Adiponectin GWAS loci harboring extensive allelic heterogeneity exhibit distinct molecular consequences
Spracklen, Cassandra N, Iyengar, Apoorva K, Vadlamudi, Swarooparani, Raulerson, Chelsea K, Jackson, Anne U, Brotman, Sarah M, Wu, Ying, Cannon, Maren E, Davis, James P, Crain, Aaron T, Currin, Kevin W, Perrin, Hannah J, Narisu, Narisu, Stringham, Heather M, Fuchsberger, Christian, Locke, Adam E, Welch, Ryan P, Kuusisto, Johanna K, Pajukanta, Päivi, Scott, Laura J, Li, Yun, Collins, Francis S, Boehnke, Michael, Laakso, Markku, Mohlke, Karen L
Published in PLoS genetics (11.09.2020)
Published in PLoS genetics (11.09.2020)
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Reference genome and transcriptome informed by the sex chromosome complement of the sample increase ability to detect sex differences in gene expression from RNA-Seq data
Olney, Kimberly C, Brotman, Sarah M, Andrews, Jocelyn P, Valverde-Vesling, Valeria A, Wilson, Melissa A
Published in Biology of sex differences (21.07.2020)
Published in Biology of sex differences (21.07.2020)
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Genetic Diversity on the Human X Chromosome Does Not Support a Strict Pseudoautosomal Boundary
Cotter, Daniel J, Brotman, Sarah M, Wilson Sayres, Melissa A
Published in Genetics (Austin) (01.05.2016)
Published in Genetics (Austin) (01.05.2016)
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Liver eQTL meta-analysis illuminates potential molecular mechanisms of cardiometabolic traits
Broadaway, K. Alaine, Brotman, Sarah M., Rosen, Jonathan D., Currin, Kevin W., Alkhawaja, Abdalla A., Etheridge, Amy S., Wright, Fred, Gallins, Paul, Jima, Dereje, Zhou, Yi-hui, Love, Michael I., Innocenti, Federico, Mohlke, Karen L.
Published in American journal of human genetics (05.09.2024)
Published in American journal of human genetics (05.09.2024)
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Subcutaneous adipose tissue splice quantitative trait loci reveal differences in isoform usage associated with cardiometabolic traits
Brotman, Sarah M., Raulerson, Chelsea K., Vadlamudi, Swarooparani, Currin, Kevin W., Shen, Qiujin, Parsons, Victoria A., Iyengar, Apoorva K., Roman, Tamara S., Furey, Terrence S., Kuusisto, Johanna, Collins, Francis S., Boehnke, Michael, Laakso, Markku, Pajukanta, Päivi, Mohlke, Karen L.
Published in American journal of human genetics (06.01.2022)
Published in American journal of human genetics (06.01.2022)
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ACE2 expression in adipose tissue is associated with cardio-metabolic risk factors and cell type composition—implications for COVID-19
El-Sayed Moustafa, Julia S., Jackson, Anne U., Brotman, Sarah M., Guan, Li, Villicaña, Sergio, Roberts, Amy L., Zito, Antonino, Bonnycastle, Lori, Erdos, Michael R., Narisu, Narisu, Stringham, Heather M., Welch, Ryan, Yan, Tingfen, Lakka, Timo, Parker, Stephen, Tuomilehto, Jaakko, Seow, Jeffrey, Graham, Carl, Huettner, Isabella, Acors, Sam, Kouphou, Neophytos, Wadge, Samuel, Duncan, Emma L., Steves, Claire J., Doores, Katie J., Malim, Michael H., Collins, Francis S., Pajukanta, Päivi, Boehnke, Michael, Koistinen, Heikki A., Laakso, Markku, Falchi, Mario, Bell, Jordana T., Scott, Laura J., Mohlke, Karen L., Small, Kerrin S.
