Inhibition of phosphatidylinositol-3-kinase and mitogen-activated protein kinase kinase 1/2 prevents melanoma development and promotes melanoma regression in the transgenic TPRas mouse model
Bedogni, Barbara, Welford, Scott M, Kwan, Andrea C, Ranger-Moore, James, Saboda, Kathylynn, Powell, Marianne Broome
Published in Molecular cancer therapeutics (01.12.2006)
Published in Molecular cancer therapeutics (01.12.2006)
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Notch1 is an effector of Akt and hypoxia in melanoma development
Bedogni, Barbara, Warneke, James A, Nickoloff, Brian J, Giaccia, Amato J, Powell, Marianne Broome
Published in The Journal of clinical investigation (01.11.2008)
Published in The Journal of clinical investigation (01.11.2008)
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Journal Article
Neonatal Ultraviolet Radiation Exposure Is Critical for Malignant Melanoma Induction in Pigmented Tpras Transgenic Mice
Hacker, Elke, Irwin, Nicole, Konrad Muller, H., Powell, Marianne Broome, Kay, Graham, Hayward, Nicholas, Walker, Graeme
Published in Journal of investigative dermatology (01.11.2005)
Published in Journal of investigative dermatology (01.11.2005)
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Journal Article
Hypoxic induction of AKAP12 variant 2 shifts PKA-mediated protein phosphorylation to enhance migration and metastasis of melanoma cells
Finger, Elizabeth C., Castellini, Laura, Rankin, Erinn B., Vilalta, Marta, Krieg, Adam J., Jiang, Dadi, Banh, Alice, Zundel, Wayne, Powell, Marianne Broome, Giaccia, Amato J.
Published in Proceedings of the National Academy of Sciences - PNAS (07.04.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (07.04.2015)
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HIF1α delays premature senescence through the activation of MIF
Welford, Scott M., Bedogni, Barbara, Gradin, Katarina, Poellinger, Lorenz, Broome Powell, Marianne, Giaccia, Amato J.
Published in Genes & development (15.12.2006)
Published in Genes & development (15.12.2006)
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Journal Article
VHL loss in renal cell carcinoma leads to up-regulation of CUB domain-containing protein 1 to stimulate PKCδ-driven migration
Razorenova, Olga V, Finger, Elizabeth C, Colavitti, Renata, Chernikova, Sophia B, Boiko, Alexander D, Chan, Charles K.F, Krieg, Adam, Bedogni, Barbara, LaGory, Edward, Weissman, Irving L, Broome-Powell, Marianne, Giaccia, Amato J
Published in Proceedings of the National Academy of Sciences - PNAS (01.02.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (01.02.2011)
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Journal Article
Induction of melanoma in TPras transgenic mice
Powell, Marianne Broome, Gause, Paul R., Hyman, Paul, Gregus, Jacalyn, Lluria-Prevatt, Maria, Nagle, Ray, Bowden, G. Tim
Published in Carcinogenesis (New York) (01.09.1999)
Published in Carcinogenesis (New York) (01.09.1999)
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Targeting integrins and PI3K/Akt-mediated signal transduction pathways enhances radiation-induced anti-angiogenesis
Ning, Shoucheng, Chen, Zhijian, Dirks, Amie, Husbeck, Bryan, Hsu, Mark, Bedogni, Barbara, O'Neill, Melony, Powell, Marianne Broome, Knox, Susan J
Published in Radiation research (01.07.2007)
Published in Radiation research (01.07.2007)
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Journal Article
Unique transforming properties of Notch1 in human melanocytes
Bedogni, Barbara, Powell, Marianne Broome
Published in Pigment cell and melanoma research (01.12.2009)
Published in Pigment cell and melanoma research (01.12.2009)
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Journal Article
Topical treatment with inhibitors of the phosphatidylinositol 3'-kinase/Akt and Raf/mitogen-activated protein kinase kinase/extracellular signal-regulated kinase pathways reduces melanoma development in severe combined immunodeficient mice
BEDOGNI, Barbara, O'NEILL, Melony S, WELFORD, Scott M, BOULEY, Donna M, GIACCIA, Amato J, DENKO, Nicholas C, POWELL, Marianne Broome
Published in Cancer research (Chicago, Ill.) (01.04.2004)
Published in Cancer research (Chicago, Ill.) (01.04.2004)
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Journal Article
Abstract LB-357: HIF-dependent over-expression of CUB domain-containing protein 1 stimulates migration in clear cell renal cell carcinoma
Razorenova, Olga V., Finger, Elizabeth C., Colavitti, Renata, Chernikova, Sophia B., Boiko, Alexander D., Chan, Charles KF, Krieg, Adam, Bedogni, Barbara, LaGory, Edward, Weissman, Irving L., Broome-Powell, Marianne, Giaccia, Amato J.
Published in Cancer research (Chicago, Ill.) (15.04.2011)
Published in Cancer research (Chicago, Ill.) (15.04.2011)
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Journal Article
VHL loss in renal cell carcinoma leads to up-regulation of CUB domain-containing protein 1 to stimulate PKC{delta}-driven migration
Razorenova, Olga V, Finger, Elizabeth C, Colavitti, Renata, Chernikova, Sophia B, Boiko, Alexander D, Chan, Charles K F, Krieg, Adam, Bedogni, Barbara, LaGory, Edward, Weissman, Irving L, Broome-Powell, Marianne, Giaccia, Amato J
Published in Proceedings of the National Academy of Sciences - PNAS (01.02.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (01.02.2011)
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Journal Article
VHL loss in renal cell carcinoma leads to up-regulation of CUB domain-containing protein 1 to stimulate PKCδ-driven migration
Razorenova, Olga V, Finger, Elizabeth C, Colavitti, Renata, Chernikova, Sophia B, Boiko, Alexander D, Chan, Charles K.F, Krieg, Adam, Bedogni, Barbara, LaGory, Edward, Weissman, Irving L, Broome-Powell, Marianne, Giaccia, Amato J
Published in Proceedings of the National Academy of Sciences - PNAS (2011)
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Published in Proceedings of the National Academy of Sciences - PNAS (2011)
Journal Article
Spontaneous and UV radiation-induced multiple metastatic melanomas in Cdk4R24C/R24C/TPras mice
HACKER, Elke, MULLER, H. Konrad, WALKER, Graeme, IRWIN, Nicole, GABRIELLI, Brian, LINCOLN, Douglas, PAVEY, Sandra, POWELL, Marianne Broome, MALUMBRES, Marcos, BARBACID, Mariano, HAYWARD, Nicholas
Published in Cancer research (Chicago, Ill.) (15.03.2006)
Published in Cancer research (Chicago, Ill.) (15.03.2006)
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