Discovery of Rogaratinib (BAY 1163877): a pan‐FGFR Inhibitor
Collin, Marie‐Pierre, Lobell, Mario, Hübsch, Walter, Brohm, Dirk, Schirok, Hartmut, Jautelat, Rolf, Lustig, Klemens, Bömer, Ulf, Vöhringer, Verena, Héroult, Mélanie, Grünewald, Sylvia, Hess‐Stumpp, Holger
Published in ChemMedChem (06.03.2018)
Published in ChemMedChem (06.03.2018)
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Journal Article
Abstract 4332: Discovery of BAY 1163877 - A pan-FGFR inhibitor: De novo structure-based design and lead optimization of benzothiophenyl-pyrrolotriazines
Collin, Marie-Pierre L., Lobell, Mario, Huebsch, Walter, Brohm, Dirk, Héroult, Mélanie, Lustig, Klemens, Gruenewald, Sylvia, Boemer, Ulf, Jautelat, Rolf, Hess-Stump, Holger, Jaroch, Stefan, Brands, Michael, Ziegelbauer, Karl
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Natural Products Are Biologically Validated Starting Points in Structural Space for Compound Library Development: Solid-Phase Synthesis of Dysidiolide-Derived Phosphatase Inhibitors
Brohm, Dirk, Metzger, Susanne, Bhargava, Ajay, Müller, Oliver, Lieb, Folker, Waldmann, Herbert
Published in Angewandte Chemie (International ed.) (18.01.2002)
Published in Angewandte Chemie (International ed.) (18.01.2002)
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Abstract 1739: Preclinical profile of BAY 1163877 - a selective pan-FGFR inhibitor in phase 1 clinical trial
Heroult, Melanie, Ellinghaus, Peter, Sieg, Christian, Brohm, Dirk, Gruenewald, Sylvia, Collin, Marie-Pierre, Boemer, Ulf, Lobell, Mario, Huebsch, Walter, Ocker, Matthias, Ince, Stuart, Haegebarth, Andrea, Jautelat, Rolf, Hess-Stumpp, Holger, Brands, Michael, Ziegelbauer, Karl
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
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An efficient and inexpensive scavenger resin for Grubbs’ catalyst
Westhus, Markus, Gonthier, Elisabeth, Brohm, Dirk, Breinbauer, Rolf
Published in Tetrahedron letters (05.04.2004)
Published in Tetrahedron letters (05.04.2004)
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Discovery of substituted N-phenylbenzenesulphonamides as a novel class of non-nucleoside hepatitis C virus polymerase inhibitors
May, Marina M., Brohm, Dirk, Harrenga, Axel, Marquardt, Tobias, Riedl, Bernd, Kreuter, Joerg, Zimmermann, Holger, Ruebsamen-Schaeff, Helga, Urban, Andreas
Published in Antiviral research (01.08.2012)
Published in Antiviral research (01.08.2012)
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