Published in International Journal of Obesity (01.08.2022)
Published in International Journal of Obesity (01.08.2022)
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Adipose Tissue Gene Expression Associations Reveal Hundreds of Candidate Genes for Cardiometabolic Traits
Raulerson, Chelsea K., Ko, Arthur, Kidd, John C., Currin, Kevin W., Brotman, Sarah M., Cannon, Maren E., Wu, Ying, Spracklen, Cassandra N., Jackson, Anne U., Stringham, Heather M., Welch, Ryan P., Fuchsberger, Christian, Locke, Adam E., Narisu, Narisu, Lusis, Aldons J., Civelek, Mete, Furey, Terrence S., Kuusisto, Johanna, Collins, Francis S., Boehnke, Michael, Scott, Laura J., Lin, Dan-Yu, Love, Michael I., Laakso, Markku, Pajukanta, Päivi, Mohlke, Karen L.
Published in American journal of human genetics (03.10.2019)
Published in American journal of human genetics (03.10.2019)
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Journal Article
Cell-Type Composition Affects Adipose Gene Expression Associations With Cardiometabolic Traits
Brotman, Sarah M, Oravilahti, Anniina, Rosen, Jonathan D, Alvarez, Marcus, Heinonen, Sini, van der Kolk, Birgitta W, Fernandes Silva, Lilian, Perrin, Hannah J, Vadlamudi, Swarooparani, Pylant, Cortney, Deochand, Sonia, Basta, Patricia V, Valone, Jordan M, Narain, Morgan N, Stringham, Heather M, Boehnke, Michael, Kuusisto, Johanna, Love, Michael I, Pietiläinen, Kirsi H, Pajukanta, Päivi, Laakso, Markku, Mohlke, Karen L
Published in Diabetes (New York, N.Y.) (01.11.2023)
Published in Diabetes (New York, N.Y.) (01.11.2023)
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The Evolutionary History of Common Genetic Variants Influencing Human Cortical Surface Area
Tilot, Amanda K, Khramtsova, Ekaterina A, Liang, Dan, Grasby, Katrina L, Jahanshad, Neda, Painter, Jodie, Colodro-Conde, Lucía, Bralten, Janita, Hibar, Derrek P, Lind, Penelope A, Liu, Siyao, Brotman, Sarah M, Thompson, Paul M, Medland, Sarah E, Macciardi, Fabio, Stranger, Barbara E, Davis, Lea K, Fisher, Simon E, Stein, Jason L
Published in Cerebral cortex (New York, N.Y. 1991) (05.03.2021)
Published in Cerebral cortex (New York, N.Y. 1991) (05.03.2021)
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A cross-ancestry genome-wide meta-analysis, fine-mapping, and gene prioritization approach to characterize the genetic architecture of adiponectin
Sarsani, Vishal, Brotman, Sarah M, Xianyong, Yin, Fernandes Silva, Lillian, Laakso, Markku, Spracklen, Cassandra N
Published in HGG advances (11.01.2024)
Published in HGG advances (11.01.2024)
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Identification of type 2 diabetes loci in 433,540 East Asian individuals
