Bortezomib sensitizes human renal cell carcinomas to TRAIL apoptosis through increased activation of caspase-8 in the death-inducing signaling complex
Brooks, Alan D, Jacobsen, Kristen M, Li, Wenqing, Shanker, Anil, Sayers, Thomas J
Published in Molecular cancer research (01.05.2010)
Published in Molecular cancer research (01.05.2010)
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Journal Article
The proteasome inhibitor PS-341 sensitizes neoplastic cells to TRAIL-mediated apoptosis by reducing levels of c-FLIP
Sayers, Thomas J., Brooks, Alan D., Koh, Crystal Y., Ma, Weihong, Seki, Naoko, Raziuddin, Arati, Blazar, Bruce R., Zhang, Xia, Elliott, Peter J., Murphy, William J.
Published in Blood (01.07.2003)
Published in Blood (01.07.2003)
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Journal Article
cell-based high-throughput screen to identify synergistic TRAIL sensitizers
Booth, Nancy Lynn, Sayers, Thomas J, Brooks, Alan D, Thomas, Cheryl L, Jacobsen, Kristen, Goncharova, Ekaterina I, McMahon, James B, Henrich, Curtis J
Published in Cancer Immunology, Immunotherapy (01.08.2009)
Published in Cancer Immunology, Immunotherapy (01.08.2009)
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Journal Article
Tumor-Specific CTL Kill Murine Renal Cancer Cells Using Both Perforin and Fas Ligand-Mediated Lysis In Vitro, But Cause Tumor Regression In Vivo in the Absence of Perforin
Seki, Naoko, Brooks, Alan D, Carter, Clive R. D, Back, Timothy C, Parsoneault, Erin M, Smyth, Mark J, Wiltrout, Robert H, Sayers, Thomas J
Published in The Journal of immunology (1950) (01.04.2002)
Published in The Journal of immunology (1950) (01.04.2002)
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Journal Article
The Proteasome Inhibitor Bortezomib (Velcade) Sensitizes Some Human Tumor Cells to Apo2L/TRAIL-Mediated Apoptosis
BROOKS, ALAN D., RAMIREZ, TERESA, TOH, UHI, ONKSEN, JENNIFER, ELLIOTT, PETER J., MURPHY, WILLIAM J., SAYERS, THOMAS J.
Published in Annals of the New York Academy of Sciences (01.11.2005)
Published in Annals of the New York Academy of Sciences (01.11.2005)
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Journal Article
Withanolides from Aeroponically Grown Physalis peruviana and Their Selective Cytotoxicity to Prostate Cancer and Renal Carcinoma Cells
Xu, Ya-Ming, Wijeratne, E. M. Kithsiri, Babyak, Ashley L, Marks, Hanna R, Brooks, Alan D, Tewary, Poonam, Xuan, Li-Jiang, Wang, Wen-Qiong, Sayers, Thomas J, Gunatilaka, A. A. Leslie
Published in Journal of natural products (Washington, D.C.) (28.07.2017)
Published in Journal of natural products (Washington, D.C.) (28.07.2017)
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Journal Article
Cytotoxic and other withanolides from aeroponically grown Physalis philadelphica
Xu, Ya-Ming, Wijeratne, E.M. Kithsiri, Brooks, Alan D., Tewary, Poonam, Xuan, Li-Jiang, Wang, Wen-Qiong, Sayers, Thomas J., Gunatilaka, A.A. Leslie
Published in Phytochemistry (Oxford) (01.08.2018)
Published in Phytochemistry (Oxford) (01.08.2018)
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Journal Article
Ring A/B-Modified 17β-Hydroxywithanolide Analogues as Antiproliferative Agents for Prostate Cancer and Potentiators of Immunotherapy for Renal Carcinoma and Melanoma
Kithsiri Wijeratne, E. M, Xu, Ya-Ming, Liu, Manping X, Inacio, Marielle C, Brooks, Alan D, Tewary, Poonam, Sayers, Thomas J, Gunatilaka, A. A. Leslie
Published in Journal of natural products (Washington, D.C.) (24.12.2021)
Published in Journal of natural products (Washington, D.C.) (24.12.2021)
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Journal Article
Small-Molecule Natural Product Physachenolide C Potentiates Immunotherapy Efficacy by Targeting BET Proteins
