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Bromberg, Kenneth D, Mitchell, Taylor R H, Upadhyay, Anup K, Jakob, Clarissa G, Jhala, Manisha A, Comess, Kenneth M, Lasko, Loren M, Li, Conglei, Tuzon, Creighton T, Dai, Yujia, Li, Fengling, Eram, Mohammad S, Nuber, Alexander, Soni, Niru B, Manaves, Vlasios, Algire, Mikkel A, Sweis, Ramzi F, Torrent, Maricel, Schotta, Gunnar, Sun, Chaohong, Michaelides, Michael R, Shoemaker, Alex R, Arrowsmith, Cheryl H, Brown, Peter J, Santhakumar, Vijayaratnam, Martin, Alberto, Rice, Judd C, Chiang, Gary G, Vedadi, Masoud, Barsyte-Lovejoy, Dalia, Pappano, William N
Published in Nature chemical biology (01.03.2017)
Published in Nature chemical biology (01.03.2017)
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Cannabinoid 1 Receptor and Interleukin-6 Receptor Together Induce Integration of Protein Kinase and Transcription Factor Signaling to Trigger Neurite Outgrowth
Zorina, Yana, Iyengar, Ravi, Bromberg, Kenneth D.
Published in The Journal of biological chemistry (08.01.2010)
Published in The Journal of biological chemistry (08.01.2010)
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Discovery of a Potent and Selective Covalent p300/CBP Inhibitor
Mastracchio, Anthony, Lai, Chunqiu, Digiammarino, Enrico, Ready, Damien B, Lasko, Loren M, Bromberg, Kenneth D, McClellan, William J, Montgomery, Debra, Manaves, Vlasios, Shaw, Bailin, Algire, Mikkel, Patterson, Melanie J, Sun, Chaohong C, Rosenberg, Saul, Lai, Albert, Michaelides, Michael R
Published in ACS medicinal chemistry letters (13.05.2021)
Published in ACS medicinal chemistry letters (13.05.2021)
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Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours
Lasko, Loren M., Jakob, Clarissa G., Edalji, Rohinton P., Qiu, Wei, Montgomery, Debra, Digiammarino, Enrico L., Hansen, T. Matt, Risi, Roberto M., Frey, Robin, Manaves, Vlasios, Shaw, Bailin, Algire, Mikkel, Hessler, Paul, Lam, Lloyd T., Uziel, Tamar, Faivre, Emily, Ferguson, Debra, Buchanan, Fritz G., Martin, Ruth L., Torrent, Maricel, Chiang, Gary G., Karukurichi, Kannan, Langston, J. William, Weinert, Brian T., Choudhary, Chunaram, de Vries, Peter, Kluge, Arthur F., Patane, Michael A., Van Drie, John H., Wang, Ce, McElligott, David, Kesicki, Ed, Marmorstein, Ronen, Sun, Chaohong, Cole, Philip A., Rosenberg, Saul H., Michaelides, Michael R., Lai, Albert, Bromberg, Kenneth D.
Published in Nature (London) (05.10.2017)
Published in Nature (London) (05.10.2017)
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Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition
Hogg, Simon J., Motorna, Olga, Cluse, Leonie A., Johanson, Timothy M., Coughlan, Hannah D., Raviram, Ramya, Myers, Robert M., Costacurta, Matteo, Todorovski, Izabela, Pijpers, Lizzy, Bjelosevic, Stefan, Williams, Tobias, Huskins, Shannon N., Kearney, Conor J., Devlin, Jennifer R., Fan, Zheng, Jabbari, Jafar S., Martin, Ben P., Fareh, Mohamed, Kelly, Madison J., Dupéré-Richer, Daphné, Sandow, Jarrod J., Feran, Breon, Knight, Deborah, Khong, Tiffany, Spencer, Andrew, Harrison, Simon J., Gregory, Gareth, Wickramasinghe, Vihandha O., Webb, Andrew I., Taberlay, Phillippa C., Bromberg, Kenneth D., Lai, Albert, Papenfuss, Anthony T., Smyth, Gordon K., Allan, Rhys S., Licht, Jonathan D., Landau, Dan A., Abdel-Wahab, Omar, Shortt, Jake, Vervoort, Stephin J., Johnstone, Ricky W.
