Effects of metformin and other biguanides on oxidative phosphorylation in mitochondria
Bridges, Hannah R, Jones, Andrew J Y, Pollak, Michael N, Hirst, Judy
Published in Biochemical journal (15.09.2014)
Published in Biochemical journal (15.09.2014)
Get more information
Journal Article
Cryo-EM structures of complex I from mouse heart mitochondria in two biochemically defined states
Agip, Ahmed-Noor A, Blaza, James N, Bridges, Hannah R, Viscomi, Carlo, Rawson, Shaun, Muench, Stephen P, Hirst, Judy
Published in Nature structural & molecular biology (01.07.2018)
Published in Nature structural & molecular biology (01.07.2018)
Get full text
Journal Article
Cryo-EM structures define ubiquinone-10 binding to mitochondrial complex I and conformational transitions accompanying Q-site occupancy
Chung, Injae, Wright, John J, Bridges, Hannah R, Ivanov, Bozhidar S, Biner, Olivier, Pereira, Caroline S, Arantes, Guilherme M, Hirst, Judy
Published in Nature communications (19.05.2022)
Published in Nature communications (19.05.2022)
Get full text
Journal Article
Complexome profile of Toxoplasma gondii mitochondria identifies divergent subunits of respiratory chain complexes including new subunits of cytochrome bc1 complex
Maclean, Andrew E, Bridges, Hannah R, Silva, Mariana F, Ding, Shujing, Ovciarikova, Jana, Hirst, Judy, Sheiner, Lilach
Published in PLoS pathogens (01.03.2021)
Published in PLoS pathogens (01.03.2021)
Get full text
Journal Article
Structure of inhibitor-bound mammalian complex I
Bridges, Hannah R, Fedor, Justin G, Blaza, James N, Di Luca, Andrea, Jussupow, Alexander, Jarman, Owen D, Wright, John J, Agip, Ahmed-Noor A, Gamiz-Hernandez, Ana P, Roessler, Maxie M, Kaila, Ville R I, Hirst, Judy
Published in Nature communications (16.10.2020)
Published in Nature communications (16.10.2020)
Get full text
Journal Article
Structural basis for a complex I mutation that blocks pathological ROS production
Yin, Zhan, Burger, Nils, Kula-Alwar, Duvaraka, Aksentijević, Dunja, Bridges, Hannah R, Prag, Hiran A, Grba, Daniel N, Viscomi, Carlo, James, Andrew M, Mottahedin, Amin, Krieg, Thomas, Murphy, Michael P, Hirst, Judy
Published in Nature communications (29.01.2021)
Published in Nature communications (29.01.2021)
Get full text
Journal Article
Subunit NDUFV3 is present in two distinct isoforms in mammalian complex I
Bridges, Hannah R., Mohammed, Khairunnisa, Harbour, Michael E., Hirst, Judy
Published in Biochimica et biophysica acta (01.03.2017)
Published in Biochimica et biophysica acta (01.03.2017)
Get full text
Journal Article
Cryo-electron microscopy reveals how acetogenins inhibit mitochondrial respiratory complex I
Grba, Daniel N., Blaza, James N., Bridges, Hannah R., Agip, Ahmed-Noor A., Yin, Zhan, Murai, Masatoshi, Miyoshi, Hideto, Hirst, Judy
Published in The Journal of biological chemistry (01.03.2022)
Published in The Journal of biological chemistry (01.03.2022)
Get full text
Journal Article
The mechanism of catalysis by type-II NADH:quinone oxidoreductases
Blaza, James N, Bridges, Hannah R, Aragão, David, Dunn, Elyse A, Heikal, Adam, Cook, Gregory M, Nakatani, Yoshio, Hirst, Judy
Published in Scientific reports (09.01.2017)
Published in Scientific reports (09.01.2017)
Get full text
Journal Article
Using Hyperfine Electron Paramagnetic Resonance Spectroscopy to Define the Proton-Coupled Electron Transfer Reaction at Fe–S Cluster N2 in Respiratory Complex I
Le Breton, Nolwenn, Wright, John J, Jones, Andrew J. Y, Salvadori, Enrico, Bridges, Hannah R, Hirst, Judy, Roessler, Maxie M
Published in Journal of the American Chemical Society (15.11.2017)
Published in Journal of the American Chemical Society (15.11.2017)
Get full text
Journal Article
Complexome profile of Toxoplasma gondii mitochondria identifies divergent subunits of respiratory chain complexes including new subunits of cytochrome bc 1 complex
Maclean, Andrew E, Bridges, Hannah R, Silva, Mariana F, Ding, Shujing, Ovciarikova, Jana, Hirst, Judy, Sheiner, Lilach
Published in PLoS pathogens (01.03.2021)
Published in PLoS pathogens (01.03.2021)
Get full text
Journal Article
Structure of the NDH-2 – HQNO inhibited complex provides molecular insight into quinone-binding site inhibitors
Petri, Jessica, Shimaki, Yosuke, Jiao, Wanting, Bridges, Hannah R., Russell, Euan R., Parker, Emily J., Aragão, David, Cook, Gregory M., Nakatani, Yoshio
Published in Biochimica et biophysica acta (01.07.2018)
Published in Biochimica et biophysica acta (01.07.2018)
Get full text
Journal Article
A Self-Assembled Respiratory Chain that Catalyzes NADH Oxidation by Ubiquinone-10 Cycling between Complex I and the Alternative Oxidase
Jones, Andrew J. Y., Blaza, James N., Bridges, Hannah R., May, Benjamin, Moore, Anthony L., Hirst, Judy
Published in Angewandte Chemie (International ed.) (11.01.2016)
Published in Angewandte Chemie (International ed.) (11.01.2016)
Get full text
Journal Article