Decreased Metallation and Activity in Subsets of Mutant Superoxide Dismutases Associated with Familial Amyotrophic Lateral Sclerosis
Hayward, Lawrence J, Rodriguez, Jorge A, Kim, Ji W, Tiwari, Ashutosh, Goto, Joy J, Cabelli, Diane E, Valentine, Joan Selverstone, Brown, Jr, Robert H
Published in The Journal of biological chemistry (03.05.2002)
Published in The Journal of biological chemistry (03.05.2002)
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Familial Amyotrophic Lateral Sclerosis-associated Mutations Decrease the Thermal Stability of Distinctly Metallated Species of Human Copper/Zinc Superoxide Dismutase
Rodriguez, Jorge A., Valentine, Joan S., Eggers, Daryl K., Roe, James A., Tiwari, Ashutosh, Brown, Robert H., Hayward, Lawrence J.
Published in The Journal of biological chemistry (03.05.2002)
Published in The Journal of biological chemistry (03.05.2002)
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Amyotrophic Lateral Sclerosis-linked Glutamate Transporter Mutant Has Impaired Glutamate Clearance Capacity
Trotti, Davide, Aoki, Masashi, Pasinelli, Piera, Berger, Urs V., Danbolt, Niels C., Brown, Robert H., Hediger, Matthias A.
Published in The Journal of biological chemistry (05.01.2001)
Published in The Journal of biological chemistry (05.01.2001)
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RNA Interference-Mediated Silencing of Mutant Superoxide Dismutase Rescues Cyclosporin A-Induced Death in Cultured Neuroblastoma Cells
Maxwell, Michele M., Pasinelli, Piera, Kazantsev, Aleksey G., Brown, Robert H., Housman, David E.
Published in Proceedings of the National Academy of Sciences - PNAS (02.03.2004)
Published in Proceedings of the National Academy of Sciences - PNAS (02.03.2004)
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Amyotrophic Lateral Sclerosis-Associated SOD1 Mutant Proteins Bind and Aggregate with Bcl-2 in Spinal Cord Mitochondria
Pasinelli, Piera, Belford, Mary Elizabeth, Lennon, Niall, Bacskai, Brian J, Hyman, Bradley T, Trotti, Davide, Brown, Robert H
Published in Neuron (Cambridge, Mass.) (08.07.2004)
Published in Neuron (Cambridge, Mass.) (08.07.2004)
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Mutant dynactin in motor neuron disease
Puls, Imke, Jonnakuty, Catherine, LaMonte, Bernadette H, Holzbaur, Erika L.F, Tokito, Mariko, Mann, Eric, Floeter, Mary Kay, Bidus, Kimberly, Drayna, Dennis, Oh, Shin J, Brown, Robert H, Ludlow, Christy L, Fischbeck, Kenneth H
Published in Nature genetics (01.04.2003)
Published in Nature genetics (01.04.2003)
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Heterogeneity of Subcellular Localization and Electrophoretic Mobility of Survival Motor Neuron (SMN) Protein in Mammalian Neural Cells and Tissues
Francis, Jonathan W., Sandrock, Alfred W., Bhide, Pradeep G., Vonsattel, Jean-Paul, Brown, Robert H.
Published in Proceedings of the National Academy of Sciences - PNAS (26.05.1998)
Published in Proceedings of the National Academy of Sciences - PNAS (26.05.1998)
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Analysis of FUS gene mutation in familial amyotrophic lateral sclerosis within an Italian cohort
Ticozzi, N, Silani, V, LeClerc, A L, Keagle, P, Gellera, C, Ratti, A, Taroni, F, Kwiatkowski, Jr, T J, McKenna-Yasek, D M, Sapp, P C, Brown, Jr, R H, Landers, J E
Published in Neurology (13.10.2009)
Published in Neurology (13.10.2009)
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Wild-Type Nonneuronal Cells Extend Survival of SOD1 Mutant Motor Neurons in ALS Mice
Clement, A. M., Nguyen, M. D., Roberts, E. A., Garcia, M. L., Boillée, S., Rule, M., McMahon, A. P., Doucette, W., Siwek, D., Ferrante, R. J., Brown, R. H., J. -P. Julien, Goldstein, L. S. B., Cleveland, D. W.