Tewary, Poonam, Brooks, Alan D, Xu, Ya-Ming, Wijeratne, E M Kithsiri, Babyak, Ashley L, Back, Timothy C, Chari, Raj, Evans, Christine N, Henrich, Curtis J, Meyer, Thomas J, Edmondson, Elijah F, de Aquino, Maria T Prudente, Kanagasabai, Thanigaivelan, Shanker, Anil, Gunatilaka, A A Leslie, Sayers, Thomas J
Published in Cancer research (Chicago, Ill.) (15.06.2021)
Published in Cancer research (Chicago, Ill.) (15.06.2021)
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Journal Article
The Restricted Expression of Granzyme M in Human Lymphocytes
Sayers, Thomas J, Brooks, Alan D, Ward, Jerrold M, Hoshino, Tomoaki, Bere, William E, Wiegand, Gordon W, Kelley, Janice M, Smyth, Mark J
Published in The Journal of immunology (1950) (15.01.2001)
Published in The Journal of immunology (1950) (15.01.2001)
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Journal Article
17β-Hydroxywithanolides as Sensitizers of Renal Carcinoma Cells to Tumor Necrosis Factor‑α Related Apoptosis Inducing Ligand (TRAIL) Mediated Apoptosis: Structure–Activity Relationships
Xu, Ya-Ming, Brooks, Alan D, Wijeratne, E. M. Kithsiri, Henrich, Curtis J, Tewary, Poonam, Sayers, Thomas J, Gunatilaka, A. A. Leslie
Published in Journal of medicinal chemistry (13.04.2017)
Published in Journal of medicinal chemistry (13.04.2017)
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Journal Article
Bortezomib Improves Adoptive T-cell Therapy by Sensitizing Cancer Cells to FasL Cytotoxicity
Shanker, Anil, Pellom, Jr, Samuel T, Dudimah, Duafalia F, Thounaojam, Menaka C, de Kluyver, Rachel L, Brooks, Alan D, Yagita, Hideo, McVicar, Daniel W, Murphy, William J, Longo, Dan L, Sayers, Thomas J
Published in Cancer research (Chicago, Ill.) (15.12.2015)
Published in Cancer research (Chicago, Ill.) (15.12.2015)
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Immunologic and Therapeutic Synergy of IL-27 and IL-2: Enhancement of T Cell Sensitization, Tumor-Specific CTL Reactivity and Complete Regression of Disseminated Neuroblastoma Metastases in the Liver and Bone Marrow
Salcedo, Rosalba, Hixon, Julie A, Stauffer, Jimmy K, Jalah, Rashmi, Brooks, Alan D, Khan, Tahira, Dai, Ren-Ming, Scheetz, Loretta, Lincoln, Erin, Back, Timothy C, Powell, Douglas, Hurwitz, Arthur A, Sayers, Thomas J, Kastelein, Robert, Pavlakis, George N, Felber, Barbara K, Trinchieri, Giorgio, Wigginton, Jon M
Published in The Journal of immunology (1950) (01.04.2009)
Published in The Journal of immunology (1950) (01.04.2009)
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Effects of cucurbitacins on cell morphology are associated with sensitization of renal carcinoma cells to TRAIL-induced apoptosis
Henrich, Curtis J., Thomas, Cheryl L., Brooks, Alan D., Booth, Nancy Lynn, Lowery, Evan M., Pompei, Richard J., McMahon, James B., Sayers, Thomas J.
Published in Apoptosis (London) (2012)
Published in Apoptosis (London) (2012)
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Tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis is an important endogenous mechanism for resistance to liver metastases in murine renal cancer
SEKI, Naoko, HAYAKAWA, Yoshihiro, BROOKS, Alan D, WINE, John, WILTROUT, Robert H, YAGITA, Hideo, TANNER, Jane E, SMYTH, Mark J, SAYERS, Thomas J
Published in Cancer research (Chicago, Ill.) (2003)
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Published in Cancer research (Chicago, Ill.) (2003)
Journal Article
NK Cells Use NKG2D to Recognize a Mouse Renal Cancer (Renca), yet Require Intercellular Adhesion Molecule-1 Expression on the Tumor Cells for Optimal Perforin-Dependent Effector Function
Abdool, Karen, Cretney, Erika, Brooks, Alan D, Kelly, Janice M, Swann, Jeremy, Shanker, Anil, Bere, Earl W., Jr, Yokoyama, Wayne M, Ortaldo, John R, Smyth, Mark J, Sayers, Thomas J
Published in Journal of Immunology (15.08.2006)
Published in Journal of Immunology (15.08.2006)
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