Loss and gain of Drosophila TDP-43 impair synaptic efficacy and motor control leading to age-related neurodegeneration by loss-of-function phenotypes
Diaper, Danielle C, Adachi, Yoshitsugu, Sutcliffe, Ben, Humphrey, Dickon M, Elliott, Christopher J H, Stepto, Alan, Ludlow, Zoe N, Vanden Broeck, Lies, Callaerts, Patrick, Dermaut, Bart, Al-Chalabi, Ammar, Shaw, Christopher E, Robinson, Iain M, Hirth, Frank
Published in Human molecular genetics (15.04.2013)
Published in Human molecular genetics (15.04.2013)
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TDP-43 Loss-of-Function Causes Neuronal Loss Due to Defective Steroid Receptor-Mediated Gene Program Switching in Drosophila
Vanden Broeck, Lies, Naval-Sánchez, Marina, Adachi, Yoshitsugu, Diaper, Danielle, Dourlen, Pierre, Chapuis, Julien, Kleinberger, Gernot, Gistelinck, Marc, Van Broeckhoven, Christine, Lambert, Jean-Charles, Hirth, Frank, Aerts, Stein, Callaerts, Patrick, Dermaut, Bart
Published in Cell reports (Cambridge) (31.01.2013)
Published in Cell reports (Cambridge) (31.01.2013)
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Journal Article
TDP-43-mediated neurodegeneration: towards a loss-of-function hypothesis?
Vanden Broeck, Lies, Callaerts, Patrick, Dermaut, Bart
Published in Trends in molecular medicine (01.02.2014)
Published in Trends in molecular medicine (01.02.2014)
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Journal Article
Ancestral regulatory mechanisms specify conserved midbrain circuitry in arthropods and vertebrates
Bridi, Jessika C., Ludlow, Zoe N., Kottler, Benjamin, Hartmann, Beate, Vanden Broeck, Lies, Dearlove, Jonah, Göker, Markus, Strausfeld, Nicholas J., Callaerts, Patrick, Hirth, Frank
Published in Proceedings of the National Academy of Sciences - PNAS (11.08.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (11.08.2020)
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Journal Article
Hearing regulates Drosophila aggression
Versteven, Marijke, Vanden Broeck, Lies, Geurten, Bart, Zwarts, Liesbeth, Decraecker, Lisse, Beelen, Melissa, Göpfert, Martin C., Heinrich, Ralf, Callaerts, Patrick
Published in Proceedings of the National Academy of Sciences - PNAS (21.02.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (21.02.2017)
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The genetic basis of natural variation in mushroom body size in Drosophila melanogaster
Zwarts, Liesbeth, Vanden Broeck, Lies, Cappuyns, Elisa, Ayroles, Julien F., Magwire, Michael M., Vulsteke, Veerle, Clements, Jason, Mackay, Trudy F. C., Callaerts, Patrick
Published in Nature communications (11.12.2015)
Published in Nature communications (11.12.2015)
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Functional complementation in Drosophila to predict the pathogenicity of TARDBP variants: evidence for a loss-of-function mechanism
Vanden Broeck, Lies, Kleinberger, Gernot, Chapuis, Julien, Gistelinck, Marc, Amouyel, Philippe, Van Broeckhoven, Christine, Lambert, Jean-Charles, Callaerts, Patrick, Dermaut, Bart
Published in Neurobiology of aging (01.02.2015)
Published in Neurobiology of aging (01.02.2015)
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Developmental Expression of 4-Repeat-Tau Induces Neuronal Aneuploidy in Drosophila Tauopathy Models
Malmanche, Nicolas, Dourlen, Pierre, Gistelinck, Marc, Demiautte, Florie, Link, Nichole, Dupont, Cloé, Vanden Broeck, Lies, Werkmeister, Elisabeth, Amouyel, Philippe, Bongiovanni, Antonino, Bauderlique, Hélène, Moechars, Dieder, Royou, Anne, Bellen, Hugo J., Lafont, Frank, Callaerts, Patrick, Lambert, Jean-Charles, Dermaut, Bart
Published in Scientific reports (23.01.2017)
Published in Scientific reports (23.01.2017)
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P2‐134: TDP‐43 neurotoxicity is caused by a failure of steroid receptor–dependent transcriptional program switching in Drosophila
Dermaut, Bart, Broeck, Lies Vanden, Sanchez, Marina Naval, Adachi, Yoshitsugu, Diaper, Danielle, Kleinberger, Gernot, Gistelinck, Marc, Van Broeckhoven, Christine, Hirth, Frank, Aerts, Stein, Callaerts, Patrick
Published in Alzheimer's & dementia (01.07.2012)
Published in Alzheimer's & dementia (01.07.2012)
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Journal Article
TDP-43 neurotoxicity is caused by a failure of steroid receptor–dependent transcriptional program switching in Drosophila
Dermaut, Bart, Broeck, Lies Vanden, Sanchez, Marina Naval, Adachi, Yoshitsugu, Diaper, Danielle, Kleinberger, Gernot, Gistelinck, Marc, Van Broeckhoven, Christine, Hirth, Frank, Aerts, Stein, Callaerts, Patrick
Published in Alzheimer's & dementia (01.07.2012)
Published in Alzheimer's & dementia (01.07.2012)
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Journal Article
Ancestral regulatory mechanisms specify conserved midbrain circuitry in arthropods and vertebrates
Bridi, Jessika C, Ludlow, Zoe N, Kottler, Benjamin, Hartmann, Beate, Lies Vanden Broeck, Dearlove, Jonah, Goeker, Markus, Strausfeld, Nicholas J, Callaerts, Patrick, Hirth, Frank
Published in bioRxiv (28.10.2019)
Published in bioRxiv (28.10.2019)
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