Neuron‐specific deletion of CuZnSOD leads to an advanced sarcopenic phenotype in older mice
Bhaskaran, Shylesh, Pollock, Natalie, Macpherson, Peter, Ahn, Bumsoo, Piekarz, Katarzyna M., Staunton, Caroline A., Brown, Jacob L., Qaisar, Rizwan, Vasilaki, Aphrodite, Richardson, Arlan, McArdle, Anne, Jackson, Malcolm J., Brooks, Susan V., Van Remmen, Holly
Published in Aging cell (01.10.2020)
Published in Aging cell (01.10.2020)
Get full text
Journal Article
Protein imbalance in the development of skeletal muscle wasting in tumour‐bearing mice
Brown, Jacob L., Lee, David E., Rosa‐Caldwell, Megan E., Brown, Lemuel A., Perry, Richard A., Haynie, Wesley S., Huseman, Kendra, Sataranatarajan, Kavithalakshmi, Van Remmen, Holly, Washington, Tyrone A., Wiggs, Michael P., Greene, Nicholas P.
Published in Journal of cachexia, sarcopenia and muscle (01.10.2018)
Published in Journal of cachexia, sarcopenia and muscle (01.10.2018)
Get full text
Journal Article
Development and progression of cancer cachexia: Perspectives from bench to bedside
Lim, Seongkyun, Brown, Jacob L., Washington, Tyrone A., Greene, Nicholas P.
Published in Sports medicine and health science (01.12.2020)
Published in Sports medicine and health science (01.12.2020)
Get full text
Journal Article
Targeting cPLA2 derived lipid hydroperoxides as a potential intervention for sarcopenia
Pharaoh, Gavin, Brown, Jacob L., Sataranatarajan, Kavithalakshmi, Kneis, Parker, Bian, Jan, Ranjit, Rojina, Hadad, Niran, Georgescu, Constantin, Rabinovitch, Peter, Ran, Qitao, Wren, Jonathan D., Freeman, Willard, Kinter, Michael, Richardson, Arlan, Van Remmen, Holly
Published in Scientific reports (18.08.2020)
Published in Scientific reports (18.08.2020)
Get full text
Journal Article
Cancer cachexia in a mouse model of oxidative stress
Brown, Jacob L., Lawrence, Marcus M., Ahn, Bumsoo, Kneis, Parker, Piekarz, Katarzyna M., Qaisar, Rizwan, Ranjit, Rojina, Bian, Jan, Pharaoh, Gavin, Brown, Chase, Peelor, Fredrick F., Kinter, Michael T., Miller, Benjamin F., Richardson, Arlan, Van Remmen, Holly
Published in Journal of cachexia, sarcopenia and muscle (01.12.2020)
Published in Journal of cachexia, sarcopenia and muscle (01.12.2020)
Get full text
Journal Article
Female mice may have exacerbated catabolic signalling response compared to male mice during development and progression of disuse atrophy
Rosa‐Caldwell, Megan E., Lim, Seongkyun, Haynie, Wesley A., Brown, Jacob L., Deaver, John William, Morena Da Silva, Francielly, Jansen, Lisa T., Lee, David E., Wiggs, Michael P., Washington, Tyrone A., Greene, Nicholas P.
Published in Journal of cachexia, sarcopenia and muscle (01.06.2021)
Published in Journal of cachexia, sarcopenia and muscle (01.06.2021)
Get full text
Journal Article
Cancer cachexia-induced muscle atrophy: evidence for alterations in microRNAs important for muscle size
Lee, David E, Brown, Jacob L, Rosa-Caldwell, Megan E, Blackwell, Thomas A, Perry, Jr, Richard A, Brown, Lemuel A, Khatri, Bhuwan, Seo, Dongwon, Bottje, Walter G, Washington, Tyrone A, Wiggs, Michael P, Kong, Byung-Whi, Greene, Nicholas P
Published in Physiological genomics (01.05.2017)
Published in Physiological genomics (01.05.2017)
Get full text
Journal Article
Mitochondrial Function and Protein Turnover in the Diaphragm are Altered in LLC Tumor Model of Cancer Cachexia
Rosa-Caldwell, Megan E, Benson, Conner A, Lee, David E, Brown, Jacob L, Washington, Tyrone A, Greene, Nicholas P, Wiggs, Michael P
Published in International journal of molecular sciences (22.10.2020)
Published in International journal of molecular sciences (22.10.2020)
Get full text
Journal Article
Mitochondrial aberrations during the progression of disuse atrophy differentially affect male and female mice
Rosa‐Caldwell, Megan E., Lim, Seongkyun, Haynie, Wesley S., Brown, Jacob L., Lee, David E., Dunlap, Kirsten R., Jansen, Lisa T., Washington, Tyrone A., Wiggs, Michael P., Greene, Nicholas P.
