Astegolimab, an anti-ST2, in chronic obstructive pulmonary disease (COPD-ST2OP): a phase 2a, placebo-controlled trial
Yousuf, Ahmed J, Mohammed, Seid, Carr, Liesl, Yavari Ramsheh, Mohammadali, Micieli, Claudia, Mistry, Vijay, Haldar, Kairobi, Wright, Adam, Novotny, Petr, Parker, Sarah, Glover, Sarah, Finch, Joanne, Quann, Niamh, Brookes, Cassandra L, Hobson, Rachel, Ibrahim, Wadah, Russell, Richard J, John, Catherine, Grimbaldeston, Michele A, Choy, David F, Cheung, Dorothy, Steiner, Michael, Greening, Neil J, Brightling, Christopher E
Published in The lancet respiratory medicine (01.05.2022)
Published in The lancet respiratory medicine (01.05.2022)
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Mutational analysis of PI3K/AKT signaling pathway in tamoxifen exemestane adjuvant multinational pathology study
Sabine, Vicky S, Crozier, Cheryl, Brookes, Cassandra L, Drake, Camilla, Piper, Tammy, van de Velde, Cornelis J H, Hasenburg, Annette, Kieback, Dirk G, Markopoulos, Christos, Dirix, Luc, Seynaeve, Caroline, Rea, Daniel W, Bartlett, John M S
Published in Journal of clinical oncology (20.09.2014)
Published in Journal of clinical oncology (20.09.2014)
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Estrogen Receptor and Progesterone Receptor As Predictive Biomarkers of Response to Endocrine Therapy: A Prospectively Powered Pathology Study in the Tamoxifen and Exemestane Adjuvant Multinational Trial
BARTLETT, John M. S, BROOKES, Cassandra L, KIEBACK, Dirk G, PUTTER, Hein, MARKOPOULOS, Christos, MEERSHOEK-KLEIN KRANENBARG, Elma, MALLON, Elizabeth A, DIRIX, Luc, SEYNAEVE, Caroline, REA, Daniel, ROBSON, Tammy, VAN DE VELDE, Cornelis J. H, BILLINGHAM, Lucinda J, CAMPBELL, Fiona M, GRANT, Margaret, HASENBURG, Annette, HILLE, Elysée T. M, KAY, Charlene
Published in Journal of clinical oncology (20.04.2011)
Published in Journal of clinical oncology (20.04.2011)
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Journal Article
Rationale and design of the early valve replacement in severe asymptomatic aortic stenosis trial
Richardson, Carla, Gilbert, Tom, Aslam, Saadia, Brookes, Cassandra L., Singh, Anvesha, Newby, David E., Dweck, Marc R., Stewart, Ralph A. H., Myles, Paul S., Briffa, Tom, Selvanayagam, Joseph, Chow, Clara K., Murphy, Gavin J., Akowuah, Enoch F., Lord, Joanne, Barber, Shaun, Paola, Ana Suazo Di, McCann, Gerry P., Hillis, Graham S.
Published in The American heart journal (01.09.2024)
Published in The American heart journal (01.09.2024)
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Journal Article
Prognostic factor analysis of the survival of elderly patients with AML in the MRC AML11 and LRF AML14 trials
Wheatley, Keith, Brookes, Cassandra L., Howman, Andrew J., Goldstone, Anthony H., Milligan, Donald W., Prentice, Archibald G., Moorman, Anthony V., Burnett, Alan K.
Published in British journal of haematology (01.06.2009)
Published in British journal of haematology (01.06.2009)
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Pathway-based subnetworks enable cross-disease biomarker discovery
Haider, Syed, Yao, Cindy Q., Sabine, Vicky S., Grzadkowski, Michal, Stimper, Vincent, Starmans, Maud H. W., Wang, Jianxin, Nguyen, Francis, Moon, Nathalie C., Lin, Xihui, Drake, Camilla, Crozier, Cheryl A., Brookes, Cassandra L., van de Velde, Cornelis J. H., Hasenburg, Annette, Kieback, Dirk G., Markopoulos, Christos J., Dirix, Luc Y., Seynaeve, Caroline, Rea, Daniel W., Kasprzyk, Arek, Lambin, Philippe, Lio’, Pietro, Bartlett, John M. S., Boutros, Paul C.
