Pharmacological regulation of insulin secretion in MIN6 cells through the fatty acid receptor GPR40: identification of agonist and antagonist small molecules
Briscoe, Celia P, Peat, Andrew J, McKeown, Stephen C, Corbett, David F, Goetz, Aaron S, Littleton, Thomas R, McCoy, David C, Kenakin, Terry P, Andrews, John L, Ammala, Carina, Fornwald, James A, Ignar, Diane M, Jenkinson, Stephen
Published in British journal of pharmacology (01.07.2006)
Published in British journal of pharmacology (01.07.2006)
Get full text
Journal Article
The Orphan G Protein-coupled Receptor GPR40 Is Activated by Medium and Long Chain Fatty Acids
Briscoe, Celia P, Tadayyon, Mohammad, Andrews, John L, Benson, William G, Chambers, Jon K, Eilert, Michelle M, Ellis, Catherine, Elshourbagy, Nabil A, Goetz, Aaron S, Minnick, Dana T, Murdock, Paul R, Sauls, Jr, Howard R, Shabon, Usman, Spinage, Lisa D, Strum, Jay C, Szekeres, Philip G, Tan, Kong B, Way, James M, Ignar, Diane M, Wilson, Shelagh, Muir, Alison I
Published in The Journal of biological chemistry (28.03.2003)
Published in The Journal of biological chemistry (28.03.2003)
Get full text
Journal Article
Synthesis and activity of small molecule GPR40 agonists
Garrido, Dulce M., Corbett, David F., Dwornik, Kate A., Goetz, Aaron S., Littleton, Thomas R., McKeown, Steve C., Mills, Wendy Y., Smalley, Terrence L., Briscoe, Celia P., Peat, Andrew J.
Published in Bioorganic & medicinal chemistry letters (01.04.2006)
Published in Bioorganic & medicinal chemistry letters (01.04.2006)
Get full text
Journal Article
Solid phase synthesis and SAR of small molecule agonists for the GPR40 receptor
McKeown, Stephen C., Corbett, David F., Goetz, Aaron S., Littleton, Thomas R., Bigham, Eric, Briscoe, Celia P., Peat, Andrew J., Watson, Steve P, Hickey, Deirdre M.B.
Published in Bioorganic & medicinal chemistry letters (15.03.2007)
Published in Bioorganic & medicinal chemistry letters (15.03.2007)
Get full text
Journal Article
Limited role for SREBP-1c in defective glucose-induced insulin secretion from Zucker diabetic fatty rat islets: a functional and gene profiling analysis
Parton, Laura E, McMillen, Patrick J, Shen, Yingnian, Docherty, Elizabeth, Sharpe, Erin, Diraison, Frederique, Briscoe, Celia P, Rutter, Guy A
Published in American journal of physiology: endocrinology and metabolism (01.11.2006)
Published in American journal of physiology: endocrinology and metabolism (01.11.2006)
Get full text
Journal Article
Alteration of the glucagon axis in GPR120 (FFAR4) knockout mice: a role for GPR120 in glucagon secretion
Suckow, Arthur T, Polidori, David, Yan, Wen, Chon, Suhyoun, Ma, Jing Ying, Leonard, James, Briscoe, Celia P
Published in The Journal of biological chemistry (30.05.2014)
Published in The Journal of biological chemistry (30.05.2014)
Get full text
Journal Article
Key Questions for Translation of FFA Receptors: From Pharmacology to Medicines
Get full text
Book Chapter
Journal Article
Effects of Meal Size on the Release of GLP-1 and PYY After Roux-en-Y Gastric Bypass Surgery in Obese Subjects With or Without Type 2 Diabetes
Yan, Wen, Polidori, David, Yieh, Lynn, Di, Jianing, Wu, Xiaodong, Moreno, Veronica, Li, Lina, Briscoe, Celia P., Shankley, Nigel, Dohm, G. Lynis, Pories, Walter J.
Published in Obesity surgery (01.11.2014)
Published in Obesity surgery (01.11.2014)
Get full text
Journal Article
Alteration of the Glucagon Axis in GPR120 (FFAR4) Knockout Mice
Suckow, Arthur T., Polidori, David, Yan, Wen, Chon, Suhyoun, Ma, Jing Ying, Leonard, James, Briscoe, Celia P.
