Synthesis and Conformational Analysis of Fluorinated Uridine Analogues Provide Insight into a Neighbouring-Group Participation Mechanism
Michailidou, Freideriki, Lebl, Tomas, Slawin, Alexandra M Z, Sharma, Sunil Vishnuprasadji, Brown, Murray J B, Goss, Rebecca Jane Miriam
Published in Molecules (Basel, Switzerland) (25.11.2020)
Published in Molecules (Basel, Switzerland) (25.11.2020)
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Journal Article
A designed photoenzyme for enantioselective [2+2] cycloadditions
Trimble, Jonathan S., Crawshaw, Rebecca, Hardy, Florence J., Levy, Colin W., Brown, Murray J. B., Fuerst, Douglas E., Heyes, Derren J., Obexer, Richard, Green, Anthony P.
Published in Nature (London) (24.11.2022)
Published in Nature (London) (24.11.2022)
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Journal Article
Biocatalysis: A Pharma Perspective
Adams, Joseph P., Brown, Murray J. B., Diaz‐Rodriguez, Alba, Lloyd, Richard C., Roiban, Gheorghe‐Doru
Published in Advanced synthesis & catalysis (06.06.2019)
Published in Advanced synthesis & catalysis (06.06.2019)
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ATP regeneration by a single polyphosphate kinase powers multigram-scale aldehyde synthesis in vitro
Tavanti, Michele, Hosford, Joseph, Lloyd, Richard C., Brown, Murray J. B.
Published in Green chemistry : an international journal and green chemistry resource : GC (01.01.2021)
Published in Green chemistry : an international journal and green chemistry resource : GC (01.01.2021)
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Journal Article
1-Aryl-3,4-dihydroisoquinoline inhibitors of JNK3
Christopher, John A., Atkinson, Francis L., Bax, Benjamin D., Brown, Murray J.B., Champigny, Aurélie C., Chuang, Tsu Tshen, Jones, Emma J., Mosley, Julie E., Musgrave, James R.
Published in Bioorganic & medicinal chemistry letters (15.04.2009)
Published in Bioorganic & medicinal chemistry letters (15.04.2009)
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Journal Article
Recent Developments and Challenges for the Industrial Implementation of Polyphosphate Kinases
Tavanti, Michele, Hosford, Joseph, Lloyd, Richard C., Brown, Murray J. B.
Published in ChemCatChem (20.08.2021)
Published in ChemCatChem (20.08.2021)
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Journal Article
Assembly of nuclear dimers of PI3K regulatory subunits is regulated by the Cdc42-activated tyrosine kinase ACK
Clayton, Natasha S., Fox, Millie, Vicenté-Garcia, Jose J., Schroeder, Courtney M., Littlewood, Trevor D., Wilde, Jonathon I., Krishnan, Kadalmani, Brown, Murray J.B., Crafter, Claire, Mott, Helen R., Owen, Darerca
Published in The Journal of biological chemistry (01.06.2022)
Published in The Journal of biological chemistry (01.06.2022)
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Journal Article
Efficient Biocatalytic Reductive Aminations by Extending the Imine Reductase Toolbox
Roiban, Gheorghe‐Doru, Kern, Marcelo, Liu, Zhi, Hyslop, Julia, Tey, Pei Lyn, Levine, Matthew S., Jordan, Lydia S., Brown, Kristin K., Hadi, Timin, Ihnken, Leigh Anne F., Brown, Murray J. B.
Published in ChemCatChem (20.12.2017)
Published in ChemCatChem (20.12.2017)
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Journal Article
A designed photoenzyme for enantioselective [2+2] cycloadditions
Trimble, Jonathan S., Crawshaw, Rebecca, Hardy, Florence J., Levy, Colin W., Brown, Murray J. B., Fuerst, Douglas E., Heyes, Derren J., Obexer, Richard, Green, Anthony P.
Published in Nature (London) (24.11.2022)
Published in Nature (London) (24.11.2022)
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Journal Article
Repositioning of a Domain in a Modular Polyketide Synthase to Promote Specific Chain Cleavage
Cortes, Jesus, Kirsten E. H. Wiesmann, Roberts, Gareth A., Murray J. B. Brown, Staunton, James, Leadlay, Peter F.