Spracklen, Cassandra N., Horikoshi, Momoko, Kim, Young Jin, Lin, Kuang, Moon, Sanghoon, Suzuki, Ken, Tam, Claudia H. T., Tabara, Yasuharu, Kwak, Soo-Heon, Takeuchi, Fumihiko, Long, Jirong, Lim, Victor J. Y., Chai, Jin-Fang, Chen, Chien-Hsiun, Nakatochi, Masahiro, Yao, Jie, Choi, Hyeok Sun, Iyengar, Apoorva K., Perrin, Hannah J., Brotman, Sarah M., van de Bunt, Martijn, Gloyn, Anna L., Below, Jennifer E., Boehnke, Michael, Chambers, John C., Mahajan, Anubha, McCarthy, Mark I., Ng, Maggie C. Y., Petty, Lauren E., Zhang, Weihua, Morris, Andrew P., Adair, Linda S., Akiyama, Masato, Bian, Zheng, Chan, Juliana C. N., Chang, Li-Ching, Chee, Miao-Li, Chen, Yii-Der Ida, Chen, Yuan-Tsong, Chen, Zhengming, Chuang, Lee-Ming, Du, Shufa, Gordon-Larsen, Penny, Gross, Myron, Guo, Xiuqing, Guo, Yu, Han, Sohee, Howard, Annie-Green, Huang, Wei, Hung, Yi-Jen, Hwang, Mi Yeong, Hwu, Chii-Min, Isono, Masato, Jang, Hye-Mi, Jiang, Guozhi, Kamatani, Yoichiro, Katsuya, Tomohiro, Kawaguchi, Takahisa, Lee, Myung-Shik, Lee, Nanette R., Li, Liming, Liu, Jianjun, Luk, Andrea O., Pereira, Mark A., Sabanayagam, Charumathi, Shi, Jinxiu, Shin, Dong Mun, So, Wing Yee, Takahashi, Atsushi, Tomlinson, Brian, van Dam, Rob M., Xiang, Yong-Bing, Yamamoto, Ken, Yamauchi, Toshimasa, Yoon, Kyungheon, Yu, Canqing, Yuan, Jian-Min, Zhang, Liang, Zheng, Wei, Igase, Michiya, Cho, Yoon Shin, Rotter, Jerome I., Wang, Ya-Xing, Sheu, Wayne H. H., Yokota, Mitsuhiro, Wu, Jer-Yuarn, Cheng, Ching-Yu, Shu, Xiao-Ou, Kato, Norihiro, Park, Kyong-Soo, Tai, E-Shyong, Matsuda, Fumihiko, Koh, Woon-Puay, Ma, Ronald C. W., Millwood, Iona Y., Lee, Juyoung, Walters, Robin G., Kim, Bong-Jo, Mohlke, Karen L., Sim, Xueling
Published in Nature (London) (01.06.2020)
Published in Nature (London) (01.06.2020)
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Journal Article
Adipose tissue eQTL meta-analysis reveals the contribution of allelic heterogeneity to gene expression regulation and cardiometabolic traits
Brotman, Sarah M, El-Sayed Moustafa, Julia S, Guan, Li, Broadaway, K Alaine, Wang, Dongmeng, Jackson, Anne U, Welch, Ryan, Currin, Kevin W, Tomlinson, Max, Vadlamudi, Swarooparani, Stringham, Heather M, Roberts, Amy L, Lakka, Timo A, Oravilahti, Anniina, Silva, Lilian Fernandes, Narisu, Narisu, Erdos, Michael R, Yan, Tingfen, Bonnycastle, Lori L, Raulerson, Chelsea K, Raza, Yasrab, Yan, Xinyu, Parker, Stephen C J, Kuusisto, Johanna, Pajukanta, Päivi, Tuomilehto, Jaakko, Collins, Francis S, Boehnke, Michael, Love, Michael I, Koistinen, Heikki A, Laakso, Markku, Mohlke, Karen L, Small, Kerrin S, Scott, Laura J
Published in bioRxiv (27.10.2023)
Published in bioRxiv (27.10.2023)
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Journal Article
ACE2 expression in adipose tissue is associated with COVID-19 cardio-metabolic risk factors and cell type composition
