Rab27a co-ordinates actin-dependent transport by controlling organelle-associated motors and track assembly proteins
Alzahofi, Noura, Welz, Tobias, Robinson, Christopher L., Page, Emma L., Briggs, Deborah A., Stainthorp, Amy K., Reekes, James, Elbe, David A., Straub, Felix, Kallemeijn, Wouter W., Tate, Edward W., Goff, Philip S., Sviderskaya, Elena V., Cantero, Marta, Montoliu, Lluis, Nedelec, Francois, Miles, Amanda K., Bailly, Maryse, Kerkhoff, Eugen, Hume, Alistair N.
Published in Nature communications (13.07.2020)
Published in Nature communications (13.07.2020)
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Myosin-Va and Dynamic Actin Oppose Microtubules to Drive Long-Range Organelle Transport
Evans, Richard D., Robinson, Christopher, Briggs, Deborah A., Tooth, David J., Ramalho, Jose S., Cantero, Marta, Montoliu, Lluis, Patel, Shyamal, Sviderskaya, Elena V., Hume, Alistair N.
Published in Current biology (04.08.2014)
Published in Current biology (04.08.2014)
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The adaptor protein melanophilin regulates dynamic myosin-Va:cargo interaction and dendrite development in melanocytes
Robinson, Christopher L, Evans, Richard D, Sivarasa, Kajana, Ramalho, Jose S, Briggs, Deborah A, Hume, Alistair N
Published in Molecular biology of the cell (15.03.2019)
Published in Molecular biology of the cell (15.03.2019)
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Nucleotide exchange factor Rab3GEP requires DENN and non-DENN elements for activation and targeting of Rab27a
Sanzà, Paolo, Evans, Richard D, Briggs, Deborah A, Cantero, Marta, Montoliu, Lluis, Patel, Shyamal, Sviderskaya, Elena V, Itzen, Aymelt, Figueiredo, Ana C, Seabra, Miguel C, Hume, Alistair N
Published in Journal of cell science (30.04.2019)
Published in Journal of cell science (30.04.2019)
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Actomyosin organelle functions of SPIRE actin nucleators precede animal evolution
Kollmar, Martin, Welz, Tobias, Ravi, Aishwarya, Kaufmann, Thomas, Alzahofi, Noura, Hatje, Klas, Alghamdi, Asmahan, Kim, Jiyu, Briggs, Deborah A., Samol-Wolf, Annette, Pylypenko, Olena, Hume, Alistair N., Burkhardt, Pawel, Faix, Jan, Kerkhoff, Eugen
Published in Communications biology (08.07.2024)
Published in Communications biology (08.07.2024)
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Residues contributing to drug transport by ABCG2 are localised to multiple drug-binding pockets
Cox, Megan H, Kapoor, Parth, Briggs, Deborah A, Kerr, Ian D
Published in Biochemical journal (15.05.2018)
Published in Biochemical journal (15.05.2018)
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Journal Article
Vinca alkaloid binding to P-glycoprotein occurs in a processive manner
Iqbal, Shagufta, Flux, Caitlin, Briggs, Deborah A., Deplazes, Evelyne, Long, Jiansi, Skrzypek, Ruth, Rothnie, Alice, Kerr, Ian D., Callaghan, Richard
Published in Biochimica et biophysica acta. Biomembranes (01.10.2022)
Published in Biochimica et biophysica acta. Biomembranes (01.10.2022)
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Application of fluorescence correlation spectroscopy to study substrate binding in styrene maleic acid lipid copolymer encapsulated ABCG2
Horsey, Aaron J., Briggs, Deborah A., Holliday, Nicholas D., Briddon, Stephen J., Kerr, Ian D.
Published in Biochimica et biophysica acta. Biomembranes (01.06.2020)
Published in Biochimica et biophysica acta. Biomembranes (01.06.2020)
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A time-resolved Förster resonance energy transfer assay to investigate drug and inhibitor binding to ABCG2
Mitchell-White, James I., Briggs, Deborah A., Mistry, Sarah J., Mbiwan, Hannah A., Kellam, Barrie, Holliday, Nicholas D., Briddon, Stephen J., Kerr, Ian D.
Published in Archives of biochemistry and biophysics (01.03.2024)
Published in Archives of biochemistry and biophysics (01.03.2024)
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Cross-linking, DEER-spectroscopy and molecular dynamics confirm the inward facing state of P-glycoprotein in a lipid membrane
Carey Hulyer, Alex R., Briggs, Deborah A., O'Mara, Megan L., Kerr, Ian D., Harmer, Jeffrey R., Callaghan, Richard
Published in Journal of structural biology (01.07.2020)
Published in Journal of structural biology (01.07.2020)
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Novel RAB27A Variant Associated with Late-Onset Hemophagocytic Lymphohistiocytosis Alters Effector Protein Binding
Zondag, Timo C. E., Torralba-Raga, Lamberto, Van Laar, Jan A. M., Hermans, Maud A. W., Bouman, Arjen, Hollink, Iris H. I. M., Van Hagen, P. Martin, Briggs, Deborah A., Hume, Alistair N., Bryceson, Yenan T.
Published in Journal of clinical immunology (01.11.2022)
Published in Journal of clinical immunology (01.11.2022)
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Animal evolution coincides with a novel degree of freedom in exocytic transport processes
Kollmar, Martin, Welz, Tobias, Straub, Felix, Alzahofi, Noura, Hatje, Klas, Briggs, Deborah A, Samol-Wolf, Annette, Burkhardt, Pawel, Hume, Alistair, Kerkhoff, Eugen
Published in bioRxiv (28.03.2019)
Published in bioRxiv (28.03.2019)
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Paper
Rab27a co-ordinates actin-dependent transport by controlling organelle-associated motors and track assembly proteins
Alzahofi, Noura, Robinson, Christopher L, Welz, Tobias, Page, Emma L, Briggs, Deborah A, Stainthorp, Amy K, Reekes, James, Elbe, David A, Straub, Felix, Tate, Edward W, Goff, Philip S, Sviderskaya, Elena V, Cantero, Marta, Montoliu, Lluis, Bailly, Maryse, Kerkhoff, Eugen, Hume, Alistair N
Published in bioRxiv (03.05.2018)
Published in bioRxiv (03.05.2018)
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