Single-cell transcriptomics identifies an effectorness gradient shaping the response of CD4+ T cells to cytokines
Cano-Gamez, Eddie, Soskic, Blagoje, Roumeliotis, Theodoros I., So, Ernest, Smyth, Deborah J., Baldrighi, Marta, Willé, David, Nakic, Nikolina, Esparza-Gordillo, Jorge, Larminie, Christopher G. C., Bronson, Paola G., Tough, David F., Rowan, Wendy C., Choudhary, Jyoti S., Trynka, Gosia
Published in Nature communications (14.04.2020)
Published in Nature communications (14.04.2020)
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Immune disease risk variants regulate gene expression dynamics during CD4+ T cell activation
Soskic, Blagoje, Cano-Gamez, Eddie, Smyth, Deborah J., Ambridge, Kirsty, Ke, Ziying, Matte, Julie C., Bossini-Castillo, Lara, Kaplanis, Joanna, Ramirez-Navarro, Lucia, Lorenc, Anna, Nakic, Nikolina, Esparza-Gordillo, Jorge, Rowan, Wendy, Wille, David, Tough, David F., Bronson, Paola G., Trynka, Gosia
Published in Nature genetics (01.06.2022)
Published in Nature genetics (01.06.2022)
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Chromatin activity at GWAS loci identifies T cell states driving complex immune diseases
Soskic, Blagoje, Cano-Gamez, Eddie, Smyth, Deborah J., Rowan, Wendy C., Nakic, Nikolina, Esparza-Gordillo, Jorge, Bossini-Castillo, Lara, Tough, David F., Larminie, Christopher G. C., Bronson, Paola G., Willé, David, Trynka, Gosia
Published in Nature genetics (01.10.2019)
Published in Nature genetics (01.10.2019)
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Systematic Mendelian randomization using the human plasma proteome to discover potential therapeutic targets for stroke
Chen, Lingyan, Peters, James E., Prins, Bram, Persyn, Elodie, Traylor, Matthew, Surendran, Praveen, Karthikeyan, Savita, Yonova-Doing, Ekaterina, Di Angelantonio, Emanuele, Roberts, David J., Watkins, Nicholas A., Ouwehand, Willem H., Danesh, John, Lewis, Cathryn M., Bronson, Paola G., Markus, Hugh S., Burgess, Stephen, Butterworth, Adam S., Howson, Joanna M. M.
Published in Nature communications (17.10.2022)
Published in Nature communications (17.10.2022)
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Neurology-related protein biomarkers are associated with cognitive ability and brain volume in older age
Harris, Sarah E., Cox, Simon R., Bell, Steven, Marioni, Riccardo E., Prins, Bram P., Pattie, Alison, Corley, Janie, Muñoz Maniega, Susana, Valdés Hernández, Maria, Morris, Zoe, John, Sally, Bronson, Paola G., Tucker-Drob, Elliot M., Starr, John M., Bastin, Mark E., Wardlaw, Joanna M., Butterworth, Adam S., Deary, Ian J.
Published in Nature communications (10.02.2020)
Published in Nature communications (10.02.2020)
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The genetics of type I interferon in systemic lupus erythematosus
Bronson, Paola G, Chaivorapol, Christina, Ortmann, Ward, Behrens, Timothy W, Graham, Robert R
Published in Current opinion in immunology (01.10.2012)
Published in Current opinion in immunology (01.10.2012)
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A whole-genome sequence study identifies genetic risk factors for neuromyelitis optica
Estrada, Karol, Whelan, Christopher W., Zhao, Fengmei, Bronson, Paola, Handsaker, Robert E., Sun, Chao, Carulli, John P., Harris, Tim, Ransohoff, Richard M., McCarroll, Steven A., Day-Williams, Aaron G., Greenberg, Benjamin M., MacArthur, Daniel G.
Published in Nature communications (16.05.2018)
Published in Nature communications (16.05.2018)
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Genome-wide study of longitudinal brain imaging measures of multiple sclerosis progression across six clinical trials
Loomis, Stephanie J., Sadhu, Nilanjana, Fisher, Elizabeth, Gafson, Arie R., Huang, Yunfeng, Yang, Chengran, Hughes, Emily E., Marshall, Eric, Herman, Ann, John, Sally, Runz, Heiko, Jia, Xiaoming, Bhangale, Tushar, Bronson, Paola G.
Published in Scientific reports (31.08.2023)
Published in Scientific reports (31.08.2023)
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A higher burden of multiple sclerosis genetic risk confers an earlier onset
Misicka, Elina, Davis, Mary F, Kim, Woori, Brugger, Steven W, Beales, Jeremy, Loomis, Stephanie, Bronson, Paola G, Briggs, Farren Bs
Published in Multiple sclerosis (01.07.2022)
Published in Multiple sclerosis (01.07.2022)
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Systematic single-variant and gene-based association testing of thousands of phenotypes in 394,841 UK Biobank exomes
Karczewski, Konrad J., Solomonson, Matthew, Chao, Katherine R., Goodrich, Julia K., Tiao, Grace, Lu, Wenhan, Riley-Gillis, Bridget M., Tsai, Ellen A., Kim, Hye In, Zheng, Xiuwen, Rahimov, Fedik, Esmaeeli, Sahar, Grundstad, A. Jason, Reppell, Mark, Waring, Jeff, Jacob, Howard, Sexton, David, Bronson, Paola G., Chen, Xing, Hu, Xinli, Goldstein, Jacqueline I., King, Daniel, Vittal, Christopher, Poterba, Timothy, Palmer, Duncan S., Churchhouse, Claire, Howrigan, Daniel P., Zhou, Wei, Watts, Nicholas A., Nguyen, Kevin, Nguyen, Huy, Mason, Cara, Farnham, Christopher, Tolonen, Charlotte, Gauthier, Laura D., Gupta, Namrata, MacArthur, Daniel G., Rehm, Heidi L., Seed, Cotton, Philippakis, Anthony A., Daly, Mark J., Davis, J. Wade, Runz, Heiko, Miller, Melissa R., Neale, Benjamin M.
