Neurodegeneration-Associated Protein Fragments as Short-Lived Substrates of the N-End Rule Pathway
Brower, Christopher S., Piatkov, Konstantin I., Varshavsky, Alexander
Published in Molecular cell (25.04.2013)
Published in Molecular cell (25.04.2013)
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Glutamine-Specific N-Terminal Amidase, a Component of the N-End Rule Pathway
Wang, Haiqing, Piatkov, Konstantin I., Brower, Christopher S., Varshavsky, Alexander
Published in Molecular cell (26.06.2009)
Published in Molecular cell (26.06.2009)
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Degradation of the Separase-cleaved Rec8, a Meiotic Cohesin Subunit, by the N-end Rule Pathway
Liu, Yu-Jiao, Liu, Chao, Chang, ZeNan, Wadas, Brandon, Brower, Christopher S., Song, Zhen-Hua, Xu, Zhi-Liang, Shang, Yong-Liang, Liu, Wei-Xiao, Wang, Li-Na, Dong, Wen, Varshavsky, Alexander, Hu, Rong-Gui, Li, Wei
Published in The Journal of biological chemistry (01.04.2016)
Published in The Journal of biological chemistry (01.04.2016)
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Liat1, an arginyltransferase-binding protein whose evolution among primates involved changes in the numbers of its 10-residue repeats
Brower, Christopher S., Rosen, Connor E., Jones, Richard H., Wadas, Brandon C., Piatkov, Konstantin I., Varshavsky, Alexander
Published in Proceedings of the National Academy of Sciences - PNAS (18.11.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (18.11.2014)
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BAG6 prevents the aggregation of neurodegeneration-associated fragments of TDP43
Kasu, Yasar Arfat T., Arva, Akshaya, Johnson, Jess, Sajan, Christin, Manzano, Jasmin, Hennes, Andrew, Haynes, Jacy, Brower, Christopher S.
Published in iScience (20.05.2022)
Published in iScience (20.05.2022)
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Arginyltransferase, Its Specificity, Putative Substrates, Bidirectional Promoter, and Splicing-derived Isoforms
Hu, Rong-Gui, Brower, Christopher S., Wang, Haiqing, Davydov, Ilia V., Sheng, Jun, Zhou, Jianmin, Kwon, Yong Tae, Varshavsky, Alexander
Published in The Journal of biological chemistry (27.10.2006)
Published in The Journal of biological chemistry (27.10.2006)
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The N Termini of TAR DNA-Binding Protein 43 (TDP43) C-Terminal Fragments Influence Degradation, Aggregation Propensity, and Morphology
Kasu, Yasar Arfat T., Alemu, Samrawit, Lamari, Angela, Loew, Nicole, Brower, Christopher S.
Published in Molecular and cellular biology (01.10.2018)
Published in Molecular and cellular biology (01.10.2018)
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The Ligand of Ate1 is intrinsically disordered and participates in nucleolar phase separation regulated by Jumonji Domain Containing 6
Arva, Akshaya, Kasu, Yasar Arfat T, Duncan, Jennifer, Alkhatatbeh, Mosleh A, Brower, Christopher S
Published in Proceedings of the National Academy of Sciences - PNAS (05.01.2021)
Published in Proceedings of the National Academy of Sciences - PNAS (05.01.2021)
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Mammalian Mediator Subunit mMED8 is an Elongin BC-Interacting Protein That Can Assemble with Cul2 and Rbx1 to Reconstitute a Ubiquitin Ligase
Brower, Christopher S., Sato, Shigeo, Tomomori-Sato, Chieri, Kamura, Takumi, Pause, Arnim, Stearman, Robert, Klausner, Richard D., Malik, Sohail, Lane, William S., Sorokina, Irina, Roeder, Robert G., Conaway, Joan Weliky, Conaway, Ronald C.
Published in Proceedings of the National Academy of Sciences - PNAS (06.08.2002)
Published in Proceedings of the National Academy of Sciences - PNAS (06.08.2002)
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A Mammalian Homolog of Drosophila melanogaster Transcriptional Coactivator Intersex Is a Subunit of the Mammalian Mediator Complex
Sato, Shigeo, Tomomori-Sato, Chieri, Banks, Charles A.S., Parmely, Tari J., Sorokina, Irina, Brower, Christopher S., Conaway, Ronald C., Conaway, Joan Weliky
Published in The Journal of biological chemistry (12.12.2003)
Published in The Journal of biological chemistry (12.12.2003)
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Journal Article
A Molecular Basis for Stabilization of the von Hippel-Lindau (VHL) Tumor Suppressor Protein by Components of the VHL Ubiquitin Ligase
Kamura, Takumi, Brower, Christopher S., Conaway, Ronald C., Conaway, Joan W.
Published in The Journal of biological chemistry (16.08.2002)
Published in The Journal of biological chemistry (16.08.2002)
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Journal Article
Emerging Roles of Ubiquitin in Transcription Regulation
Conaway, Ronald C., Brower, Christopher S., Conaway, Joan Weliky
Published in Science (American Association for the Advancement of Science) (17.05.2002)
Published in Science (American Association for the Advancement of Science) (17.05.2002)
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Identification of Mammalian Mediator Subunits with Similarities to Yeast Mediator Subunits Srb5, Srb6, Med11, and Rox3
Sato, Shigeo, Tomomori-Sato, Chieri, Banks, Charles A S, Sorokina, Irina, Parmely, Tari J, Kong, Stephanie E, Jin, Jingji, Cai, Yong, Lane, William S, Brower, Christopher S, Conaway, Ronald C, Conaway, Joan Weliky
Published in The Journal of biological chemistry (25.04.2003)
Published in The Journal of biological chemistry (25.04.2003)
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Journal Article
Beta-amyloid induces apoptosis of neuronal cells by inhibition of the Arg/N-end rule pathway proteolytic activity
Kechko, Olga I, Petrushanko, Irina Yu, Brower, Christopher S, Adzhubei, Alexei A, Moskalev, Alexey A, Piatkov, Konstantin I, Mitkevich, Vladimir A, Makarov, Alexander A
Published in Aging (Albany, NY.) (24.08.2019)
Published in Aging (Albany, NY.) (24.08.2019)
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A Mammalian Mediator Subunit that Shares Properties with Saccharomyces cerevisiae Mediator Subunit Cse2
Tomomori-Sato, Chieri, Sato, Shigeo, Parmely, Tari J., Banks, Charles A.S., Sorokina, Irina, Florens, Laurence, Zybailov, Boris, Washburn, Michael P., Brower, Christopher S., Conaway, Ronald C., Conaway, Joan Weliky
Published in The Journal of biological chemistry (13.02.2004)
Published in The Journal of biological chemistry (13.02.2004)
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Both Acute and Consecutive Days of Formoterol Stimulation Influence Myogenic, Mitochondrial, and myomiR Gene Expression in Human Skeletal Muscle Cells
Gordon, Ryan A., Zumbro, Emily L., Guerin, Gena D., Sokoloski, Matthew L., Ben-Ezra, Vic, Brower, Christopher S., Rigby, Rhett B., Duplanty, Anthony A.
Published in Muscles (22.02.2023)
Published in Muscles (22.02.2023)
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