El-Sayed Moustafa, Julia S, Jackson, Anne U, Brotman, Sarah M, Guan, Li, Villicaña, Sergio, Roberts, Amy L, Zito, Antonino, Bonnycastle, Lori, Erdos, Michael R, Narisu, Narisu, Stringham, Heather M, Welch, Ryan, Yan, Tingfen, Lakka, Timo, Parker, Stephen, Tuomilehto, Jaakko, Collins, Francis S, Pajukanta, Päivi, Boehnke, Michael, Koistinen, Heikki A, Laakso, Markku, Falchi, Mario, Bell, Jordana T, Scott, Laura J, Mohlke, Karen L, Small, Kerrin S
Published in medRxiv : the preprint server for health sciences (14.08.2020)
Published in medRxiv : the preprint server for health sciences (14.08.2020)
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Journal Article
Identification of type 2 diabetes loci in 433,540 East Asian individuals
Spracklen, Cassandra N, Horikoshi, Momoko, Young Jin Kim, Lin, Kuang, Moon, Sanghoon, Suzuki, Ken, Tam, Claudia, Tabara, Yasuharu, Soo-Heon Kwak, Long, Jirong, Jin-Fang, Chai, Chen, Chien-Hsiun, Nakatochi, Masahiro, Yao, Jie, Hyeok Sun Choi, Perrin, Hannah J, Brotman, Sarah M, Van De Bunt, Martijn, Gloyn, Anna L, Boehnke, Michael, Bowden, Donald W, Chambers, John C, Mahajan, Anubha, Mccarthy, Mark I, Ng, Maggie Cy, Petty, Lauren E, Zhang, Weihua, Morris, Andrew P, Adair, Linda S, Bian, Zheng, Li-Ching, Chang, Miao-Li, Chee, Chen, Yii-Der Ida, Yuan-Tsong, Chen, Chen, Zhengming, Lee-Ming, Chuang, Du, Shufa, Gordon-Larsen, Penny, Gross, Myron, Guo, Xiuqing, Guo, Yu, Han, Sohee, Annie-Green, Howard, Huang, Wei, Yi-Jen, Hung, Hwang, Mi Yeong, Chii-Min Hwu, Ichihara, Sahoko, Isono, Masato, Hye-Mi Jang, Jiang, Guozhi, Jonas, Jost B, Kamatani, Yoichiro, Katsuya, Tomohiro, Kawaguchi, Takahisa, Khor, Chiea-Chuen, Lee, Myung-Shik, Lee, Nannette R, Li, Liming, Liu, Jianjun, Luk, Andrea O, Okada, Yukinori, Pereira, Mark A, Charumathi Sabanayagam, Shi, Jinxiu, So, Wing Yee, Takahashi, Atsushi, Van Dam, Rob M, Yong-Bing, Xiang, Yamamoto, Ken, Yamauchi, Toshimasa, Yoon, Kyungheon, Yu, Canqing, Jian-Min, Yuan, Zhang, Liang, Zheng, Wei, Igase, Michiya, Yoon Shin Cho, Rotter, Jerome I, Ya-Xing, Wang, Sheu, Wayne Hh, Yokota, Mitsuhiro, Wu, Jer-Yuarn, Ching-Yu, Cheng, Tien-Yin, Wong, Xiao-Ou, Shu, Kato, Norihiro, Park, Kyong-Soo, E-Shyong, Tai, Matsuda, Fumihiko, Koh, Woon-Puay, Cw, Ronald, Maeda, Shiro, Millwood, Iona Y, Lee, Juyoung, Kadowaki, Takashi, Walters, Robin G, Bong-Jo, Kim, Mohlke, Karen L, Sim, Xueling
Published in bioRxiv (28.06.2019)
Published in bioRxiv (28.06.2019)
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The Evolutionary History of Common Genetic Variants Influencing Human Cortical Surface Area
Tilot, Amanda L, Khramtsova, Ekaterina A, Grasby, Katrina, Jahanshad, Neda, Painter, Jodie, Lucia Colodro Conde, Bralten, Janita, Hibar, Derrek P, Lind, Penelope, Liu, Siyao, Brotman, Sarah M, Thompson, Paul M, Medland, Sarah E, Macciardi, Fabio, Stranger, Barbara E, Davis, Lea K, Fisher, Simon E, Stein, Jason
Published in bioRxiv (16.07.2019)
Published in bioRxiv (16.07.2019)
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