., Fesik, Stephen W.
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Identification and Optimization of Anthranilic Acid Based Inhibitors of Replication ProteinA
Patrone, James D., Pelz, Nicholas F., Bates, Brittney S., Souza-Fagundes, Elaine M., Vangamudi, Bhavatarini, Camper, Demarco V., Kuznetsov, Alexey G., Browning, Carrie F., Feldkamp, Michael D., Frank, Andreas O., Gilston, Benjamin A., Olejniczak, Edward T., Rossanese, Olivia W., Waterson, Alex G., Chazin, Walter J., Fesik, Stephen W.
Published in ChemMedChem (19.04.2016)
Published in ChemMedChem (19.04.2016)
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Identification and Optimization of Anthranilic Acid Based Inhibitors of Replication Protein A
Patrone, James D., Pelz, Nicholas F., Bates, Brittney S., Souza-Fagundes, Elaine M., Vangamudi, Bhavatarini, Camper, Demarco V., Kuznetsov, Alexey G., Browning, Carrie F., Feldkamp, Michael D., Frank, Andreas O., Gilston, Benjamin A., Olejniczak, Edward T., Rossanese, Olivia W., Waterson, Alex G., Chazin, Walter J., Fesik, Stephen W.
Published in ChemMedChem (19.04.2016)
Published in ChemMedChem (19.04.2016)
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Four and a half LIM protein 1: a partner for KCNA5 in human atrium
Yang, Zhenjiang, Browning, Carrie F., Hallaq, Haifa, Yermalitskaya, Liudmila, Esker, Jan, Hall, Matthew R., Link, Andrew J., Ham, Amy-Joan L., McGrath, Meagan J., Mitchell, Christina A., Murray, Katherine T.
Published in Cardiovascular research (01.06.2008)
Published in Cardiovascular research (01.06.2008)
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Discovery and biological characterization of potent myeloid cell leukemia-1 inhibitors
Lee, Taekyu, Bian, Zhiguo, Zhao, Bin, Hogdal, Leah J., Sensintaffar, John L., Goodwin, Craig M., Belmar, Johannes, Shaw, Subrata, Tarr, James C., Veerasamy, Nagarathanam, Matulis, Shannon M., Koss, Brian, Fischer, Melissa A., Arnold, Allison L., Camper, DeMarco V., Browning, Carrie F., Rossanese, Olivia W., Budhraja, Amit, Opferman, Joseph, Boise, Lawrence H., Savona, Michael R., Letai, Anthony, Olejniczak, Edward T., Fesik, Stephen W.
Published in FEBS letters (19.12.2016)
Published in FEBS letters (19.12.2016)
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