How precise is quantitative prediction of pharmacokinetic effects due to drug-drug interactions and genotype from in vitro data? A comprehensive analysis on the example CYP2D6 and CYP2C19 substrates
Dücker, Christof, Brockmöller, Jürgen
Published in Pharmacology & therapeutics (Oxford) (01.01.2021)
Published in Pharmacology & therapeutics (Oxford) (01.01.2021)
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Journal Article
Stereoselectivity in Cell Uptake by SLC22 Organic Cation Transporters 1, 2, and 3
Gebauer, Lukas, Jensen, Ole, Rafehi, Muhammad, Brockmöller, Jürgen
Published in Journal of medicinal chemistry (14.12.2023)
Published in Journal of medicinal chemistry (14.12.2023)
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Journal Article
Confounding effects of caffeine on neuroplasticity induced by transcranial alternating current stimulation and paired associative stimulation
Zulkifly, Mohd Faizal Mohd, Merkohitaj, Ornela, Brockmöller, Jürgen, Paulus, Walter
Published in Clinical neurophysiology (01.06.2021)
Published in Clinical neurophysiology (01.06.2021)
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Journal Article
Increased Systemic Exposure and Stronger Cardiovascular and Metabolic Adverse Reactions to Fenoterol in Individuals with Heritable OCT1 Deficiency
Tzvetkov, Mladen V, Matthaei, Johannes, Pojar, Sherin, Faltraco, Frank, Vogler, Sabrina, Prukop, Thomas, Seitz, Tina, Brockmöller, Jürgen
Published in Clinical pharmacology and therapeutics (01.05.2018)
Published in Clinical pharmacology and therapeutics (01.05.2018)
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Journal Article
Variability and Heritability of Thiamine Pharmacokinetics With Focus on OCT1 Effects on Membrane Transport and Pharmacokinetics in Humans
Jensen, Ole, Matthaei, Johannes, Blome, Felix, Schwab, Matthias, Tzvetkov, Mladen V., Brockmöller, Jürgen
Published in Clinical pharmacology and therapeutics (01.03.2020)
Published in Clinical pharmacology and therapeutics (01.03.2020)
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Journal Article
Targeted mutagenesis of negatively charged amino acids outlining the substrate translocation path within the human organic cation transporter 3
Redeker, Kyra-Elisa M., Schröder, Sophie, Dücker, Christof, Brockmöller, Jürgen, Gebauer, Lukas
Published in Biochemical pharmacology (01.05.2024)
Published in Biochemical pharmacology (01.05.2024)
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Journal Article
Graft-derived cell-free DNA, a noninvasive early rejection and graft damage marker in liver transplantation: A prospective, observational, multicenter cohort study
Schütz, Ekkehard, Fischer, Anna, Beck, Julia, Harden, Markus, Koch, Martina, Wuensch, Tilo, Stockmann, Martin, Nashan, Björn, Kollmar, Otto, Matthaei, Johannes, Kanzow, Philipp, Walson, Philip D, Brockmöller, Jürgen, Oellerich, Michael
Published in PLoS medicine (25.04.2017)
Published in PLoS medicine (25.04.2017)
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Journal Article
Stereoselective cell uptake of adrenergic agonists and antagonists by organic cation transporters
Jensen, Ole, Rafehi, Muhammad, Tzvetkov, Mladen V., Brockmöller, Jürgen
Published in Biochemical pharmacology (01.01.2020)
Published in Biochemical pharmacology (01.01.2020)
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Journal Article
Differences in Metformin and Thiamine Uptake between Human and Mouse Organic Cation Transporter 1: Structural Determinants and Potential Consequences for Intrahepatic Concentrations
Meyer, Marleen J, Tuerkova, Alzbeta, Römer, Sarah, Wenzel, Christoph, Seitz, Tina, Gaedcke, Jochen, Oswald, Stefan, Brockmöller, Jürgen, Zdrazil, Barbara, Tzvetkov, Mladen V
Published in Drug metabolism and disposition (01.12.2020)
Published in Drug metabolism and disposition (01.12.2020)
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Journal Article
Overlap and Specificity in the Substrate Spectra of Human Monoamine Transporters and Organic Cation Transporters 1, 2, and 3
Gebauer, Lukas, Jensen, Ole, Neif, Maria, Brockmöller, Jürgen, Dücker, Christof
Published in International journal of molecular sciences (26.11.2021)
Published in International journal of molecular sciences (26.11.2021)
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Journal Article