IVA337, a pan-ppar agonist, reduces non-alcoholic steatohepatitis feature and inhibits the inflammasome in murin models of non-alcoholic steatohepatitis
Wettstein, G, Poekes, L, Oakley, F, Faye, P, Luccarini, J.-M, Broqua, P, Junien, J.-L, Mann, D, Leclercq, I, Konstantinova, I
Published in Journal of hepatology (2017)
Published in Journal of hepatology (2017)
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AB0206 Pan-Ppar Agonist IVA337 is Effective in Prevention and Treatment of Experimental Skin Fibrosis
Ruzehaji, N., Frantz, C., Ponsoye, M., Avouac, J., Konstantinova, I., Fromond, C., Broqua, P., Junien, J.L., Allanore, Y.
Published in Annals of the rheumatic diseases (01.06.2015)
Published in Annals of the rheumatic diseases (01.06.2015)
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Journal Article
The New Generation Pan-Ppar Agonist Iva337 Protects the Liver from Metabolic Disorders and Fibrosis
Wettstein, G, Estivalet, C, Tessier, J, Boustugue, P.T, Jantzen, I, Defrene, E, Kupkowski, F, Faye, P, Adarbes, V, Germain, J.-M, Vasseur, E, Robert, C, Fromond, C, Broqua, P, Junien, J.-L, Luccarini, J.-M, Konstantinova, I
Published in Journal of hepatology (2016)
Published in Journal of hepatology (2016)
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594 Identification of novel EZH2 inhibitor scaffolds
Espanel, X, Chene, L, Soude, A, Estevez, S, Adarbes, V, Loillier, B, Boubia, B, Masson, P, Montalbetti, C, Broqua, P, Fromond, C
Published in European journal of cancer (1990) (01.11.2014)
Published in European journal of cancer (1990) (01.11.2014)
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557 A rational approach for discovery of inhibitors of YAP-TEAD interaction
Chene, L, Soude, A, Valaire, C, Delaporte, S, Jacquet, S, Cambet, Y, Braccini, I, Barth, M, Montalbetti, C, Broqua, P, Fromond, C
Published in European journal of cancer (1990) (01.11.2014)
Published in European journal of cancer (1990) (01.11.2014)
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Chronic administration of neuropeptide Y into the lateral ventricle of C57BL/6J male mice produces an obesity syndrome including hyperphagia, hyperleptinemia, insulin resistance, and hypogonadism
Raposinho, P.D., Pierroz, D.D., Broqua, P., White, R.B., Pedrazzini, T., Aubert, M.L.
Published in Molecular and cellular endocrinology (20.12.2001)
Published in Molecular and cellular endocrinology (20.12.2001)
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GnRH Antagonists: A New Generation of Long Acting Analogues Incorporating p-Ureido-phenylalanines at Positions 5 and 6
Jiang, Guangcheng, Stalewski, Jacek, Galyean, Robert, Dykert, John, Schteingart, Claudio, Broqua, Pierre, Aebi, Audrey, Aubert, Michel L, Semple, Graeme, Robson, Peter, Akinsanya, Karen, Haigh, Robert, Riviere, Pierre, Trojnar, Jerzy, Junien, Jean Louis, Rivier, Jean E
Published in Journal of medicinal chemistry (01.02.2001)
Published in Journal of medicinal chemistry (01.02.2001)
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OP0081 PAN-PPAR agonist IVA337 is effective in the prevention of experimental lung fibrosis and pulmonary hypertension
Avouac, J, Konstantinova, I, Guignabert, C, Sadoine, J, Thomas, G, Pezet, S, Cauvet, A, Tu, L, Luccarini, JM, Junien, JL, Broqua, P, Allanore, Y
Published in Annals of the rheumatic diseases (01.06.2017)
Published in Annals of the rheumatic diseases (01.06.2017)
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Journal Article
THU-391 - IVA337, a pan-ppar agonist, reduces non-alcoholic steatohepatitis feature and inhibits the inflammasome in murin models of non-alcoholic steatohepatitis
Wettstein, G., Poekes, L., Oakley, F., Faye, P., Luccarini, J.-M., Broqua, P., Junien, J.-L., Mann, D., Leclercq, I., Konstantinova, I.
Published in Journal of hepatology (2017)
Published in Journal of hepatology (2017)
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Journal Article
PS068 - The New Generation Pan-Ppar Agonist Iva337 Protects the Liver from Metabolic Disorders and Fibrosis
Wettstein, G., Estivalet, C., Tessier, J., Boustugue, P.T., Jantzen, I., Defrene, E., Kupkowski, F., Faye, P., Adarbes, V., Germain, J.-M., Vasseur, E., Robert, C., Fromond, C., Broqua, P., Junien, J.-L., Luccarini, J.-M., Konstantinova, I.
Published in Journal of hepatology (2016)
Published in Journal of hepatology (2016)
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Chronic Inhibition of Circulating Dipeptidyl Peptidase IV by FE 999011 Delays the Occurrence of Diabetes in Male Zucker Diabetic Fatty Rats
SUDRE, Béatrice, BROQUA, Pierre, WHITE, Richard B, ASHWORTH, Doreen, EVANS, D. Michael, HAIGH, Robert, JUNIEN, Jean-Louis, AUBERT, Michel L
Published in Diabetes (New York, N.Y.) (01.05.2002)
Published in Diabetes (New York, N.Y.) (01.05.2002)
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Pharmacological Profile of a New, Potent, and Long-Acting Gonadotropin-Releasing Hormone Antagonist: Degarelix
Broqua, Pierre, Riviere, Pierre J-M, Conn, P Michael, Rivier, Jean E, Aubert, Michel L, Junien, Jean-Louis
Published in The Journal of pharmacology and experimental therapeutics (01.04.2002)
Published in The Journal of pharmacology and experimental therapeutics (01.04.2002)
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Evidence that the inhibition of luteinizing hormone secretion exerted by central administration of neuropeptide Y (NPY) in the rat is predominantly mediated by the NPY-Y5 receptor subtype
Raposinho, P D, Broqua, P, Pierroz, D D, Hayward, A, Dumont, Y, Quirion, R, Junien, J L, Aubert, M L
Published in Endocrinology (Philadelphia) (01.09.1999)
Published in Endocrinology (Philadelphia) (01.09.1999)
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Chronic blockade of the melanocortin 4 receptor subtype leads to obesity independently of neuropeptide Y action, with no adverse effects on the gonadotropic and somatotropic axes
Raposinho, P D, Castillo, E, d'Alleves, V, Broqua, P, Pralong, F P, Aubert, M L
Published in Endocrinology (Philadelphia) (01.12.2000)
Published in Endocrinology (Philadelphia) (01.12.2000)
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L’agoniste pan-PPAR IVA337 est efficace pour la prévention de la fibrose pulmonaire et de l’hypertension pulmonaire expérimentales
Avouac, J., Konstantinova, I., Guignabert, C., Jeremy, S., Guilbert, T., Pezet, S., Cauvet, A., Luccarini, J.M., Junien, J.L., Broqua, P., Allanore, Y.
Published in Revue du rhumatisme (Ed. française : 1993) (01.11.2016)
Published in Revue du rhumatisme (Ed. française : 1993) (01.11.2016)
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