Published in Science (American Association for the Advancement of Science) (09.06.1995)
Published in Science (American Association for the Advancement of Science) (09.06.1995)
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Journal Article
Corrigendum: Pac13 is a Small Dehydratase that Mediates the Formation of the 3′‐Deoxy Nucleoside of Pacidamycins
Michailidou, Freideriki, Chung, Chun‐wa, Brown, Murray J. B., Naismith, James H., Leavens, William J., Lynn, Sean M., Sharma, Sunil V., Goss, Rebecca J. M.
Published in Angewandte Chemie International Edition (27.07.2020)
Published in Angewandte Chemie International Edition (27.07.2020)
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Journal Article
Pac13 is a Small, Monomeric Dehydratase that Mediates the Formation of the 3′‐Deoxy Nucleoside of Pacidamycins
Michailidou, Freideriki, Chung, Chun‐wa, Brown, Murray J. B., Bent, Andrew F., Naismith, James H., Leavens, William J., Lynn, Sean M., Sharma, Sunil V., Goss, Rebecca J. M.
Published in Angewandte Chemie International Edition (02.10.2017)
Published in Angewandte Chemie International Edition (02.10.2017)
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Journal Article
The identification of potent and selective imidazole-based inhibitors of B-Raf kinase
Takle, Andrew K., Brown, Murray J.B., Davies, Susannah, Dean, David K., Francis, Gerraint, Gaiba, Alessandra, Hird, Alex W., King, Frank D., Lovell, Peter J., Naylor, Antoinette, Reith, Alastair D., Steadman, Jon G., Wilson, David M.
Published in Bioorganic & medicinal chemistry letters (15.01.2006)
Published in Bioorganic & medicinal chemistry letters (15.01.2006)
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Journal Article
Berichtigung: Pac13 is a Small Dehydratase that Mediates the Formation of the 3′‐Deoxy Nucleoside of Pacidamycins
Michailidou, Freideriki, Chung, Chun‐wa, Brown, Murray J. B., Naismith, James H., Leavens, William J., Lynn, Sean M., Sharma, Sunil V., Goss, Rebecca J. M.
Published in Angewandte Chemie (27.07.2020)
Published in Angewandte Chemie (27.07.2020)
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Journal Article
Pac13 is a Small, Monomeric Dehydratase that Mediates the Formation of the 3′‐Deoxy Nucleoside of Pacidamycins
Michailidou, Freideriki, Chung, Chun‐wa, Brown, Murray J. B., Bent, Andrew F., Naismith, James H., Leavens, William J., Lynn, Sean M., Sharma, Sunil V., Goss, Rebecca J. M.
Published in Angewandte Chemie (02.10.2017)
Published in Angewandte Chemie (02.10.2017)
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Journal Article
The identification of clinical candidate SB-480848 : A potent inhibitor of lipoprotein-associated phospholipase A2
BLACKIE, Josie A, BLOOMER, Jackie C, MILLINER, Kevin J, MOORES, Kitty E, PINTO, Ivan L, SMITH, Stephen A, STANSFIELD, Ian G, STANWAY, Steven J, TAYLOR, Maxine A, THEOBALD, Colin J, BROWN, Murray J. B, CHENG, Hung-Yuan, HAMMOND, Beverley, HICKEY, Deirdre M. B, IFE, Robert J, LEACH, Colin A, LEWIS, V. Ann, MACPHEE, Colin H
Published in Bioorganic & medicinal chemistry letters (24.03.2003)
Published in Bioorganic & medicinal chemistry letters (24.03.2003)
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Journal Article
Rational Design of Femtomolar Inhibitors of Isoleucyl tRNA Synthetase from a Binding Model for Pseudomonic Acid-A
Brown, Murray J. B, Mensah, Lucy M, Doyle, Michael L, Broom, Nigel J. P, Osbourne, Neal, Forrest, Andrew K, Richardson, Christine M, O'Hanlon, Peter J, Pope, Andrew J
Published in Biochemistry (Easton) (23.05.2000)
Published in Biochemistry (Easton) (23.05.2000)
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A mutant generated by expression of an engineered DEBS 1 protein from the erythromycin-producing polyketide synthase (PKS) in Streptomyces coelicolor produces the triketide as a lactone, but the major product is the nor-analogue derived from acetate as starter acid
Brown, Murray J. B., Cortes, Jesus, Cutter, Annabel L., Leadlay, Peter F., Staunton, James
Published in Journal of the Chemical Society. Chemical communications (1995)
Published in Journal of the Chemical Society. Chemical communications (1995)
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