Published in Molecular cell (20.05.2021)
Published in Molecular cell (20.05.2021)
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Discovery of Potent Azetidine-Benzoxazole MerTK Inhibitors with In Vivo Target Engagement
Frey, Robin R., Jana, Navendu, Gorman, Jacob V., Wang, Jin, Smith, Heath A., Bromberg, Kenneth D., Thakur, Ashish, Doktor, Stella Z., Indulkar, Anura S., Jakob, Clarissa G., Upadhyay, Anup K., Qiu, Wei, Manaves, Vlasios, Gambino, Frank, Valentino, Stephen A., Montgomery, Debra, Zhou, Yebin, Li, Tao, Buchanan, Fritz G., Ferguson, Debra C., Kurnick, Matthew D., Kapecki, Nicolas, Lai, Albert, Michaelides, Michael R., Penning, Thomas D.
Published in Journal of medicinal chemistry (10.10.2024)
Published in Journal of medicinal chemistry (10.10.2024)
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Discovery of A‑910, a Highly Potent and Orally Bioavailable Dual MerTK/Axl-Selective Tyrosine Kinase Inhibitor
Yu, Yiyun, Jang, Miyeon, Miyashiro, Julie, Clark, Richard F., Zhu, Gui-Dong, Gong, Jane, Dai, Yujia, Frey, Robin R., Penning, Thomas D., Kim, Hadong, Lee, Hyung Ki, Kim, Jin Kwan, Ryu, Ki Moon, Park, Seong Jin, Yoon, Taeyoung, Li, Tao, Kurnick, Matthew D., Kapecki, Nicolas J., Li, Leiming, Gorman, Jacob V., Montgomery, Debra A., Manaves, Vlasios, Bromberg, Kenneth D., Doktor, Stella Z., Thakur, Ashish, Wang, Jin, Smith, Heath A., Buchanan, Fritz G., Ferguson, Debra C., Torrent, Maricel, Jakob, Clarissa G., Qiu, Wei, Upadhyay, Anup K., Martin, Ruth L., Lai, Albert, Michaelides, Michael R.
Published in Journal of medicinal chemistry (10.10.2024)
Published in Journal of medicinal chemistry (10.10.2024)
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Time-Resolved Analysis Reveals Rapid Dynamics and Broad Scope of the CBP/p300 Acetylome
Weinert, Brian T., Narita, Takeo, Satpathy, Shankha, Srinivasan, Balaji, Hansen, Bogi K., Schölz, Christian, Hamilton, William B., Zucconi, Beth E., Wang, Wesley W., Liu, Wenshe R., Brickman, Joshua M., Kesicki, Edward A., Lai, Albert, Bromberg, Kenneth D., Cole, Philip A., Choudhary, Chunaram
Published in Cell (28.06.2018)
Published in Cell (28.06.2018)
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Discovery of spirohydantoins as selective, orally bioavailable inhibitors of p300/CBP histone acetyltransferases
Ji, Zhiqin, Clark, Richard F., Bhat, Vikram, Matthew Hansen, T., Lasko, Loren M., Bromberg, Kenneth D., Manaves, Vlasios, Algire, Mikkel, Martin, Ruth, Qiu, Wei, Torrent, Maricel, Jakob, Clarissa G., Liu, Hong, Cole, Philip A., Marmorstein, Ronen, Kesicki, Edward A., Lai, Albert, Michaelides, Michael R.
