Systematically optimized BCMA/CS1 bispecific CAR-T cells robustly control heterogeneous multiple myeloma
Zah, Eugenia, Nam, Eunwoo, Bhuvan, Vinya, Tran, Uyen, Ji, Brenda Y., Gosliner, Stanley B., Wang, Xiuli, Brown, Christine E., Chen, Yvonne Y.
Published in Nature communications (08.05.2020)
Published in Nature communications (08.05.2020)
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Harnessing and Enhancing Macrophage Phagocytosis for Cancer Therapy
Chen, Siqi, Lai, Seigmund W T, Brown, Christine E, Feng, Mingye
Published in Frontiers in immunology (10.03.2021)
Published in Frontiers in immunology (10.03.2021)
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Dose-dependent thresholds of dexamethasone destabilize CAR T-cell treatment efficacy
Brummer, Alexander B, Yang, Xin, Ma, Eric, Gutova, Margarita, Brown, Christine E, Rockne, Russell C
Published in PLoS computational biology (01.01.2022)
Published in PLoS computational biology (01.01.2022)
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Preclinical Evaluation of CAR T Cell Function: In Vitro and In Vivo Models
Si, Xiaohui, Xiao, Lu, Brown, Christine E, Wang, Dongrui
Published in International journal of molecular sciences (15.03.2022)
Published in International journal of molecular sciences (15.03.2022)
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Outsmarting trogocytosis to boost CAR NK/T cell therapy
Ramezani, Faezeh, Panahi Meymandi, Ahmad Reza, Akbari, Behnia, Tamtaji, Omid Reza, Mirzaei, Hamed, Brown, Christine E, Mirzaei, Hamid Reza
Published in Molecular cancer (16.11.2023)
Published in Molecular cancer (16.11.2023)
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Spatiotemporal analysis of glioma heterogeneity reveals COL1A1 as an actionable target to disrupt tumor progression
Comba, Andrea, Faisal, Syed M., Dunn, Patrick J., Argento, Anna E., Hollon, Todd C., Al-Holou, Wajd N., Varela, Maria Luisa, Zamler, Daniel B., Quass, Gunnar L., Apostolides, Pierre F., Abel, Clifford, Brown, Christine E., Kish, Phillip E., Kahana, Alon, Kleer, Celina G., Motsch, Sebastien, Castro, Maria G., Lowenstein, Pedro R.
Published in Nature communications (24.06.2022)
Published in Nature communications (24.06.2022)
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PGE2-EP2/EP4 signaling elicits mesoCAR T cell immunosuppression in pancreatic cancer
Akbari, Behnia, Soltantoyeh, Tahereh, Shahosseini, Zahra, Jadidi-Niaragh, Farhad, Hadjati, Jamshid, Brown, Christine E, Mirzaei, Hamid Reza
Published in Frontiers in immunology (30.06.2023)
Published in Frontiers in immunology (30.06.2023)
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Glioma IL13Rα2 is associated with mesenchymal signature gene expression and poor patient prognosis
Brown, Christine E, Warden, Charles D, Starr, Renate, Deng, Xutao, Badie, Behnam, Yuan, Yate-Ching, Forman, Stephen J, Barish, Michael E
Published in PloS one (18.10.2013)
Published in PloS one (18.10.2013)
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Structural and practical identifiability of contrast transport models for DCE-MRI
Conte, Martina, Woodall, Ryan T, Gutova, Margarita, Chen, Bihong T, Shiroishi, Mark S, Brown, Christine E, Munson, Jennifer M, Rockne, Russell C
Published in PLoS computational biology (15.05.2024)
Published in PLoS computational biology (15.05.2024)
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Vitamin C, From Supplement to Treatment: A Re-Emerging Adjunct for Cancer Immunotherapy?
Kouakanou, Léonce, Peters, Christian, Brown, Christine E, Kabelitz, Dieter, Wang, Leo D
Published in Frontiers in immunology (12.11.2021)
Published in Frontiers in immunology (12.11.2021)
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Co-stimulatory signaling determines tumor antigen sensitivity and persistence of CAR T cells targeting PSCA+ metastatic prostate cancer
Priceman, Saul J., Gerdts, Ethan A., Tilakawardane, Dileshni, Kennewick, Kelly T., Murad, John P., Park, Anthony K., Jeang, Brook, Yamaguchi, Yukiko, Yang, Xin, Urak, Ryan, Weng, Lihong, Chang, Wen-Chung, Wright, Sarah, Pal, Sumanta, Reiter, Robert E., Wu, Anna M., Brown, Christine E., Forman, Stephen J.
