Prion-like low complexity regions enable avid virus-host interactions during HIV-1 infection
Wei, Guochao, Iqbal, Naseer, Courouble, Valentine V, Francis, Ashwanth C, Singh, Parmit K, Hudait, Arpa, Annamalai, Arun S, Bester, Stephanie, Huang, Szu-Wei, Shkriabai, Nikoloz, Briganti, Lorenzo, Haney, Reed, KewalRamani, Vineet N, Voth, Gregory A, Engelman, Alan N, Melikyan, Gregory B, Griffin, Patrick R, Asturias, Francisco, Kvaratskhelia, Mamuka
Published in Nature communications (06.10.2022)
Published in Nature communications (06.10.2022)
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Journal Article
Structural and Mechanistic Bases of Viral Resistance to HIV-1 Capsid Inhibitor Lenacapavir
Bester, Stephanie M, Adu-Ampratwum, Daniel, Annamalai, Arun S, Wei, Guochao, Briganti, Lorenzo, Murphy, Bridget C, Haney, Reed, Fuchs, James R, Kvaratskhelia, Mamuka
Published in mBio (26.10.2022)
Published in mBio (26.10.2022)
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Journal Article
The Drug-Induced Interface That Drives HIV-1 Integrase Hypermultimerization and Loss of Function
Singer, Matthew R, Dinh, Tung, Levintov, Lev, Annamalai, Arun S, Rey, Juan S, Briganti, Lorenzo, Cook, Nicola J, Pye, Valerie E, Taylor, Ian A, Kim, Kyungjin, Engelman, Alan N, Kim, Baek, Perilla, Juan R, Kvaratskhelia, Mamuka, Cherepanov, Peter
Published in mBio (28.02.2023)
Published in mBio (28.02.2023)
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Low-resolution molecular shape, biochemical characterization and emulsification properties of a halotolerant esterase from Bacillus licheniformis
Leite, Ana Elisa T., Briganti, Lorenzo, de Araújo, Evandro Ares, Pellegrini, Vanessa de Oliveira Arnoldi, Camilo, Cesar Moyses, Polikarpov, Igor
Published in European biophysics journal (01.09.2020)
Published in European biophysics journal (01.09.2020)
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Structural and molecular dynamics investigations of ligand stabilization via secondary binding site interactions in Paenibacillus xylanivorans GH11 xylanase
Briganti, Lorenzo, Capetti, Caio, Pellegrini, Vanessa O.A., Ghio, Silvina, Campos, Eleonora, Nascimento, Alessandro S., Polikarpov, Igor
Published in Computational and structural biotechnology journal (01.01.2021)
Published in Computational and structural biotechnology journal (01.01.2021)
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Transformation of xylan into value-added biocommodities using Thermobacillus composti GH10 xylanase
Sepulchro, Ana Gabriela Veiga, Pellegrini, Vanessa O.A., Briganti, Lorenzo, de Araujo, Evandro A., de Araujo, Simara S., Polikarpov, Igor
Published in Carbohydrate polymers (01.11.2020)
Published in Carbohydrate polymers (01.11.2020)
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Unravelling biochemical and structural features of Bacillus licheniformis GH5 mannanase using site-directed mutagenesis and high-resolution protein crystallography studies
Briganti, Lorenzo, Manzine, Livia R., de Mello Capetti, Caio Cesar, de Araújo, Evandro Ares, de Oliveira Arnoldi Pellegrini, Vanessa, Guimaraes, Francisco Eduardo Gontijo, de Oliveira Neto, Mario, Polikarpov, Igor
Published in International journal of biological macromolecules (01.08.2024)
Published in International journal of biological macromolecules (01.08.2024)
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Unlocking the structural features for the xylobiohydrolase activity of an unusual GH11 member identified in a compost‐derived consortium
Kadowaki, Marco A. S., Briganti, Lorenzo, Evangelista, Danilo E., Echevarría‐Poza, Alberto, Tryfona, Theodora, Pellegrini, Vanessa O. A., Nakayama, Darlan G., Dupree, Paul, Polikarpov, Igor
Published in Biotechnology and bioengineering (01.10.2021)
Published in Biotechnology and bioengineering (01.10.2021)
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Mechanisms of HIV-1 integrase resistance to dolutegravir and potent inhibition of drug-resistant variants
Li, Min, Oliveira Passos, Dario, Shan, Zelin, Smith, Steven J, Sun, Qinfang, Biswas, Avik, Choudhuri, Indrani, Strutzenberg, Timothy S, Haldane, Allan, Deng, Nanjie, Li, Zhaoyang, Zhao, Xue Zhi, Briganti, Lorenzo, Kvaratskhelia, Mamuka, Burke, Jr, Terrence R, Levy, Ronald M, Hughes, Stephen H, Craigie, Robert, Lyumkis, Dmitry
Published in Science advances (21.07.2023)
Published in Science advances (21.07.2023)
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The structural and mechanistic bases for the viral resistance to allosteric HIV-1 integrase inhibitor pirmitegravir
Dinh, Tung, Tber, Zahira, Rey, Juan S, Mengshetti, Seema, Annamalai, Arun S, Haney, Reed, Briganti, Lorenzo, Amblard, Franck, Fuchs, James R, Cherepanov, Peter, Kim, Kyungjin, Schinazi, Raymond F, Perilla, Juan R, Kim, Baek, Kvaratskhelia, Mamuka
Published in bioRxiv (26.01.2024)
Published in bioRxiv (26.01.2024)
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