Metabolic dysfunction-associated fatty liver disease increases risk of adverse outcomes in patients with chronic hepatitis B
van Kleef, Laurens A., Choi, Hannah S.J., Brouwer, Willem P., Hansen, Bettina E., Patel, Keyur, de Man, Robert A., Janssen, Harry L.A., de Knegt, Robert J., Sonneveld, Milan J.
Published in JHEP reports (01.10.2021)
Published in JHEP reports (01.10.2021)
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Development of a novel non-invasive biomarker panel for hepatic fibrosis in MASLD
Verschuren, Lars, Mak, Anne Linde, van Koppen, Arianne, Özsezen, Serdar, Difrancesco, Sonia, Caspers, Martien P. M., Snabel, Jessica, van der Meer, David, van Dijk, Anne-Marieke, Rashu, Elias Badal, Nabilou, Puria, Werge, Mikkel Parsberg, van Son, Koen, Kleemann, Robert, Kiliaan, Amanda J., Hazebroek, Eric J., Boonstra, André, Brouwer, Willem P., Doukas, Michail, Gupta, Saurabh, Kluft, Cornelis, Nieuwdorp, Max, Verheij, Joanne, Gluud, Lise Lotte, Holleboom, Adriaan G., Tushuizen, Maarten E., Hanemaaijer, Roeland
Published in Nature communications (29.05.2024)
Published in Nature communications (29.05.2024)
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Unique intrahepatic transcriptomics profiles discriminate the clinical phases of a chronic HBV infection
Hou, Jun, Brouwer, Willem P, Kreefft, Kim, Gama, Lucio, Price, Sarah L, Janssen, Harry L A, French, Pim J, Vanwolleghem, Thomas, Boonstra, Andre
Published in PloS one (29.06.2017)
Published in PloS one (29.06.2017)
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End-of-treatment HBsAg, HBcrAg and HBV RNA predict the risk of off-treatment ALT flares in chronic hepatitis B patients
Brakenhoff, Sylvia M., de Knegt, Robert J., van Campenhout, Margo J.H., van der Eijk, Annemiek A., Brouwer, Willem P., van Bömmel, Florian, Boonstra, André, Hansen, Bettina E., Berg, Thomas, Janssen, Harry L.A., de Man, Robert A., Sonneveld, Milan J.
Published in Journal of microbiology, immunology and infection (01.02.2023)
Published in Journal of microbiology, immunology and infection (01.02.2023)
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Nonalcoholic Steatohepatitis Is Associated With Liver‐Related Outcomes and All‐Cause Mortality in Chronic Hepatitis B
Choi, Hannah S.J., Brouwer, Willem P., Zanjir, Wayel M.R., Man, Robert A., Feld, Jordan J., Hansen, Bettina E., Janssen, Harry L.A., Patel, Keyur
Published in Hepatology (Baltimore, Md.) (01.02.2020)
Published in Hepatology (Baltimore, Md.) (01.02.2020)
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The membrane‐bound O‐acyltransferase domain‐containing 7 variant rs641738 increases inflammation and fibrosis in chronic hepatitis B
Thabet, Khaled, Chan, Henry Lik Yuen, Petta, Salvatore, Mangia, Alessandra, Berg, Thomas, Boonstra, Andre, Brouwer, Willem P., Abate, Maria Lorena, Wong, Vincent Wai‐Sun, Nazmy, Maiiada, Fischer, Janett, Liddle, Christopher, George, Jacob, Eslam, Mohammed
Published in Hepatology (Baltimore, Md.) (01.06.2017)
Published in Hepatology (Baltimore, Md.) (01.06.2017)
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Plasma proteomic signature of fatty liver disease: The Rotterdam Study
Abozaid, Yasir J, Ayada, Ibrahim, van Kleef, Laurens A, Vallerga, Costanza L, Pan, Qiuwei, Brouwer, Willem P, Ikram, M Arfan, Van Meurs, Joyce, de Knegt, Robert J, Ghanbari, Mohsen