Published in Nature communications (12.11.2018)
Published in Nature communications (12.11.2018)
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Journal Article
The effectiveness of the Structured Health Intervention For Truckers (SHIFT): a cluster randomised controlled trial (RCT)
Clemes, Stacy A, Varela-Mato, Veronica, Bodicoat, Danielle H, Brookes, Cassandra L, Chen, Yu-Ling, Edwardson, Charlotte L, Gray, Laura J, Guest, Amber J, Johnson, Vicki, Munir, Fehmidah, Paine, Nicola J, Richardson, Gerry, Ruettger, Katharina, Sayyah, Mohsen, Sherry, Aron, Di Paola, Ana Suazo, Troughton, Jacqui, Yates, Thomas, King, James A
Published in BMC medicine (24.05.2022)
Published in BMC medicine (24.05.2022)
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A gut microbiota rheostat forecasts responsiveness to PD-L1 and VEGF blockade in mesothelioma
Zhang, Min, Bzura, Aleksandra, Baitei, Essa Y., Zhou, Zisen, Spicer, Jake B., Poile, Charlotte, Rogel, Jan, Branson, Amy, King, Amy, Barber, Shaun, Kamata, Tamihiro, Dzialo, Joanna, Harber, James, Greystoke, Alastair, Nusrat, Nada, Faulkner, Daniel, Sun, Qianqian, Nolan, Luke, Hahne, Jens C., Scotland, Molly, Walter, Harriet, Darlison, Liz, Morgan, Bruno, Bajaj, Amrita, Brookes, Cassandra, Hollox, Edward J., Lubawska, Dominika, Jama, Maymun, Griffiths, Gareth, Nakas, Apostolos, Kutywayo, Kudzayi, Luo, Jin-Li, Klampatsa, Astero, Cooper, Andrea, Halder, Koirobi, Wells-Jordan, Peter, Zhou, Huiyu, Dudbridge, Frank, Thomas, Anne, Richards, Catherine Jane, Pritchard, Catrin, Yang, Hongji, Barer, Michael, Fennell, Dean A.
Published in Nature communications (21.08.2024)
Published in Nature communications (21.08.2024)
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Synchronous versus sequential chemo-radiotherapy in patients with early stage breast cancer (SECRAB): A randomised, phase III, trial
Fernando, Indrajit N., Bowden, Sarah J., Herring, Kathryn, Brookes, Cassandra L., Ahmed, Ikhlaaq, Marshall, Andrea, Grieve, Robert, Churn, Mark, Spooner, David, Latief, Talaat N., Agrawal, Rajiv K., Brunt, Adrian M., Stevens, Andrea, Goodman, Andrew, Canney, Peter, Bishop, Jill, Ritchie, Diana, Dunn, Janet, Poole, Christopher J., Rea, Daniel W.
