Requirement for Ca2+/calmodulin-dependent kinase II in the transition from pressure overload-induced cardiac hypertrophy to heart failure in mice
Ling, Haiyun, Zhang, Tong, Pereira, Laetitia, Means, Christopher Kable, Cheng, Hongqiang, Gu, Yusu, Dalton, Nancy D, Peterson, Kirk L, Chen, Ju, Bers, Donald, Brown, Joan Heller, Heller Brown, Joan
Published in The Journal of clinical investigation (01.05.2009)
Published in The Journal of clinical investigation (01.05.2009)
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SiglecF(HI) Marks Late-Stage Neutrophils of the Infarcted Heart: A Single-Cell Transcriptomic Analysis of Neutrophil Diversification
Calcagno, David M, Zhang, Claire, Toomu, Avinash, Huang, Kenneth, Ninh, Van K, Miyamoto, Shigeki, Aguirre, Aaron D, Fu, Zhenxing, Heller Brown, Joan, King, Kevin R
Published in Journal of the American Heart Association (16.02.2021)
Published in Journal of the American Heart Association (16.02.2021)
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Effects of mango and mint pod-based e-cigarette aerosol inhalation on inflammatory states of the brain, lung, heart, and colon in mice
Moshensky, Alex, Brand, Cameron S, Alhaddad, Hasan, Shin, John, Masso-Silva, Jorge A, Advani, Ira, Gunge, Deepti, Sharma, Aditi, Mehta, Sagar, Jahan, Arya, Nilaad, Sedtavut, Olay, Jarod, Gu, Wanjun, Simonson, Tatum, Almarghalani, Daniyah, Pham, Josephine, Perera, Samantha, Park, Kenneth, Al-Kolla, Rita, Moon, Hoyoung, Das, Soumita, Byun, Min Kwang, Shah, Zahoor, Sari, Youssef, Heller Brown, Joan, Crotty Alexander, Laura E
Published in eLife (12.04.2022)
Published in eLife (12.04.2022)
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Journal Article
Histamine-induced biphasic activation of RhoA allows for persistent RhoA signaling
Zhang, Jason Z, Nguyen, Andy H, Miyamoto, Shigeki, Heller Brown, Joan, McCulloch, Andrew D, Zhang, Jin
Published in PLoS biology (03.09.2020)
Published in PLoS biology (03.09.2020)
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Journal Article
A secretory pathway kinase regulates sarcoplasmic reticulum Ca2+ homeostasis and protects against heart failure
Pollak, Adam J, Liu, Canzhao, Gudlur, Aparna, Mayfield, Joshua E, Dalton, Nancy D, Gu, Yusu, Chen, Ju, Heller Brown, Joan, Hogan, Patrick G, Wiley, Sandra E, Peterson, Kirk L, Dixon, Jack E
Published in eLife (06.12.2018)
Published in eLife (06.12.2018)
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Journal Article
PHLPP-1 Negatively Regulates Akt Activity and Survival in the Heart
Miyamoto, Shigeki, Purcell, Nicole H, Smith, Jeffrey M, Gao, Tianyan, Whittaker, Ross, Huang, Katherine, Castillo, Rene, Glembotski, Chris C, Sussman, Mark A, Newton, Alexandra C, Heller Brown, Joan
Published in Circulation research (20.08.2010)
Published in Circulation research (20.08.2010)
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Journal Article
ATPase Inhibitory Factor-1 Disrupts Mitochondrial Ca2+ Handling and Promotes Pathological Cardiac Hypertrophy through CaMKIIδ
Pavez-Giani, Mario G., Sánchez-Aguilera, Pablo I., Bomer, Nils, Miyamoto, Shigeki, Booij, Harmen G., Giraldo, Paula, Oberdorf-Maass, Silke U., Nijholt, Kirsten T., Yurista, Salva R., Milting, Hendrik, van der Meer, Peter, Boer, Rudolf A. de, Heller Brown, Joan, Sillje, Herman W. H., Westenbrink, B. Daan
Published in International journal of molecular sciences (01.05.2021)
Published in International journal of molecular sciences (01.05.2021)
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Journal Article
Mitochondrial translocation of Nur77 mediates cardiomyocyte apoptosis
ZHAOKANG CHENG, VÖLKERS, Mirko, MASON, Matt, FISCHER, Kimbertee M, KONSTANDIN, Mathias H, ZHANG, Xiao-Kun, BROWN, Joan Heller, SUSSMAN, Mark A, DIN, Shabana, AVITABILE, Daniele, KHAN, Mohsin, GUDE, Natalie, MOHSIN, Sadia, TAO BO, TRUFFA, Silvia, ALVAREZ, Roberto
Published in European heart journal (01.09.2011)
Published in European heart journal (01.09.2011)
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Characterization of lpa2 (Edg4) and lpa1/lpa2 (Edg2/Edg4) Lysophosphatidic Acid Receptor Knockout Mice: Signaling Deficits without Obvious Phenotypic Abnormality Attributable to lpa2