Published in Cell genomics (14.09.2022)
Published in Cell genomics (14.09.2022)
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Increased DNA methylation of SLFN12 in CD4+ and CD8+ T cells from multiple sclerosis patients
Rhead, Brooke, Brorson, Ina S, Berge, Tone, Adams, Cameron, Quach, Hong, Moen, Stine Marit, Berg-Hansen, Pål, Celius, Elisabeth Gulowsen, Sangurdekar, Dipen P, Bronson, Paola G, Lea, Rodney A, Burnard, Sean, Maltby, Vicki E, Scott, Rodney J, Lechner-Scott, Jeannette, Harbo, Hanne F, Bos, Steffan D, Barcellos, Lisa F
Published in PloS one (2018)
Published in PloS one (2018)
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STXBP6 and B3GNT6 Genes are Associated With Selective IgA Deficiency
Lim, Che Kang, Bronson, Paola G, Varade, Jezabel, Behrens, Timothy W, Hammarström, Lennart
Published in Frontiers in genetics (17.12.2021)
Published in Frontiers in genetics (17.12.2021)
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Genome-wide association study identifies kallikrein 5 in type 2 inflammation-low asthma
Jackman, Janet K., Stockwell, Amy, Choy, David F., Xie, Markus M., Lu, Peipei, Jia, Guiquan, Li, Hong, Abbas, Alexander R., Bronson, Paola G., Lin, Wei-Yu, Chiu, Cecilia P.C., Maun, Henry R., Roose-Girma, Merone, Tam, Lucinda, Zhang, Juan, Modrusan, Zora, Graham, Robert R., Behrens, Timothy W., White, Steven R., Naureckas, Ted, Ober, Carole, Ferreira, Manuel, Sedlacek, Radislav, Wu, Jiansheng, Lee, Wyne P., Lazarus, Robert A., Koerber, James T., Arron, Joseph R., Yaspan, Brian L., Yi, Tangsheng
Published in Journal of allergy and clinical immunology (01.10.2022)
Published in Journal of allergy and clinical immunology (01.10.2022)
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Common variants at PVT1, ATG13–AMBRA1, AHI1 and CLEC16A are associated with selective IgA deficiency
Bronson, Paola G, Chang, Diana, Bhangale, Tushar, Seldin, Michael F, Ortmann, Ward, Ferreira, Ricardo C, Urcelay, Elena, Pereira, Luis Fernández, Martin, Javier, Plebani, Alessandro, Lougaris, Vassilios, Friman, Vanda, Freiberger, Tomáš, Litzman, Jiri, Thon, Vojtech, Pan-Hammarström, Qiang, Hammarström, Lennart, Graham, Robert R, Behrens, Timothy W
Published in Nature genetics (01.11.2016)
Published in Nature genetics (01.11.2016)
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Adaptive and Innate Immunity Are Key Drivers of Age at Onset of Multiple Sclerosis
Misicka, Elina, Huang, Yunfeng, Loomis, Stephanie, Sadhu, Nilanjana, Fisher, Elizabeth, Gafson, Arie, Runz, Heiko, Tsai, Ellen, Jia, Xiaoming, Herman, Ann, Bronson, Paola G, Bhangale, Tushar, Briggs, Farren B
Published in Neurology. Genetics (01.06.2024)
Published in Neurology. Genetics (01.06.2024)
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Genetic Study of Severe Prolonged Lymphopenia in Multiple Sclerosis Patients Treated With Dimethyl Fumarate
Sangurdekar, Dipen, Sun, Chao, McLaughlin, Helen, Ayling-Rouse, Katherine, Allaire, Normand E., Penny, Michelle A., Bronson, Paola G.
Published in Frontiers in genetics (04.11.2019)
Published in Frontiers in genetics (04.11.2019)
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CIITA variation in the presence of HLA-DRB11501 increases risk for multiple sclerosis
Bronson, Paola G., Caillier, Stacy, Ramsay, Patricia P., McCauley, Jacob L., Zuvich, Rebecca L., De Jager, Philip L., Rioux, John D., Ivinson, Adrian J., Compston, Alastair, Hafler, David A., Sawcer, Stephen J., Pericak-Vance, Margaret A., Haines, Jonathan L., Hauser, Stephen L., Oksenberg, Jorge R., Barcellos, Lisa F.
Published in Human molecular genetics (01.06.2010)
Published in Human molecular genetics (01.06.2010)
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Inhibition of MRP1 Induces Fetal Hemoglobin through NRF2 Activation to Protect Human Erythroid Cells from Sickling
Hara, Yannis, Kawabata, Emily, Lemgart, Viktor T., Bronson, Paola G., Hicks, Alexandra, Krishnamoorthy, Sriram, Watkins, Nicholas, Peters, Robert, Roberts, David J., Di Angelantonio, Emanuele, Danesh, John, Astle, William, Paul, Dirk S., Lessard, Samuel, Butterworth, Adam S.
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Identification of Novel Variants Associated with Fetal Hemoglobin Levels in Healthy Donors (the INTERVAL study)
Kawabata, Emily, Lessard, Samuel, Paul, Dirk, Bronson, Paola G, Peters, Robert, Krishnamoorthy, Sriram, Astle, William, Butterworth, Adam
Published in Blood (13.11.2019)
Published in Blood (13.11.2019)
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