Published in Oncoimmunology (01.02.2018)
Published in Oncoimmunology (01.02.2018)
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A novel berbamine derivative inhibits cell viability and induces apoptosis in cancer stem-like cells of human glioblastoma, via up-regulation of miRNA-4284 and JNK/AP-1 signaling
Yang, Fan, Nam, Sangkil, Brown, Christine E, Zhao, Robin, Starr, Renate, Ma, Yuelong, Xie, Jun, Horne, David A, Malkas, Linda H, Jove, Richard, Hickey, Robert J
Published in PloS one (01.04.2014)
Published in PloS one (01.04.2014)
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Spatial organization of heterogeneous immunotherapy target antigen expression in high-grade glioma
Barish, Michael E., Weng, Lihong, Awabdeh, Dina, Zhai, Yubo, Starr, Renate, D'Apuzzo, Massimo, Rockne, Russell C., Li, Haiqing, Badie, Behnam, Forman, Stephen J., Brown, Christine E.
Published in Neoplasia (New York, N.Y.) (01.08.2022)
Published in Neoplasia (New York, N.Y.) (01.08.2022)
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Neural stem cell-mediated enzyme/prodrug therapy for glioma: preclinical studies
Aboody, Karen S, Najbauer, Joseph, Metz, Marianne Z, D'Apuzzo, Massimo, Gutova, Margarita, Annala, Alexander J, Synold, Timothy W, Couture, Larry A, Blanchard, Suzette, Moats, Rex A, Garcia, Elizabeth, Aramburo, Soraya, Valenzuela, Valerie V, Frank, Richard T, Barish, Michael E, Brown, Christine E, Kim, Seung U, Badie, Behnam, Portnow, Jana
Published in Science translational medicine (08.05.2013)
Published in Science translational medicine (08.05.2013)
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Data driven model discovery and interpretation for CAR T-cell killing using sparse identification and latent variables
Brummer, Alexander B, Xella, Agata, Woodall, Ryan, Adhikarla, Vikram, Cho, Heyrim, Gutova, Margarita, Brown, Christine E, Rockne, Russell C
Published in Frontiers in immunology (15.05.2023)
Published in Frontiers in immunology (15.05.2023)
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Targeting JAK1/STAT3 signaling suppresses tumor progression and metastasis in a peritoneal model of human ovarian cancer
Wen, Wei, Liang, Wei, Wu, Jun, Kowolik, Claudia M, Buettner, Ralf, Scuto, Anna, Hsieh, Meng-Yin, Hong, Hao, Brown, Christine E, Forman, Stephen J, Horne, David, Morgan, Robert, Wakabayashi, Mark, Dellinger, Thanh H, Han, Ernest S, Yim, John H, Jove, Richard
Published in Molecular cancer therapeutics (01.12.2014)
Published in Molecular cancer therapeutics (01.12.2014)
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Genome-wide profiling identified a set of miRNAs that are differentially expressed in glioblastoma stem cells and normal neural stem cells
Lang, Ming-Fei, Yang, Su, Zhao, Chunnian, Sun, Guoqiang, Murai, Kiyohito, Wu, Xiwei, Wang, Jinhui, Gao, Hanlin, Brown, Christine E, Liu, Xiaoxuan, Zhou, Jiehua, Peng, Ling, Rossi, John J, Shi, Yanhong
Published in PloS one (30.04.2012)
Published in PloS one (30.04.2012)
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Targeting Wnt signaling for improved glioma immunotherapy
Gutova, Margarita, Hibbard, Jonathan C, Ma, Eric, Natri, Heini M, Adhikarla, Vikram, Chimge, Nyam-Osor, Qiu, Runxiang, Nguyen, Cu, Melendez, Elizabeth, Aguilar, Brenda, Starr, Renate, Yin, Holly, Rockne, Russel C, Ono, Masaya, Banovich, Nicholas E, Yuan, Yate-Ching, Brown, Christine E, Kahn, Michael
Published in Frontiers in immunology (21.02.2024)
Published in Frontiers in immunology (21.02.2024)
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The future of cancer immunotherapy for brain tumors: a collaborative workshop
Brown, Christine E, Bucktrout, Samantha, Butterfield, Lisa H, Futer, Olga, Galanis, Evanthia, Hormigo, Adilia, Lim, Michael, Okada, Hideho, Prins, Robert, Marr, Sara Siebel, Tanner, Kirk
Published in Journal of translational medicine (23.05.2022)
Published in Journal of translational medicine (23.05.2022)
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