Impact of a five-dimensional framework on R&D productivity at AstraZeneca
Morgan, Paul, Brown, Dean G., Lennard, Simon, Anderton, Mark J., Barrett, J. Carl, Eriksson, Ulf, Fidock, Mark, Hamrén, Bengt, Johnson, Anthony, March, Ruth E., Matcham, James, Mettetal, Jerome, Nicholls, David J., Platz, Stefan, Rees, Steve, Snowden, Michael A., Pangalos, Menelas N.
Published in Nature reviews. Drug discovery (01.03.2018)
Published in Nature reviews. Drug discovery (01.03.2018)
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Journal Article
Synthesis of 7-chloro-2,3-dihydro-2-[1-(pyridinyl)alkyl]-pyridazino[4,5-b]quinoline-1,4,10(5h )-triones as NMDA glycine-site antagonists
BROWN, Dean G, URBANEK, Rebecca A, XIAO, Wenhua, DYROFF, Martin C, LEE, Chi-Ming C, TRIVEDI, Shephali, NEILSON, Kathy L, KEITH, Richard A, BARE, Thomas M, MCLAREN, Frances M, HORCHLER, Carey L, MURPHY, Megan, STEELMAN, Gary B, EMPFIELD, James R, FORST, Janet M, HERZOG, Keith J
Published in Bioorganic & medicinal chemistry letters (20.10.2003)
Published in Bioorganic & medicinal chemistry letters (20.10.2003)
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Journal Article
CETSA beyond Soluble Targets: a Broad Application to Multipass Transmembrane Proteins
Kawatkar, Aarti, Schefter, Michelle, Hermansson, Nils-Olov, Snijder, Arjan, Dekker, Niek, Brown, Dean G, Lundbäck, Thomas, Zhang, Andrew X, Castaldi, M. Paola
Published in ACS chemical biology (20.09.2019)
Published in ACS chemical biology (20.09.2019)
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Journal Article
Substance use disorders in military veterans: prevalence and treatment challenges
Teeters, Jenni B, Lancaster, Cynthia L, Brown, Delisa G, Back, Sudie E
Published in Substance abuse and rehabilitation (01.01.2017)
Published in Substance abuse and rehabilitation (01.01.2017)
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Journal Article
Rural land-use trends in the conterminous United States, 1950-2000
Brown, D.G, Johnson, K.M, Loveland, T.R, Theobald, D.M
Published in Ecological applications (01.12.2005)
Published in Ecological applications (01.12.2005)
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Journal Article
The Origins of Genomic Duplications in Arabidopsis
Vision, Todd J., Brown, Daniel G., Tanksley, Steven D.
Published in Science (American Association for the Advancement of Science) (15.12.2000)
Published in Science (American Association for the Advancement of Science) (15.12.2000)
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Journal Article
Caspase Activation Involves the Formation of the Aposome, a Large (â¼700 kDa) Caspase-activating Complex
Cain, K, Brown, D G, Langlais, C, Cohen, G M
Published in The Journal of biological chemistry (06.08.1999)
Published in The Journal of biological chemistry (06.08.1999)
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Journal Article
Agonists and Antagonists of Protease-Activated Receptor 2 Discovered within a DNA-Encoded Chemical Library Using Mutational Stabilization of the Target
Brown, Dean G., Brown, Giles A., Centrella, Paolo, Certel, Kaan, Cooke, Robert M., Cuozzo, John W., Dekker, Niek, Dumelin, Christoph E., Ferguson, Andrew, Fiez-Vandal, Cédric, Geschwindner, Stefan, Guié, Marie-Aude, Habeshian, Sevan, Keefe, Anthony D., Schlenker, Oliver, Sigel, Eric A., Snijder, Arjan, Soutter, Holly T., Sundström, Linda, Troast, Dawn M., Wiggin, Giselle, Zhang, Jing, Zhang, Ying, Clark, Matthew A.
Published in SLAS discovery (01.06.2018)
Published in SLAS discovery (01.06.2018)
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Journal Article
Regulatory Roles of the N-Terminal Domain Based on Crystal Structures of Human Pyruvate Dehydrogenase Kinase 2 Containing Physiological and Synthetic Ligands
Knoechel, Thorsten R, Tucker, Alec D, Robinson, Colin M, Phillips, Chris, Taylor, Wendy, Bungay, Peter J, Kasten, Shane A, Roche, Thomas E, Brown, David G
Published in Biochemistry (Easton) (17.01.2006)
Published in Biochemistry (Easton) (17.01.2006)
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Journal Article
Classification and boundary vagueness in mapping presettlement forest types
BROWN, DANIEL G.
Published in International journal of geographical information science : IJGIS (01.03.1998)
Published in International journal of geographical information science : IJGIS (01.03.1998)
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Journal Article
Modeling the relationships between land use and land cover on private lands in the Upper Midwest, USA
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