Reengineering the specificity of the highly selective Clostridium botulinum protease via directed evolution
Dyer, Rebekah P., Isoda, Hariny M., Salcedo, Gabriela S., Speciale, Gaetano, Fletcher, Madison H., Le, Linh Q., Liu, Yi, Brami-Cherrier, Karen, Malik, Shiazah Z., Vazquez-Cintron, Edwin J., Chu, Andrew C., Rupp, David C., Jacky, Birgitte P. S., Nguyen, Thu T. M., Katz, Benjamin B., Steward, Lance E., Majumdar, Sudipta, Brideau-Andersen, Amy D., Weiss, Gregory A.
Published in Scientific reports (15.06.2022)
Published in Scientific reports (15.06.2022)
Get full text
Journal Article
OnabotulinumtoxinA affects cortical recovery period but not occurrence or propagation of cortical spreading depression in rats with compromised blood-brain barrier
Melo-Carrillo, Agustin, Strassman, Andrew M, Schain, Aaron J, Broide, Ron S, Cai, Brian B, Rhéaume, Catherine, Brideau-Andersen, Amy D, Ashina, Sait, Flores-Montanez, Yadira, Brin, Mitchell F, Burstein, Rami
Published in Pain (Amsterdam) (01.09.2021)
Published in Pain (Amsterdam) (01.09.2021)
Get full text
Journal Article
Directed evolution of gene-shuffled IFN-α molecules with activity profiles tailored for treatment of chronic viral diseases
Brideau-Andersen, Amy D, Huang, Xiaojian, Sun, Siu-Chi Chang, Chen, Teddy T, Stark, Diane, Sas, Ian J, Zadik, Linda, Dawes, Glenn N, Guptill, Douglas R, McCord, Robert, Govindarajan, Sridhar, Roy, Ajoy, Yang, Shumin, Gao, Judy, Chen, Yong Hong, Skartved, Niels Jørgen Ø, Pedersen, Annette K, Lin, David, Locher, Christopher P, Rebbapragada, Indrani, Jensen, Anne Dam, Bass, Steven H, Nissen, Torben L. Straight, Viswanathan, Sridhar, Foster, Graham R, Symons, Julian A, Patten, Phillip A
Published in Proceedings of the National Academy of Sciences - PNAS (15.05.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (15.05.2007)
Get full text
Journal Article
A Preclinical Study Comparing the Activity and Potency of OnabotulinumtoxinA and PrabotulinumtoxinA
Rupp, David C, Canty, David, Rhéaume, Catherine, Sondergaard, Birgitte, Niño, Celina, Broide, Ron S, Brideau-Andersen, Amy D
Published in Clinical, cosmetic and investigational dermatology (01.01.2023)
Published in Clinical, cosmetic and investigational dermatology (01.01.2023)
Get full text
Journal Article
OnabotulinumtoxinA exhibits greater efficacy compared to purified botulinum neurotoxin type A (BoNT/A-150 kDa) in peripheral pain models
Subramaniam, Sudhakar R., Nicholson, Greg, Cai, Brian B., Brideau-Andersen, Amy D., Broide, Ron S.
Published in Toxicon (Oxford) (01.01.2021)
Published in Toxicon (Oxford) (01.01.2021)
Get full text
Journal Article
Botulinum Neurotoxin Accelerates the Resolution of Bacterial Skin Infections in Mice
Deng, Liwen, Choi, Samantha, Pinho-Ribeiro, Felipe A., Blake, Kimbria J., Subramaniam, Sudhakar, Baral, Pankaj, Held, Katherine S., Vazquez-Cintron, Edwin, Broide, Ron S., Brideau-Andersen, Amy D., Chiu, Isaac M.
Published in Toxicon (Oxford) (01.07.2022)
Published in Toxicon (Oxford) (01.07.2022)
Get full text
Journal Article
Engineering SNAP23 specificity into the highly selective Clostridium botulinum protease
Dyer, Rebekah P., Isoda, Hariny M., Salcedo, Gabriela S., Speciale, Gaetano, Fletcher, Madison H., Le, Linh Q., Liu, Yi, Malik, Shiazah Z., Vazquez-Cintron, Edwin J., Chu, Andrew C., Rupp, David C., Jacky, Birgitte P.S., Nguyen, Thu T.M., Steward, Lance E., Majumdar, Sudipta, Brideau-Andersen, Amy D., Weiss, Gregory A.
Published in Toxicon (Oxford) (01.01.2021)
Published in Toxicon (Oxford) (01.01.2021)
Get full text
Journal Article
Botulinum Neurotoxin Proteins and Methods to Engineer and Generate Same
Weiss, Gregory A, Brideau-Andersen, Amy D, Dyer, Rebekah P, Rupp, David C, Jacky, Birgitte P.S, Le, Linh Q, Steward, Lance E, Majumdar, Sudipta, Speciale, Gaetano, Fletcher, Madison H
Year of Publication 19.10.2023
Get full text
Year of Publication 19.10.2023
Patent
BOTULINUM NEUROTOXIN PROTEINS AND METHODS TO ENGINEER AND GENERATE SAME
RUPP, David, C, JACKY, Birgitte, P., S, MAJUMDAR, Sudipta, SPECIALE, Gaetano, DYER, Rebekah, P, STEWARD, Lance, E, BRIDEAU-ANDERSEN, Amy, D, WEISS, Gregory, A, FLETCHER, Madison, H, LE, Linh, Q
Year of Publication 05.07.2023
Get full text
Year of Publication 05.07.2023
Patent
Reengineering the Specificity of the Highly Selective Clostridium botulinum Protease via Directed Evolution
Dyer, Rebekah P, Isoda, Hariny M, Salcedo, Gabriela S, Speciale, Gaetano, Fletcher, Madison H, Le, Linh Q, Liu, Yi, Malik, Shiazah Z, Vazquez-Cintron, Edwin J, Chu, Andrew C, Rupp, David C, Jacky, Birgitte Ps, Nguyen, Thu Tm, Steward, Lance E, Majumdar, Sudipta, Brideau-Andersen, Amy D, Weiss, Gregory A
Published in bioRxiv (30.09.2020)
Published in bioRxiv (30.09.2020)
Get full text
Paper