The Spongistatins: Architecturally Complex Natural Products-Part Two: Synthesis of the C(29-51) Subunit, Fragment Assembly, and Final Elaboration to (+)-Spongistatin 2
Smith III, Amos B., Lin, Qiyan, Doughty, Victoria A., Zhuang, Linghang, McBriar, Mark D., Kerns, Jeffrey K., Brook, Christopher S., Murase, Noriaki, Nakayama, Kiyoshi
Published in Angewandte Chemie International Edition (05.01.2001)
Published in Angewandte Chemie International Edition (05.01.2001)
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Journal Article
Spongipyran synthetic studies. Total synthesis of (+)-spongistatin 2
Smith, Amos B., Lin, Qiyan, Doughty, Victoria A., Zhuang, Linghang, McBriar, Mark D., Kerns, Jeffrey K., Boldi, Armen M., Murase, Noriaki, Moser, William H., Brook, Christopher S., Bennett, Clay S., Nakayama, Kiyoshi, Sobukawa, Masao, Lee Trout, Robert E.
Published in Tetrahedron (15.08.2009)
Published in Tetrahedron (15.08.2009)
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Journal Article
Spongistatin synthetic studies. 2. Assembly of the C(18–28) spiroketal
Smith, Amos B., Zhuang, Linghang, Brook, Christopher S., Lin, Qiyan, Moser, William H., Lee Trout, Robert E., Boldi, Armen M.
Published in Tetrahedron letters (15.12.1997)
Published in Tetrahedron letters (15.12.1997)
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Spongistatin synthetic studies. 1. Construction of a C(29–48) subtarget
Smith, Amos B., Zhuang, Linghang, Brook, Christopher S., Boldi, Armen M., McBriar, Mark D., Moser, William H., Murase, Noriaki, Nakayama, Kiyoshi, Verhoest, Patrick R., Lin, Qiyan
Published in Tetrahedron letters (15.12.1997)
Published in Tetrahedron letters (15.12.1997)
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Syntheses of Strychnos- and Aspidospermatan-Type Alkaloids. 6. Total Syntheses of (.+-.)-Echitamidine, (.+-.)-Alstogustine, (.+-.)-19-epi-Alstogustine, and (.+-.)-Akuammicine
Kuehne, Martin E, Xu, Feng, Brook, Christopher S
Published in Journal of organic chemistry (01.12.1994)
Published in Journal of organic chemistry (01.12.1994)
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Syntheses of Strychnos- and Aspidospermatan-Type Alkaloids. 7. Total Syntheses of Lagunamine, Isolagunamine, Condylocarpine, and Isocondylocarpine
Kuehne, Martin E, Brook, Christopher S, Frasier, Deborah A, Xu, Feng
Published in Journal of organic chemistry (01.03.1995)
Published in Journal of organic chemistry (01.03.1995)
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The Spongistatins: Architecturally Complex Natural Products-Part Two: Synthesis of the C(29-51) Subunit, Fragment Assembly, and Final Elaboration to (+)-Spongistatin 2 Financial support was provided by the National Institutes of Health (National Cancer Institute) through Grant CA-70329, a NIH Postdoctoral Fellowship to C.S.B., a Japan Society for Promotion of Science Fellowship to N.M., and a Royal Society Fulbright Fellowship to V.A.D. We also thank the Daiichi Pharmaceutical Co., Ltd, and the
Smith III, Amos B., Lin, Qiyan, Doughty, Victoria A., Zhuang, Linghang, McBriar, Mark D., Kerns, Jeffrey K., Brook, Christopher S., Murase, Noriaki, Nakayama, Kiyoshi
Published in Angewandte Chemie International Edition (05.01.2001)
Get full text
Published in Angewandte Chemie International Edition (05.01.2001)
Journal Article
Spongipyran synthetic studies. Total synthesis of (+)-spongistatin 2: 2008 Tetrahedron Prize for Creativity in Organic Chemistry. The Art of Synthesis: Methods, Strategies and Applications
SMITH, Amos B, QIYAN LIN, BENNETT, Clay S, NAKAYAMA, Kiyoshi, SOBUKAWA, Masao, LEE TROUT, Robert E, DOUGHTY, Victoria A, LINGHANG ZHUANG, MCBRIAR, Mark D, KERNS, Jeffrey K, BOLDI, Armen M, MURASE, Noriaki, MOSER, William H, BROOK, Christopher S
Published in Tetrahedron (2009)
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Published in Tetrahedron (2009)
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Solid-Phase Synthesis of a Combinatorial Array of 1,3-Bis(acylamino)-2-butanones, Inhibitors of the Cysteine Proteases Cathepsins K and L
Yamashita, Dennis S, Dong, Xiaoyang, Oh, Hye-Ja, Brook, Christopher S, Tomaszek, Thaddeus A, Szewczuk, Lawrence, Tew, David G, Veber, Daniel F
Published in Journal of combinatorial chemistry (01.05.1999)
Published in Journal of combinatorial chemistry (01.05.1999)
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Journal Article
Spongistatin synthetic studies. 3. Construction of the C(1–17) spiroketal
Smith, Amos B., Lin, Quyan, Nakayama, Kiyoshi, Boldi, Armen M., Brook, Christopher S., McBriar, Mark D., Moser, William H., Sobukawa, Masao, Zhuang, Linghang
Published in Tetrahedron letters (15.12.1997)
Published in Tetrahedron letters (15.12.1997)
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IL-8 RECEPTOR ANTAGONIST
BROOK CHRISTOPHER S, WEBB EDWARD C, JAKOB BUSCH-PETERSEN, RICHARD M GOODMAN
Year of Publication 27.03.2014
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Year of Publication 27.03.2014
Patent
IL-8 RECEPTOR ANTAGONIST
GOODMAN, RICHARD, M, BROOK, CHRISTOPHER, S, BUSCH-PETERSEN, JAKOB, WEBB, EDWARD, C
Year of Publication 02.10.2013
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Year of Publication 02.10.2013
Patent
The Spongistatins: Architecturally Complex Natural Products-Part Two: Synthesis of the C(29-51) Subunit, Fragment Assembly, and Final Elaboration to (+)-Spongistatin 2
Smith III, Amos B., Lin, Qiyan, Doughty, Victoria A., Zhuang, Linghang, McBriar, Mark D., Kerns, Jeffrey K., Brook, Christopher S., Murase, Noriaki, Nakayama, Kiyoshi
Published in Angewandte Chemie (05.01.2001)
Published in Angewandte Chemie (05.01.2001)
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Journal Article