Published in Journal of cachexia, sarcopenia and muscle (01.12.2021)
Published in Journal of cachexia, sarcopenia and muscle (01.12.2021)
Get full text
Journal Article
Lipid hydroperoxides and oxylipins are mediators of denervation induced muscle atrophy
Brown, Jacob L., Peelor, Fredrick F., Georgescu, Constantin, Wren, Jonathan D., Kinter, Michael, Tyrrell, Victoria J., O'Donnell, Valerie B., Miller, Benjamin F., Van Remmen, Holly
Published in Redox biology (01.11.2022)
Published in Redox biology (01.11.2022)
Get full text
Journal Article
Neuronal deletion of MnSOD in mice leads to demyelination, inflammation and progressive paralysis that mimics phenotypes associated with progressive multiple sclerosis
Bhaskaran, Shylesh, Kumar, Gaurav, Thadathil, Nidheesh, Piekarz, Katarzyna M., Mohammed, Sabira, Lopez, Sergio Dominguez, Qaisar, Rizwan, Walton, Dorothy, Brown, Jacob L., Murphy, Ashley, Smith, Nataliya, Saunders, Debra, Beckstead, Michael J., Plafker, Scott, Lewis, Tommy L., Towner, Rheal, Deepa, Sathyaseelan S., Richardson, Arlan, Axtell, Robert C., Van Remmen, Holly
Published in Redox biology (01.02.2023)
Published in Redox biology (01.02.2023)
Get full text
Journal Article
Regulation of mitochondrial quality following repeated bouts of hindlimb unloading
Rosa-Caldwell, Megan E, Brown, Jacob L, Perry, Richard A, Shimkus, Kevin L, Shirazi-Fard, Yasaman, Brown, Lemuel A, Hogan, Harry A, Fluckey, James D, Washington, Tyrone A, Wiggs, Michael P, Greene, Nicholas P
Published in Applied physiology, nutrition, and metabolism (01.03.2020)
Published in Applied physiology, nutrition, and metabolism (01.03.2020)
Get full text
Journal Article
Moderate physical activity promotes basal hepatic autophagy in diet-induced obese mice
Rosa-Caldwell, Megan E, Lee, David E, Brown, Jacob L, Brown, Lemuel A, Perry, Richard A, Greene, Elizabeth S, Carvallo Chaigneau, Francisco R, Washington, Tyrone A, Greene, Nicholas P
Published in Applied physiology, nutrition, and metabolism (01.02.2017)
Published in Applied physiology, nutrition, and metabolism (01.02.2017)
Get full text
Journal Article
Effects of PGC-1α overexpression on the myogenic response during skeletal muscle regeneration
Washington, Tyrone A., Haynie, Wesley S., Schrems, Eleanor R., Perry, Richard A., Brown, Lemuel A., Williams, Breanna M., Rosa-Caldwell, Megan E., Lee, David E., Brown, Jacob L.
Published in Sports medicine and health science (01.09.2022)
Published in Sports medicine and health science (01.09.2022)
Get full text
Journal Article
Modulation of sarcopenia phenotypes by glutathione peroxidase 4 overexpression in mice
Xu, Hongyang, Czyżowska, Agnieszka, Van Remmen, Holly, Brown, Jacob L.
Published in The Journal of physiology (01.12.2023)
Published in The Journal of physiology (01.12.2023)
Get full text
Journal Article
Cancer‐induced cardiac atrophy adversely affects myocardial redox state and mitochondrial oxidative characteristics
Lee, David E., Brown, Jacob L., Rosa‐Caldwell, Megan E., Perry, Richard A., Brown, Lemuel A., Haynie, Wesley S., Washington, Tyrone A., Wiggs, Michael P., Rajaram, Narasimhan, Greene, Nicholas P.
Published in JCSM rapid communications (01.01.2021)
Published in JCSM rapid communications (01.01.2021)
Get full text
Journal Article
The Akt/mTOR pathway: Data comparing young and aged mice with leucine supplementation at the onset of skeletal muscle regeneration
Perry, Richard A., Brown, Lemuel A., Lee, David E., Brown, Jacob L., Baum, Jamie I., Greene, Nicholas P., Washington, Tyrone A.
Published in Data in brief (01.09.2016)
Published in Data in brief (01.09.2016)
Get full text
Journal Article
Mitochondrial degeneration precedes the development of muscle atrophy in progression of cancer cachexia in tumour‐bearing mice
Brown, Jacob L., Rosa‐Caldwell, Megan E., Lee, David E., Blackwell, Thomas A., Brown, Lemuel A., Perry, Richard A., Haynie, Wesley S., Hardee, Justin P., Carson, James A., Wiggs, Michael P., Washington, Tyrone A., Greene, Nicholas P.
Published in Journal of cachexia, sarcopenia and muscle (01.12.2017)
Published in Journal of cachexia, sarcopenia and muscle (01.12.2017)
Get full text
Journal Article
Senolytic treatment reduces cell senescence and necroptosis in Sod1 knockout mice that is associated with reduced inflammation and hepatocellular carcinoma
Thadathil, Nidheesh, Selvarani, Ramasamy, Mohammed, Sabira, Nicklas, Evan H., Tran, Albert L., Kamal, Maria, Luo, Wenyi, Brown, Jacob L., Lawrence, Marcus M., Borowik, Agnieszka K., Miller, Benjamin F., Remmen, Holly, Richardson, Arlan, Deepa, Sathyaseelan S.
Published in Aging cell (01.08.2022)
Published in Aging cell (01.08.2022)
Get full text
Journal Article