Published in Science (American Association for the Advancement of Science) (03.10.2003)
Published in Science (American Association for the Advancement of Science) (03.10.2003)
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Novel mutation in VCP gene causes atypical amyotrophic lateral sclerosis
González-Pérez, Paloma, Cirulli, Elizabeth T, Drory, Vivian E, Dabby, Ron, Nisipeanu, Puiu, Carasso, Ralph L, Sadeh, Menachem, Fox, Andrew, Festoff, Barry W, Sapp, Peter C, McKenna-Yasek, Diane, Goldstein, David B, Brown, Jr, Robert H, Blumen, Sergiu C
Published in Neurology (27.11.2012)
Published in Neurology (27.11.2012)
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Quantification of reverse transcriptase in ALS and elimination of a novel retroviral candidate
McCormick, A L, Brown, Jr, R H, Cudkowicz, M E, Al-Chalabi, A, Garson, J A
Published in Neurology (22.01.2008)
Published in Neurology (22.01.2008)
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SPTLC1 is mutated in hereditary sensory neuropathy, type I
Bejaoui, K, Wu, Chenyan, Scheffler, MD, Haan, G, Ashby, P, Wu, Lianchan, de Jong, P, Brown Jr, RH
Published in Nature genetics (01.03.2001)
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Published in Nature genetics (01.03.2001)
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Rats Expressing Human Cytosolic Copper-Zinc Superoxide Dismutase Transgenes with Amyotrophic Lateral Sclerosis: Associated Mutations Develop Motor Neuron Disease
Nagai, Makiko, Aoki, Masashi, Miyoshi, Ichiro, Kato, Masaaki, Pasinelli, Piera, Kasai, Noriyuki, Brown, Robert H., Jr, Itoyama, Yasuto
Published in The Journal of neuroscience (01.12.2001)
Published in The Journal of neuroscience (01.12.2001)
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Caspase-1 and -3 Are Sequentially Activated in Motor Neuron Death in Cu,Zn Superoxide Dismutase-Mediated Familial Amyotrophic Lateral Sclerosis
Pasinelli, P, Houseweart, M K, Brown, Jr, R H, Cleveland, D W
Published in Proceedings of the National Academy of Sciences - PNAS (05.12.2000)
Published in Proceedings of the National Academy of Sciences - PNAS (05.12.2000)
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The sarcolemmal proteins dysferlin and caveolin-3 interact in skeletal muscle
MATSUDA, Chie, HAYASHI, Yukiko K, OGAWA, Megumu, AOKI, Masashi, MURAYAMA, Kumiko, NISHINO, Ichizo, NONAKA, Ikuya, ARAHATA, Kiichi, BROWN, Robert H
Published in Human molecular genetics (15.08.2001)
Published in Human molecular genetics (15.08.2001)
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Increased oxidative damage to DNA in ALS patients
Bogdanov, Mikhail, Brown, Robert H, Matson, Wayne, Smart, Ryan, Hayden, Doug, O’Donnell, Heather, Flint Beal, M, Cudkowicz, Merit
Published in Free radical biology & medicine (01.10.2000)
Published in Free radical biology & medicine (01.10.2000)
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Linkage of Familial Amyotrophic Lateral Sclerosis With Frontotemporal Dementia to Chromosome 9q21-q22
Hosler, Betsy A, Siddique, Teepu, Sapp, Peter C, Sailor, Wen, Huang, Michael C, Hossain, Anwar, Daube, Jasper R, Nance, Martha, Fan, Chaohong, Kaplan, Jocelyn, Hung, Wu-Yen, McKenna-Yasek, Diane, Haines, Jonathan L, Pericak-Vance, Margaret A, Horvitz, H. Robert, Brown, Jr, Robert H
Published in JAMA : the journal of the American Medical Association (04.10.2000)
Published in JAMA : the journal of the American Medical Association (04.10.2000)
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Evidence of Increased Oxidative Damage in Both Sporadic and Familial Amyotrophic Lateral Sclerosis
Ferrante, Robert J., Browne, Susan E., Shinobu, Leslie A., Bowling, Allen C., Baik, M. Jay, MacGarvey, Usha, Kowall, Neil W., Brown, Robert H., Beal, M. Flint
Published in Journal of neurochemistry (01.11.1997)
Published in Journal of neurochemistry (01.11.1997)
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