Published in Radiotherapy and oncology (01.01.2020)
Published in Radiotherapy and oncology (01.01.2020)
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The NightLife study - the clinical and cost-effectiveness of thrice-weekly, extended, in-centre nocturnal haemodialysis versus daytime haemodialysis using a mixed methods approach: study protocol for a randomised controlled trial
Hull, Katherine L, Bramham, Kate, Brookes, Cassandra L, Cluley, Victoria, Conefrey, Carmel, Cooper, Nicola J, Eborall, Helen, Fotheringham, James, Graham-Brown, Matthew P M, Gray, Laura J, Mark, Patrick B, Mitra, Sandip, Murphy, Gavin J, Quann, Niamh, Rooshenas, Leila, Warren, Madeleine, Burton, James O
Published in Current controlled trials in cardiovascular medicine (12.08.2023)
Published in Current controlled trials in cardiovascular medicine (12.08.2023)
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Journal Article
ASSERT (Acute Sacral inSufficiEncy fractuRe augmenTation): randomised controlled, feasibility trial in older people
Ong, Terence, Suazo Di Paola, Ana, Brookes, Cassandra, Drummond, Avril, Hendrick, Paul, Leighton, Paul, Jones, Matthew, Salem, Khalid, Quraishi, Nasir, Sahota, Opinder
Published in BMJ open (03.05.2022)
Published in BMJ open (03.05.2022)
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HER2 status predicts for upfront AI benefit: A TRANS-AIOG meta-analysis of 12,129 patients from ATAC, BIG 1-98 and TEAM with centrally determined HER2
Bartlett, John M.S, Ahmed, Ikhlaaq, Regan, Meredith M, Sestak, Ivana, Mallon, Elizabeth A, Dell'Orto, Patrizia, Thürlimann, Beat, Seynaeve, Caroline, Putter, Hein, Van de Velde, Cornelis J.H, Brookes, Cassandra L, Forbes, John F, Viale, Giuseppe, Cuzick, Jack, Dowsett, Mitchell, Rea, Daniel W
Published in European journal of cancer (1990) (01.07.2017)
Published in European journal of cancer (1990) (01.07.2017)
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ASSERT (Acute Sacral inSufficiEncy fractuRe augmenTation) randomised controlled, feasibility in older people trial: a study protocol
van Berkel, Dawn, Ong, Terence, Drummond, Avril, Hendrick, Paul, Leighton, Paul, Jones, Matthew, Salem, Khalid, Quraishi, Nasir, Brookes, Cassandra, Suazo Di Paola, Ana, Edwards, Sarah, Sahota, Opinder
Published in BMJ open (01.07.2019)
Published in BMJ open (01.07.2019)
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Connectivity guided theta burst transcranial magnetic stimulation versus repetitive transcranial magnetic stimulation for treatment-resistant moderate to severe depression: study protocol for a randomised double-blind controlled trial (BRIGhTMIND)
Morriss, Richard, Webster, Lucy, Abdelghani, Mohamed, Auer, Dorothee P, Barber, Shaun, Bates, Peter, Blamire, Andrew, Briley, Paul M, Brookes, Cassandra, Iwabuchi, Sarina, James, Marilyn, Kaylor-Hughes, Catherine, Lankappa, Sudheer, Liddle, Peter, McAllister-Williams, Hamish, O'Neill-Kerr, Alex, Pszczolkowski Parraguez, Stefan, Suazo Di Paola, Ana, Thomson, Louise, Walters, Yvette
Published in BMJ open (07.07.2020)
Published in BMJ open (07.07.2020)
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Factors predicting long-term survival after T-cell depleted reduced intensity allogeneic stem cell transplantation for acute myeloid leukemia
CRADDOCK, Charles, NAGRA, Sandeep, KOTTARIDIS, Panos, SNOWDEN, John, MILLIGAN, Donald, COOK, Gordon, THOLOULI, Eleni, LITTLEWOOD, Tim, PEGGS, Karl, VYAS, Paresh, CLARK, Fiona, COOK, Mark, PENIKET, Andrew, MACKINNON, Stephen, RUSSELL, Nigel, BROOKES, Cassandra, BUCKLEY, Laura, NIKOLOUSIS, Emmanouil, DUNCAN, Nick, TAURO, Sudhir, YIN, John, LIAKOPOULOU, Effie
Published in Haematologica (Roma) (01.06.2010)
Published in Haematologica (Roma) (01.06.2010)
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Journal Article
Molecular stratification of early breast cancer identifies drug targets to drive stratified medicine
Bayani, Jane, Yao, Cindy Q., Quintayo, Mary Anne, Yan, Fu, Haider, Syed, D’Costa, Alister, Brookes, Cassandra L., van de Velde, Cornelis J. H., Hasenburg, Annette, Kieback, Dirk G., Markopoulos, Christos, Dirix, Luc, Seynaeve, Caroline, Rea, Daniel, Boutros, Paul C., Bartlett, John M. S.