Published in Bioorganic & medicinal chemistry letters (01.05.2021)
Published in Bioorganic & medicinal chemistry letters (01.05.2021)
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JAMP, a Jun N-Terminal Kinase 1 (JNK1)-Associated Membrane Protein, Regulates Duration of JNK Activity
Kadoya, Takayuki, Khurana, Ashwani, Tcherpakov, Marianna, Bromberg, Kenneth D., Didier, Christine, Broday, Limor, Asahara, Toshimasa, Bhoumik, Anindita, Ronai, Ze'ev
Published in Molecular and Cellular Biology (01.10.2005)
Published in Molecular and Cellular Biology (01.10.2005)
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Discovery of Spiro Oxazolidinediones as Selective, Orally Bioavailable Inhibitors of p300/CBP Histone Acetyltransferases
Michaelides, Michael R, Kluge, Arthur, Patane, Michael, Van Drie, John H, Wang, Ce, Hansen, T. Matthew, Risi, Roberto M, Mantei, Robert, Hertel, Carmen, Karukurichi, Kannan, Nesterov, Alexandre, McElligott, David, de Vries, Peter, Langston, J. William, Cole, Philip A, Marmorstein, Ronen, Liu, Hong, Lasko, Loren, Bromberg, Kenneth D, Lai, Albert, Kesicki, Edward A
Published in ACS medicinal chemistry letters (11.01.2018)
Published in ACS medicinal chemistry letters (11.01.2018)
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The ER-bound RING finger protein 5 (RNF5/RMA1) causes degenerative myopathy in transgenic mice and is deregulated in inclusion body myositis
Delaunay, Agnès, Bromberg, Kenneth D, Hayashi, Yukiko, Mirabella, Massimiliano, Burch, Denise, Kirkwood, Brian, Serra, Carlo, Malicdan, May C, Mizisin, Andrew P, Morosetti, Roberta, Broccolini, Aldobrando, Guo, Ling T, Jones, Stephen N, Lira, Sergio A, Puri, Pier Lorenzo, Shelton, G Diane, Ronai, Ze'ev
Published in PloS one (13.02.2008)
Published in PloS one (13.02.2008)
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Distinct modulation of IFNγ-induced transcription by BET bromodomain and catalytic P300/CBP inhibition in breast cancer
Hogg, Simon J., Motorna, Olga, Kearney, Conor J., Derrick, Emily B., House, Imran G., Todorovski, Izabela, Kelly, Madison J., Zethoven, Magnus, Bromberg, Kenneth D., Lai, Albert, Beavis, Paul A., Shortt, Jake, Johnstone, Ricky W., Vervoort, Stephin J.
Published in Clinical epigenetics (28.07.2022)
Published in Clinical epigenetics (28.07.2022)
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Author Correction: Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours
Lasko, Loren M., Jakob, Clarissa G., Edalji, Rohinton P., Qiu, Wei, Montgomery, Debra, Digiammarino, Enrico L., Hansen, T. Matt, Risi, Roberto M., Frey, Robin, Manaves, Vlasios, Shaw, Bailin, Algire, Mikkel, Hessler, Paul, Lam, Lloyd T., Uziel, Tamar, Faivre, Emily, Ferguson, Debra, Buchanan, Fritz G., Martin, Ruth L., Torrent, Maricel, Chiang, Gary G., Karukurichi, Kannan, Langston, J. William, Weinert, Brian T., Choudhary, Chunaram, de Vries, Peter, Kluge, Arthur F., Patane, Michael A., Van Drie, John H., Wang, Ce, McElligott, David, Kesicki, Edward A., Marmorstein, Ronen, Sun, Chaohong, Cole, Philip A., Rosenberg, Saul H., Michaelides, Michael R., Lai, Albert, Bromberg, Kenneth D.
Published in Nature (London) (01.06.2018)
Published in Nature (London) (01.06.2018)
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Increased expression of the E3 ubiquitin ligase RNF5 is associated with decreased survival in breast cancer
BROMBERG, Kenneth D, KLUGER, Harriet M, DELAUNAY, Agnes, ABBAS, Sabiha, DIVITO, Kyle A, KRAJEWSKI, Stan, RONAI, Zeev
Published in Cancer research (Chicago, Ill.) (01.09.2007)
Published in Cancer research (Chicago, Ill.) (01.09.2007)
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1,4-Benzoquinone Is a Topoisomerase II Poison
Lindsey, R. Hunter, Bromberg, Kenneth D, Felix, Carolyn A, Osheroff, Neil
Published in Biochemistry (Easton) (15.06.2004)
Published in Biochemistry (Easton) (15.06.2004)
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Pyrimidine-Based Tricyclic Molecules as Potent and Orally Efficacious Inhibitors of Wee1 Kinase
Tong, Yunsong, Torrent, Maricel, Florjancic, Alan S, Bromberg, Kenneth D, Buchanan, Fritz G, Ferguson, Debra C, Johnson, Eric F, Lasko, Loren M, Maag, David, Merta, Philip J, Olson, Amanda M, Osterling, Donald J, Soni, Nirupama, Shoemaker, Alexander R, Penning, Thomas D
Published in ACS medicinal chemistry letters (08.01.2015)
Published in ACS medicinal chemistry letters (08.01.2015)
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