Characterisation of CadR from Pseudomonas aeruginosa: a Cd(II)-responsive MerR homologue
Brocklehurst, K.R, Megit, S.J, Morby, A.P
Published in Biochemical and biophysical research communications (22.08.2003)
Published in Biochemical and biophysical research communications (22.08.2003)
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ZntR is a Zn(II)‐responsive MerR‐like transcriptional regulator of zntA in Escherichia coli
Brocklehurst, Kathryn R., Hobman, Jon L., Lawley, Blair, Blank, Lindsay, Marshall, Samantha J., Brown, Nigel L., Morby, Andrew P.
Published in Molecular microbiology (01.02.1999)
Published in Molecular microbiology (01.02.1999)
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Inhibition of lipolysis and lipogenesis in isolated rat adipocytes with AICAR, a cell-permeable activator of AMP-activated protein kinase
Sullivan, Jane E., Brocklehurst, Katy J., Marley, Anna E., Carey, Frank, Carling, David, Beri, Raj K.
Published in FEBS letters (10.10.1994)
Published in FEBS letters (10.10.1994)
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Variation in aspects of cysteine proteinase catalytic mechanism deduced by spectroscopic observation of dithioester intermediates, kinetic analysis and molecular dynamics simulations
Reid, J D, Hussain, S, Sreedharan, S K, Bailey, T S, Pinitglang, S, Thomas, E W, Verma, C S, Brocklehurst, K
Published in Biochemical journal (15.07.2001)
Published in Biochemical journal (15.07.2001)
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Ionization characteristics of the Cys-25/His-159 interactive system and of the modulatory group of papain : resolution of ambiguity by electronic perturbation of the quasi-2-mercaptopyridine leaving group in a new pyrimidyl disulphide reactivity probe
MELLOR, G. W, THOMAS, E. W, TOPHAM, C. M, BROCKLEHURST, K
Published in Biochemical journal (15.02.1993)
Published in Biochemical journal (15.02.1993)
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Polyclonal antibody-catalysed amide hydrolysis
GALLACHER, G, SEARCEY, M, JACKSON, C. S, BROCKLEHURST, K
Published in Biochemical journal (15.06.1992)
Published in Biochemical journal (15.06.1992)
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Molecular basis of the activity of the phytopathogen pectin methylesterase
Fries, M, Ihrig, J, Brocklehurst, K, Shevchik, V.E, Pickersgill, R.W
Published in The EMBO journal (05.09.2007)
Published in The EMBO journal (05.09.2007)
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Clarification of the pH-dependent kinetic behaviour of papain by using reactivity probes and analysis of alkylation and catalysed acylation reactions in terms of multihydronic state models: implications for electrostatics calculations and interpretation of the consequences of site-specific mutations such as Asp-158-Asn and Asp-158-Glu
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Structure-function relationships in the cysteine proteinases actinidin, papain and papaya proteinase Ω : three-dimensional structure of papaya proteinase Ω deduced by knowledge-based modelling and active-centre characteristics determined by two-hydronic-state reactivity probe kinetics and kinetics of catalysis
TOPHAM, C. M, SALIH, E, FRAZAO, C, KOWLESSUR, D, OVERINGTON, J. P, THOMAS, M, BROCKLEHURST, S. M, PATEL, M, THOMAS, E. W, BROCKLEHURST, K
Published in Biochemical journal (15.11.1991)
Published in Biochemical journal (15.11.1991)
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