High-throughput identification and rational design of synergistic small-molecule pairs for combating and bypassing antibiotic resistance
Wambaugh, Morgan A, Shakya, Viplendra P S, Lewis, Adam J, Mulvey, Matthew A, Brown, Jessica C S
Published in PLoS biology (20.06.2017)
Published in PLoS biology (20.06.2017)
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Unraveling the Biology of a Fungal Meningitis Pathogen Using Chemical Genetics
Brown, Jessica C.S., Nelson, Justin, VanderSluis, Benjamin, Deshpande, Raamesh, Butts, Arielle, Kagan, Sarah, Polacheck, Itzhack, Krysan, Damian J., Myers, Chad L., Madhani, Hiten D.
Published in Cell (20.11.2014)
Published in Cell (20.11.2014)
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Synergistic and antagonistic drug interactions in the treatment of systemic fungal infections
Wambaugh, Morgan A, Denham, Steven T, Ayala, Magali, Brammer, Brianna, Stonhill, Miekan A, Brown, Jessica Cs
Published in eLife (05.05.2020)
Published in eLife (05.05.2020)
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Journal Article
How Environmental Fungi Cause a Range of Clinical Outcomes in Susceptible Hosts
Denham, Steven T., Wambaugh, Morgan A., Brown, Jessica C.S.
Published in Journal of molecular biology (26.07.2019)
Published in Journal of molecular biology (26.07.2019)
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Journal Article
A dissemination-prone morphotype enhances extrapulmonary organ entry by Cryptococcus neoformans
Denham, Steven T., Brammer, Brianna, Chung, Krystal Y., Wambaugh, Morgan A., Bednarek, Joseph M., Guo, Li, Moreau, Christian T., Brown, Jessica C.S.
Published in Cell host & microbe (12.10.2022)
Published in Cell host & microbe (12.10.2022)
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Journal Article
An Evolutionarily Conserved Prion-like Element Converts Wild Fungi from Metabolic Specialists to Generalists
Jarosz, Daniel F., Lancaster, Alex K., Brown, Jessica C.S., Lindquist, Susan
Published in Cell (28.08.2014)
Published in Cell (28.08.2014)
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Journal Article
Distinct pathways of adaptive evolution in Cryptococcus neoformans reveal a mutation in adenylyl cyclase with trade-offs for pathogenicity
Hilbert, Zoë A., Bednarek, Joseph M., Schwiesow, Mara J.W., Chung, Krystal Y., Moreau, Christian T., Brown, Jessica C.S., Elde, Nels C.
Published in Current biology (09.10.2023)
Published in Current biology (09.10.2023)
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Regulated Release of Cryptococcal Polysaccharide Drives Virulence and Suppresses Immune Cell Infiltration into the Central Nervous System
Denham, Steven T, Verma, Surbhi, Reynolds, Raymond C, Worne, Colleen L, Daugherty, Joshua M, Lane, Thomas E, Brown, Jessica C S
Published in Infection and immunity (01.03.2018)
Published in Infection and immunity (01.03.2018)
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Cross-Kingdom Chemical Communication Drives a Heritable, Mutually Beneficial Prion-Based Transformation of Metabolism
Jarosz, Daniel F., Brown, Jessica C.S., Walker, Gordon A., Datta, Manoshi S., Ung, W. Lloyd, Lancaster, Alex K., Rotem, Assaf, Chang, Amelia, Newby, Gregory A., Weitz, David A., Bisson, Linda F., Lindquist, Susan
Published in Cell (28.08.2014)
Published in Cell (28.08.2014)
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Journal Article
Estrogen receptor antagonists are anti-cryptococcal agents that directly bind EF hand proteins and synergize with fluconazole in vivo
Butts, Arielle, Koselny, Kristy, Chabrier-Roselló, Yeissa, Semighini, Camile P, Brown, Jessica C S, Wang, Xuying, Annadurai, Sivakumar, DiDone, Louis, Tabroff, Julie, Childers, Jr, Wayne E, Abou-Gharbia, Magid, Wellington, Melanie, Cardenas, Maria E, Madhani, Hiten D, Heitman, Joseph, Krysan, Damian J
Published in mBio (11.02.2014)
Published in mBio (11.02.2014)
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Journal Article
Phytotherapy as an alternative to conventional antimicrobials: combating microbial resistance
Enioutina, Elena Yu, Teng, Lida, Fateeva, Tatyana V, Brown, Jessica C S, Job, Kathleen M, Bortnikova, Valentina V, Krepkova, Lubov V, Gubarev, Michael I, Sherwin, Catherine M T
Published in Expert review of clinical pharmacology (02.11.2017)
Published in Expert review of clinical pharmacology (02.11.2017)
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Journal Article
Biology and Function of Exo-Polysaccharides from Human Fungal Pathogens
Chung, Krystal Y., Brown, Jessica C. S.
Published in Current clinical microbiology reports (01.03.2020)
Published in Current clinical microbiology reports (01.03.2020)
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