Published in NPJ breast cancer (15.02.2017)
Published in NPJ breast cancer (15.02.2017)
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Journal Article
A multicomponent structured health behaviour intervention to improve physical activity in long-distance HGV drivers: the SHIFT cluster RCT
Clemes, Stacy A, Varela-Mato, Veronica, Bodicoat, Danielle H, Brookes, Cassandra L, Chen, Yu-Ling, Cox, Edward, Edwardson, Charlotte L, Gray, Laura J, Guest, Amber, Johnson, Vicki, Munir, Fehmidah, Paine, Nicola J, Richardson, Gerry, Ruettger, Katharina, Sayyah, Mohsen, Sherry, Aron, Paola, Ana Suazo Di, Troughton, Jacqui, Walker, Simon, Yates, Thomas, King, James
Published in Public health research (Southampton, England) (01.11.2022)
Published in Public health research (Southampton, England) (01.11.2022)
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Journal Article
Rucaparib in patients with BAP1-deficient or BRCA1-deficient mesothelioma (MiST1): an open-label, single-arm, phase 2a clinical trial
Fennell, Dean A, King, Amy, Mohammed, Seid, Branson, Amy, Brookes, Cassandra, Darlison, Liz, Dawson, Alan G, Gaba, Aarti, Hutka, Margaret, Morgan, Bruno, Nicholson, Adrian, Richards, Cathy, Wells-Jordan, Peter, Murphy, Gavin James, Thomas, Anne
Published in The lancet respiratory medicine (01.06.2021)
Published in The lancet respiratory medicine (01.06.2021)
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Abemaciclib in patients with p16ink4A-deficient mesothelioma (MiST2): a single-arm, open-label, phase 2 trial
Fennell, Dean A, King, Amy, Mohammed, Seid, Greystoke, Alastair, Anthony, Sarah, Poile, Charlotte, Nusrat, Nada, Scotland, Molly, Bhundia, Vina, Branson, Amy, Brookes, Cassandra, Darlison, Liz, Dawson, Alan G, Gaba, Aarti, Hutka, Margaret, Morgan, Bruno, Bajaj, Amrita, Richards, Cathy, Wells-Jordan, Peter, Thomas, Anne, Fennell, Dean A., King, Amy, Greystoke, Alastair, Anthony, Sarah, Moody, Sam, Poille, Charlotte, Nusrat, Nada, Scotland, Molly, Bhundia, Vina, Branson, Amy, Brookes, Cassandra, Darlison, Liz, Dawson, Alan G., Gaba, Aarti, Hutka, Margaret, Morgan, Bruno, Bajaj, Amrita, Richards, Cathy, Wells-Jordan, Peter, Nicolson, Adrian, Underwood, Judith, Sodha-Ramdeen, Azmina, Cowley, Caroline, Barber, Shaun, Thomas, Anne
Published in The lancet oncology (01.03.2022)
Published in The lancet oncology (01.03.2022)
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Journal Article
Niraparib and dostarlimab efficacy in patients with platinum-sensitive relapsed mesothelioma: MIST5, a phase IIa clinical trial
Fennell, Dean Anthony, Branson, Amy, King, Amy, Poile, Charlotte, Barber, Shaun, Antoniou, Marina, Darlison, Liz, Taylor, Paul, Scotland, Molly, Belcher, Clare, Bajaj, Amrita, Morgan, Bruno, Brookes, Cassandra, Wells-Jordan, Peter, Dulloo, Sean
Published in Journal of clinical oncology (01.06.2024)
Published in Journal of clinical oncology (01.06.2024)
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