Published in The Journal of biological chemistry (01.05.2014)
Published in The Journal of biological chemistry (01.05.2014)
Get full text
Journal Article
Discovery of 6,7-Dihydro‑5H‑pyrrolo[2,3‑a]pyrimidines as Orally Available G Protein-Coupled Receptor 119 Agonists
Katamreddy, Subba R, Carpenter, Andrew J, Ammala, Carina E, Boros, Eric E, Brashear, Ron L, Briscoe, Celia P, Bullard, Sarah R, Caldwell, Richard D, Conlee, Christopher R, Croom, Dallas K, Hart, Shane M, Heyer, Dennis O, Johnson, Paul R, Kashatus, Jennifer A, Minick, Doug J, Peckham, Gregory E, Ross, Sean A, Roller, Shane G, Samano, Vicente A, Sauls, Howard R, Tadepalli, Sarva M, Thompson, James B, Xu, Yun, Way, James M
Published in Journal of medicinal chemistry (27.12.2012)
Published in Journal of medicinal chemistry (27.12.2012)
Get full text
Journal Article
Over-expression of sterol-regulatory-element-binding protein-1c (SREBP1c) in rat pancreatic islets induces lipogenesis and decreases glucose-stimulated insulin release: modulation by 5-aminoimidazole-4-carboxamide ribonucleoside (AICAR)
Diraison, Frédérique, Parton, Laura, Ferré, Pascal, Foufelle, Fabienne, Briscoe, Celia P, Leclerc, Isabelle, Rutter, Guy A
Published in Biochemical journal (15.03.2004)
Published in Biochemical journal (15.03.2004)
Get full text
Journal Article
Pharmacological characterization of a small molecule inhibitor of c-Jun kinase
Cho, Helen, Black, Shawn C, Looper, David, Shi, Manli, Kelly-Sullivan, Dawn, Timofeevski, Sergei, Siegel, Karen, Yu, Xiao-Hong, McDonnell, Scott R, Chen, Ping, Yie, Junming, Ogilvie, Kathleen M, Fraser, James, Briscoe, Celia P
Published in American journal of physiology: endocrinology and metabolism (01.11.2008)
Published in American journal of physiology: endocrinology and metabolism (01.11.2008)
Get full text
Journal Article
Impact of PPARγ overexpression and activation on pancreatic islet gene expression profile analyzed with oligonucleotide microarrays
Parton, Laura E., Diraison, Frédérique, Neill, Suzanne E., Ghosh, Sujoy K., Rubino, Mark A., Bisi, John E., Briscoe, Celia P., Rutter, Guy A.
Published in American journal of physiology: endocrinology and metabolism (01.09.2004)
Published in American journal of physiology: endocrinology and metabolism (01.09.2004)
Get full text
Journal Article
Discovery of 6,7-Dihydro-5 H -pyrrolo[2,3- a ]pyrimidines as Orally Available G Protein-Coupled Receptor 119 Agonists
Katamreddy, Subba R., Carpenter, Andrew J., Ammala, Carina E., Boros, Eric E., Brashear, Ron L., Briscoe, Celia P., Bullard, Sarah R., Caldwell, Richard D., Conlee, Christopher R., Croom, Dallas K., Hart, Shane M., Heyer, Dennis O., Johnson, Paul R., Kashatus, Jennifer A., Minick, Doug J., Peckham, Gregory E., Ross, Sean A., Roller, Shane G., Samano, Vicente A., Sauls, Howard R., Tadepalli, Sarva M., Thompson, James B., Xu, Yun, Way, James M.
Published in Journal of medicinal chemistry (27.12.2012)
Published in Journal of medicinal chemistry (27.12.2012)
Get full text
Journal Article
Pharmacological characterization of a small molecule inhibitor of c-Jun kinase
CHO, Helen, BLACK, Shawn C, JUNMING YIE, OGILVIE, Kathleen M, FRASER, James, BRISCOE, Celia P, LOOPER, David, MANLI SHI, KELLY-SULLIVAN, Dawn, TIMOFEEVSKI, Sergei, SIEGEL, Karen, YU, Xiao-Hong, MCDONNELL, Scott R, PING CHEN
Published in American journal of physiology: endocrinology and metabolism (2008)
Get full text
Published in American journal of physiology: endocrinology and metabolism (2008)
Journal Article
LEPTIN RECEPTOR LONG-FORM SIGNALLING IN A HUMAN LIVER CELL LINE
Briscoe, Celia P., Hanif, Shahid, Arch, Jonathan R.S., Tadayyon, Mohammad
Published in Cytokine (Philadelphia, Pa.) (21.05.2001)
Published in Cytokine (Philadelphia, Pa.) (21.05.2001)
Get full text
Journal Article
Impact of PPARgamma overexpression and activation on pancreatic islet gene expression profile analyzed with oligonucleotide microarrays
Parton, Laura E, Diraison, Frédérique, Neill, Suzanne E, Ghosh, Sujoy K, Rubino, Mark A, Bisi, John E, Briscoe, Celia P, Rutter, Guy A
Published in American journal of physiology: endocrinology and metabolism (01.09.2004)
Get full text
Published in American journal of physiology: endocrinology and metabolism (01.09.2004)
Journal Article
Impact of PPARγ overexpression and activation on pancreatic islet gene expression profile analyzed with oligonucleotide microarrays
PARTON, Laura E, DIRAISON, Frédérique, NEILL, Suzanne E, GHOSH, Sujoy K, RUBINO, Mark A, BISI, John E, BRISCOE, Celia P, RUTTER, Guy A
Published in American journal of physiology: endocrinology and metabolism (2004)
Get full text
Published in American journal of physiology: endocrinology and metabolism (2004)
Journal Article