The role of genetics and epigenetics in the pathogenesis of systemic sclerosis
Broen, Jasper C. A., Radstake, Timothy R. D. J., Rossato, Marzia
Published in Nature reviews. Rheumatology (01.11.2014)
Published in Nature reviews. Rheumatology (01.11.2014)
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Journal Article
Identification of CSK as a systemic sclerosis genetic risk factor through Genome Wide Association Study follow-up
MARTIN, Jose-Ezequiel, BROEN, Jasper C, ORTEGO-CENTENO, Norberto, GONZALEZ-GAY, Miguel A, GARCIA-HERNANDEZ, Francisco J, DE LA PENA, Paloma Garcia, CARREIRA, Patricia, VOSKUYL, Alexandre E, SCHUERWEGH, Annemie J, RIEL, Piet L. C. M. Van, KREUTER, Alexander, WITTE, Torsten, CARMONA, F. David, RIEMEKASTEN, Gabriella, AIRO, Paolo, SCORZA, Raffaella, LUNARDI, Claudio, HUNZELMANN, Nicolas, DISTLER, Jörg H. W, BERETTA, Lorenzo, LAAR, Jacob Van, MENG MAY CHEE, WORTHINGTON, Jane, TERUEL, Maria, HERRICK, Ariane, DENTON, Christopher, TAN, Filemon K, ARNETT, Frank C, ASSASSI, Shervin, FONSECA, Carmen, MAYES, Maureen D, RADSTAKE, Timothy R. D. J, KOELEMAN, Bobby P. C, MARTIN, Javier, SIMEON, Carmen P, VONK, Madelon C, VAN'T SLOT, Ruben, RODRIGUEZ-RODRIGUEZ, Luis, VICENTE, Esther, FONOLLOSA, Vicente
Published in Human molecular genetics (15.06.2012)
Published in Human molecular genetics (15.06.2012)
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Journal Article
Unraveling IFN-I response dynamics and TNF crosstalk in the pathophysiology of systemic lupus erythematosus
Van Eyndhoven, Laura C, Chouri, Eleni, Matos, Catarina I, Pandit, Aridaman, Radstake, Timothy R D J, Broen, Jasper C A, Singh, Abhyudai, Tel, Jurjen
Published in Frontiers in immunology (26.03.2024)
Published in Frontiers in immunology (26.03.2024)
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Journal Article
Gout Is a Chronic Inflammatory Disease in Which High Levels of Interleukin‐8 (CXCL8), Myeloid‐Related Protein 8/Myeloid‐Related Protein 14 Complex, and an Altered Proteome Are Associated With Diabetes Mellitus and Cardiovascular Disease
Kienhorst, Laura B. E., van Lochem, Ellen, Kievit, Wietske, Dalbeth, Nicola, Merriman, Marilyn E., Phipps‐Green, Amanda, Loof, Arnoud, van Heerde, Waander, Vermeulen, Sita, Stamp, Lisa K., van Koolwijk, Elly, de Graaf, Jacqueline, Holzinger, Dirk, Roth, Johannes, Janssens, Hein J. E. M., Merriman, Tony R., Broen, Jasper C. A., Janssen, Matthijs, Radstake, Timothy R. D. J.
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.12.2015)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.12.2015)
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Journal Article
Aberrant leukocyte telomere length in Birdshot Uveitis
Vazirpanah, Nadia, Verhagen, Fleurieke H, Rothova, Anna, Missotten, Tom O A R, van Velthoven, Mirjam, Den Hollander, Anneke I, Hoyng, Carel B, Radstake, Timothy R D J, Broen, Jasper C A, Kuiper, Jonas J W
Published in PloS one (01.05.2017)
Published in PloS one (01.05.2017)
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Journal Article
Skewed X chromosomal inactivation impacts T regulatory cell function in systemic sclerosis
Broen, Jasper C A, Wolvers-Tettero, Ingrid L M, Geurts-van Bon, Lenny, Vonk, Madelon C, Coenen, Marieke J H, Lafyatis, Robert, Radstake, Timothy R D J, Langerak, Anton W
Published in Annals of the rheumatic diseases (01.12.2010)
Published in Annals of the rheumatic diseases (01.12.2010)
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Journal Article
Quantification of Double Stranded DNA Breaks and Telomere Length as Proxies for Corneal Damage and Replicative Stress in Human Keratoconus Corneas
Wisse, Robert P L, Kuiper, Jonas J W, Radstake, Timothy R D, Broen, Jasper C A
Published in Translational vision science & technology (01.07.2019)
Published in Translational vision science & technology (01.07.2019)
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Journal Article
Low RUNX3 expression alters dendritic cell function in patients with systemic sclerosis and contributes to enhanced fibrosis
Affandi, Alsya J, Carvalheiro, Tiago, Ottria, Andrea, Broen, Jasper CA, Bossini-Castillo, Lara, Tieland, Ralph G, Bon, Lenny van, Chouri, Eleni, Rossato, Marzia, Mertens, Jorre S, Garcia, Samuel, Pandit, Aridaman, de Kroon, Laurie MG, Christmann, Romy B, Martin, Javier, van Roon, Joel AG, Radstake, Timothy RDJ, Marut, Wioleta
Published in Annals of the rheumatic diseases (01.09.2019)
Published in Annals of the rheumatic diseases (01.09.2019)
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Journal Article
PD-1+CD8+ T cells are clonally expanding effectors in human chronic inflammation
Petrelli, Alessandra, Mijnheer, Gerdien, Hoytema van Konijnenburg, David P, van der Wal, Maria M, Giovannone, Barbara, Mocholi, Enric, Vazirpanah, Nadia, Broen, Jasper C, Hijnen, Dirkjan, Oldenburg, Bas, Coffer, Paul J, Vastert, Sebastian J, Prakken, Berent J, Spierings, Eric, Pandit, Aridaman, Mokry, Michal, van Wijk, Femke