Contos, James J. A., Ishii, Isao, Fukushima, Nobuyuki, Kingsbury, Marcy A., Ye, Xiaoqin, Kawamura, Shuji, Brown, Joan Heller, Chun, Jerold
Published in Molecular and Cellular Biology (01.10.2002)
Published in Molecular and Cellular Biology (01.10.2002)
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Journal Article
Nonequilibrium Reactivation of Na+ Current Drives Early Afterdepolarizations in Mouse Ventricle
Edwards, Andrew G, Grandi, Eleonora, Hake, Johan E, Patel, Sonia, Li, Pan, Miyamoto, Shigeki, Omens, Jeffrey H, Heller Brown, Joan, Bers, Donald M, McCulloch, Andrew D
Published in Circulation. Arrhythmia and electrophysiology (01.12.2014)
Published in Circulation. Arrhythmia and electrophysiology (01.12.2014)
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Journal Article
Increased Sarcoplasmic Reticulum Calcium Leak but Unaltered Contractility by Acute CaMKII Overexpression in Isolated Rabbit Cardiac Myocytes
Kohlhaas, Michael, Zhang, Tong, Seidler, Tim, Zibrova, Darya, Dybkova, Nataliya, Steen, Astrid, Wagner, Stefan, Chen, Lu, Brown, Joan Heller, Bers, Donald M, Maier, Lars S
Published in Circulation research (03.02.2006)
Published in Circulation research (03.02.2006)
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Journal Article
Phosphatidylinositol 3,4,5-triphosphate-dependent Rac exchanger 1 (P-Rex-1), a guanine nucleotide exchange factor for Rac, mediates angiogenic responses to stromal cell-derived factor-1/chemokine stromal cell derived factor-1 (SDF-1/CXCL-12) linked to Rac activation, endothelial cell migration, and in vitro angiogenesis
Carretero-Ortega, Jorge, Walsh, Colin T, Hernández-García, Ricardo, Reyes-Cruz, Guadalupe, Brown, Joan Heller, Vázquez-Prado, José
Published in Molecular pharmacology (01.03.2010)
Published in Molecular pharmacology (01.03.2010)
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Journal Article
Hyperglycemia Acutely Increases Cytosolic Reactive Oxygen Species via O-linked GlcNAcylation and CaMKII Activation in Mouse Ventricular Myocytes
Lu, Shan, Liao, Zhandi, Lu, Xiyuan, Katschinski, Dörthe M., Mercola, Mark, Chen, Ju, Heller Brown, Joan, Molkentin, Jeffery D., Bossuyt, Julie, Bers, Donald M.
Published in Circulation research (08.05.2020)
Published in Circulation research (08.05.2020)
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Journal Article
CaMKII in myocardial hypertrophy and heart failure
Anderson, Mark E, Brown, Joan Heller, Bers, Donald M
Published in Journal of molecular and cellular cardiology (01.10.2011)
Published in Journal of molecular and cellular cardiology (01.10.2011)
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Journal Article
Myocardin-Related Transcription Factor A and Yes-Associated Protein Exert Dual Control in G Protein-Coupled Receptor- and RhoA-Mediated Transcriptional Regulation and Cell Proliferation
Yu, Olivia M., Miyamoto, Shigeki, Brown, Joan Heller
Published in Molecular and cellular biology (01.01.2016)
Published in Molecular and cellular biology (01.01.2016)
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Journal Article
RhoA regulates Drp1 mediated mitochondrial fission through ROCK to protect cardiomyocytes
Brand, Cameron S., Tan, Valerie P., Brown, Joan Heller, Miyamoto, Shigeki
Published in Cellular signalling (01.10.2018)
Published in Cellular signalling (01.10.2018)
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Journal Article
Regulation of the Hippo-YAP pathway by protease-activated receptors (PARs)
Mo, Jung-Soon, Yu, Fa-Xing, Gong, Rui, Brown, Joan Heller, Guan, Kun-Liang
Published in Genes & development (01.10.2012)
Published in Genes & development (01.10.2012)
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Journal Article
Cyclophilin D controls mitochondrial pore–dependent Ca2+ exchange, metabolic flexibility, and propensity for heart failure in mice
Elrod, John W., Wong, Renee, Mishra, Shikha, Vagnozzi, Ronald J., Sakthievel, Bhuvana, Goonasekera, Sanjeewa A., Karch, Jason, Gabel, Scott, Farber, John, Force, Thomas, Heller Brown, Joan, Murphy, Elizabeth, Molkentin, Jeffery D.
Published in The Journal of clinical investigation (01.10.2010)
Published in The Journal of clinical investigation (01.10.2010)
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