Published in Hepatology (Baltimore, Md.) (01.07.2023)
Published in Hepatology (Baltimore, Md.) (01.07.2023)
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Hepatitis B Surface Antigen Levels Can Be Used to Rule Out Cirrhosis in Hepatitis B e Antigen-Positive Chronic Hepatitis B: Results From the SONIC-B Study
Sonneveld, Milan J, Hansen, Bettina E, Brouwer, Willem P, Chan, Henry L-Y, Piratvisuth, Teerha, Jia, Ji-Dong, Zeuzem, Stefan, Chien, Rong-Nan, de Knegt, Robert J, Wat, Cynthia, Pavlovic, Vedran, Gaggar, Anuj, Xie, Qing, Buti, Maria, de Man, Robert A, Janssen, Harry L A
Published in The Journal of infectious diseases (01.06.2022)
Published in The Journal of infectious diseases (01.06.2022)
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Repeated Measurements of Hepatitis B Surface Antigen Identify Carriers of Inactive HBV During Long-term Follow-up
Brouwer, Willem P, Lik-Yuen Chan, Henry, Brunetto, Maurizia R, Martinot-Peignoux, Michelle, Arends, Pauline, Cornberg, Markus, Cherubini, Beatrice, Thompson, Alex J.V, Liaw, Yun-Fan, Marcellin, Patrick, Janssen, Harry L.A, Hansen, Bettina E
Published in Clinical gastroenterology and hepatology (01.10.2016)
Published in Clinical gastroenterology and hepatology (01.10.2016)
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Very low probability of significant liver inflammation in chronic hepatitis B patients with low ALT levels in the absence of liver fibrosis
Sonneveld, Milan J., Brouwer, Willem P., Hansen, Bettina E., Chan, Henry L.‐Y., Piratvisuth, Teerha, Jia, Ji‐Dong, Zeuzem, Stefan, Chien, Rong‐Nan, Choi, Hannah, Knegt, Robert J., Wat, Cynthia, Pavlovic, Vedran, Gaggar, Anuj, Xie, Qing, Buti, Maria, Man, Robert A., Janssen, Harry L.A.
Published in Alimentary pharmacology & therapeutics (01.10.2020)
Published in Alimentary pharmacology & therapeutics (01.10.2020)
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Association Between the Presence of Metabolic Comorbidities and Liver-Related Events in Patients With Chronic Hepatitis B
Patmore, Lesley A., Katwaroe, Warshan K., van der Spek, Daniel, Choi, Hannah S.J., Patel, Keyur, Brakenhoff, Sylvia, van der Meer, Adriaan J., Brouwer, Willem P., van Kleef, Laurens A., de Knegt, Rob J., Hansen, Bettina E., de Man, Rob A., Feld, Jordan J., Janssen, Harry L.A., Sonneveld, Milan J.
Published in Clinical gastroenterology and hepatology (01.11.2023)
Published in Clinical gastroenterology and hepatology (01.11.2023)
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Lifetime prevalence and associated factors of itch with skin conditions: atopic dermatitis, psoriasis and dry skin in individuals aged > 50 years
Bollemeijer, Juliette F, Zheng, Kang J, van der Meer, Alexandra M, Ikram, M Kamran, Kavousi, Maryam, Brouwer, Willem P, Luik, Annemarie I, Chaker, Layal, Xu, Yanning, Gunn, David A, Nijsten, Tamar E C, Pardo, Luba M
Published in Clinical and experimental dermatology (22.08.2024)
Published in Clinical and experimental dermatology (22.08.2024)
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Letter: rates and determinants of significant liver inflammation in chronic hepatitis B virus‐infected patients with low ALT levels in the absence of significant fibrosis—authors' reply
Sonneveld, Milan J., Brouwer, Willem P., Man, Robert A., Janssen, Harry L. A.