Published in The Journal of clinical investigation (01.10.2018)
Published in The Journal of clinical investigation (01.10.2018)
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Journal Article
Polymorphisms in the interleukin 4, interleukin 13, and corresponding receptor genes are not associated with systemic sclerosis and do not influence gene expression
Broen, Jasper C A, Dieude, Phillipe, Vonk, Madelon C, Beretta, Lorenzo, Carmona, Francisco D, Herrick, Ariane, Worthington, Jane, Hunzelmann, Nicholas, Riemekasten, Gabriela, Kiener, Hans, Scorza, Rafaella, Simeon, Carmen P, Fonollosa, Vicent, Carreira, Patricia, Ortego-Centeno, Norberto, Gonzalez-Gay, Miguel A, Airo', Paolo, Coenen, Marieke J, Tsang, Kelly, Aliprantis, Antonios O, Martin, Javier, Allanore, Yannick, Radstake, Timothy R D J
Published in Journal of rheumatology (01.01.2012)
Published in Journal of rheumatology (01.01.2012)
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Journal Article
Longitudinal changes of telomere length and epigenetic age related to traumatic stress and post-traumatic stress disorder
Boks, Marco P, Mierlo, Hans C. van, Rutten, Bart P.F, Radstake, Timothy R.D.J, De Witte, Lot, Geuze, Elbert, Horvath, Steve, Schalkwyk, Leonard C, Vinkers, Christiaan H, Broen, Jasper C.A, Vermetten, Eric
Published in Psychoneuroendocrinology (01.01.2015)
Published in Psychoneuroendocrinology (01.01.2015)
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Journal Article
The immunologic etiology of psychiatric manifestations in systemic lupus erythematosus: A narrative review on the role of the blood brain barrier, antibodies, cytokines and chemokines
Deijns, Sander J., Broen, Jasper C.A., Kruyt, Nyika D., Schubart, Chris D., Andreoli, Laura, Tincani, Angela, Limper, Maarten
Published in Autoimmunity reviews (01.08.2020)
Published in Autoimmunity reviews (01.08.2020)
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Journal Article
B-cells and schizophrenia: A promising link or a finding lost in translation?
van Mierlo, Hans C., Broen, Jasper C.A., Kahn, René S., de Witte, Lot D.
Published in Brain, behavior, and immunity (01.10.2019)
Published in Brain, behavior, and immunity (01.10.2019)
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Journal Article
mTOR inhibition by metformin impacts monosodium urate crystal–induced inflammation and cell death in gout: a prelude to a new add-on therapy?
Vazirpanah, Nadia, Ottria, Andrea, van der Linden, Maarten, Wichers, Catharina G K, Schuiveling, Mark, van Lochem, Ellen, Phipps-Green, Amanda, Merriman, Tony, Zimmermann, Maili, Jansen, Matthijs, Radstake, Timothy R D J, Broen, Jasper C A
Published in Annals of the rheumatic diseases (01.05.2019)
Published in Annals of the rheumatic diseases (01.05.2019)
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Journal Article
Accelerated telomere shortening in rheumatic diseases: cause or consequence?
Dehbi, Amina ZA, Radstake, Timothy RDJ, Broen, Jasper CA
Published in Expert review of clinical immunology (01.12.2013)
Published in Expert review of clinical immunology (01.12.2013)
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Journal Article
Association of MicroRNA‐618 Expression With Altered Frequency and Activation of Plasmacytoid Dendritic Cells in Patients With Systemic Sclerosis
Rossato, Marzia, Affandi, Alsya J., Thordardottir, Soley, Wichers, Catharina G. K., Cossu, Marta, Broen, Jasper C. A., Moret, Frederique M., Bossini‐Castillo, Lara, Chouri, Eleni, van Bon, Lenny, Wolters, Femke, Marut, Wioleta, van der Kroef, Maarten, Silva‐Cardoso, Sandra, Bekker, Cornelis P. J., Dolstra, Harry, van Laar, Jacob M., Martin, Javier, van Roon, Joel A. G., Reedquist, Kris A., Beretta, Lorenzo, Radstake, Timothy R. D. J.
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.09.2017)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.09.2017)
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Journal Article
Neonatal thymectomy reveals differentiation and plasticity within human naive T cells
van den Broek, Theo, Delemarre, Eveline M, Janssen, Willemijn J M, Nievelstein, Rutger A J, Broen, Jasper C, Tesselaar, Kiki, Borghans, Jose A M, Nieuwenhuis, Edward E S, Prakken, Berent J, Mokry, Michal, Jansen, Nicolaas J G, van Wijk, Femke
Published in The Journal of clinical investigation (01.03.2016)
Published in The Journal of clinical investigation (01.03.2016)
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Journal Article
Overlapping gene expression profiles indicative of antigen processing and the interferon pathway characterize inflammatory fibrotic skin diseases
Limpers, Annelies, van Royen-Kerkhof, Annet, van Roon, Joel AG, Radstake, TimothyRDJ, Broen, Jasper CA
Published in Expert review of clinical immunology (01.02.2014)
Published in Expert review of clinical immunology (01.02.2014)
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