Published in Alimentary pharmacology & therapeutics (01.01.2021)
Published in Alimentary pharmacology & therapeutics (01.01.2021)
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Effects of on‐treatment ALT flares on serum HBsAg and HBV RNA in patients with chronic HBV infection
Choi, Hannah S. J., Sonneveld, Milan J., Farag, Mina S., Brouwer, Willem P., Brakenhoff, Sylvia M., Hirode, Grishma, Gehring, Adam J., Man, Rob A., Hansen, Bettina E., Janssen, Harry L. A.
Published in Journal of viral hepatitis (01.12.2021)
Published in Journal of viral hepatitis (01.12.2021)
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CD4+ CXCR5+ T cells in chronic HCV infection produce less IL-21, yet are efficient at supporting B cell responses
Spaan, Michelle, Kreefft, Kim, de Graav, Gretchen N, Brouwer, Willem P, de Knegt, Robert J, ten Kate, Fibo J.W, Baan, Carla C, Vanwolleghem, Thomas, Janssen, Harry L.A, Boonstra, Andre
Published in Journal of hepatology (01.02.2015)
Published in Journal of hepatology (01.02.2015)
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Optimisation of the use of APRI and FIB-4 to rule out cirrhosis in patients with chronic hepatitis B: results from the SONIC-B study
Sonneveld, Milan J, Brouwer, Willem P, Chan, Henry L-Y, Piratvisuth, Teerha, Jia, Ji-Dong, Zeuzem, Stefan, Liaw, Yun-Fan, Hansen, Bettina E, Choi, Hannah, Wat, Cynthia, Pavlovic, Vedran, Gaggar, Anuj, Xie, Qing, Buti, Maria, de Knegt, Robert J, Janssen, Harry L A
Published in The lancet. Gastroenterology & hepatology (01.07.2019)
Published in The lancet. Gastroenterology & hepatology (01.07.2019)
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COVID‐19 in gastroenterology: Where are we now? Current evidence on the impact of COVID‐19 in gastroenterology
Magro, Fernando, Nuzzo, Alexandre, Abreu, Cândida, Libânio, Diogo, Rodriguez‐Lago, Iago, Pawlak, Katarzyna, Hollenbach, Marcus, Brouwer, Willem P., Siau, Keith
Published in UEG Journal (01.09.2021)
Published in UEG Journal (01.09.2021)
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Machine-learning based patient classification using Hepatitis B virus full-length genome quasispecies from Asian and European cohorts
Mueller-Breckenridge, Alan J., Garcia-Alcalde, Fernando, Wildum, Steffen, Smits, Saskia L., de Man, Robert A., van Campenhout, Margo J. H., Brouwer, Willem P., Niu, Jianjun, Young, John A. T., Najera, Isabel, Zhu, Lina, Wu, Daitze, Racek, Tomas, Hundie, Gadissa Bedada, Lin, Yong, Boucher, Charles A., van de Vijver, David, Haagmans, Bart L.
Published in Scientific reports (11.12.2019)
Published in Scientific reports (11.12.2019)
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Dual proteotoxic stress accelerates liver injury via activation of p62‐Nrf2
Kuscuoglu, Deniz, Bewersdorf, Lisa, Wenzel, Kathrin, Gross, Annika, Kobazi Ensari, Gökce, Luo, Yizhao, Kilic, Konrad, Hittatiya, Kanishka, Golob‐Schwarzl, Nicole, Leube, Rudolf E, Preisinger, Christian, George, Jacob, Metwally, Mayada, Eslam, Mohammed, Lampertico, Pietro, Petta, Salvatore, Mangia, Alessandra, Berg, Thomas, Boonstra, Andre, Brouwer, Willem P, Abate, Maria Lorena, Loglio, Alessandro, Sutton, Angela, Nahon, Pierre, Schaefer, Benedikt, Zoller, Heinz, Aigner, Elmar, Trautwein, Christian, Haybaeck, Johannes, Strnad, Pavel
Published in The Journal of pathology (01.05.2021)
Published in The Journal of pathology (01.05.2021)
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