Transcriptomic profiling of pancreatic alpha, beta and delta cell populations identifies delta cells as a principal target for ghrelin in mouse islets
Adriaenssens, Alice E., Svendsen, Berit, Lam, Brian Y. H., Yeo, Giles S. H., Holst, Jens J., Reimann, Frank, Gribble, Fiona M.
Published in Diabetologia (01.10.2016)
Published in Diabetologia (01.10.2016)
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Journal Article
Loss-of-function mutations in the melanocortin 4 receptor in a UK birth cohort
Wade, Kaitlin H, Lam, Brian Y H, Melvin, Audrey, Pan, Warren, Corbin, Laura J, Hughes, David A, Rainbow, Kara, Chen, Jian-Hua, Duckett, Katie, Liu, Xiaoming, Mokrosiński, Jacek, Mörseburg, Alexander, Neaves, Sam, Williamson, Alice, Zhang, Chen, Farooqi, I Sadaf, Yeo, Giles S H, Timpson, Nicholas J, O'Rahilly, Stephen
Published in Nature medicine (01.06.2021)
Published in Nature medicine (01.06.2021)
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Journal Article
Inhibition of mitochondrial function by metformin increases glucose uptake, glycolysis and GDF-15 release from intestinal cells
Yang, Ming, Darwish, Tamana, Larraufie, Pierre, Rimmington, Debra, Cimino, Irene, Goldspink, Deborah A, Jenkins, Benjamin, Koulman, Albert, Brighton, Cheryl A, Ma, Marcella, Lam, Brian Y H, Coll, Anthony P, O'Rahilly, Stephen, Reimann, Frank, Gribble, Fiona M
Published in Scientific reports (28.01.2021)
Published in Scientific reports (28.01.2021)
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Journal Article
Hypothalamic loss of Snord116 recapitulates the hyperphagia of Prader-Willi syndrome
Polex-Wolf, Joseph, Lam, Brian Yh, Larder, Rachel, Tadross, John, Rimmington, Debra, Bosch, Fàtima, Cenzano, Verónica Jiménez, Ayuso, Eduard, Ma, Marcella Kl, Rainbow, Kara, Coll, Anthony P, O'Rahilly, Stephen, Yeo, Giles Sh
Published in The Journal of clinical investigation (01.03.2018)
Published in The Journal of clinical investigation (01.03.2018)
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Journal Article
Microarray, qPCR, and KCNJ5 Sequencing of Aldosterone-Producing Adenomas Reveal Differences in Genotype and Phenotype between Zona Glomerulosa- and Zona Fasciculata-Like Tumors
Azizan, Elena A. B, Lam, Brian Y. H, Newhouse, Stephen J, Zhou, Junhua, Kuc, Rhoda E, Clarke, Jennifer, Happerfield, Lisa, Marker, Alison, Hoffman, Gary J, Brown, Morris J
Published in The journal of clinical endocrinology and metabolism (01.05.2012)
Published in The journal of clinical endocrinology and metabolism (01.05.2012)
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Journal Article
Human embryonic genome activation initiates at the one-cell stage
Asami, Maki, Lam, Brian Y.H., Ma, Marcella K., Rainbow, Kara, Braun, Stefanie, VerMilyea, Matthew D., Yeo, Giles S.H., Perry, Anthony C.F.
Published in Cell stem cell (03.02.2022)
Published in Cell stem cell (03.02.2022)
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Journal Article
Transcriptome analysis of embryonic and adult sensory axons reveals changes in mRNA repertoire localization
Gumy, Laura F, Yeo, Giles S H, Tung, Yi-Chun Loraine, Zivraj, Krishna H, Willis, Dianna, Coppola, Giovanni, Lam, Brian Y H, Twiss, Jeffery L, Holt, Christine E, Fawcett, James W
Published in RNA (Cambridge) (01.01.2011)
Published in RNA (Cambridge) (01.01.2011)
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Journal Article
Marginal zone B cells control the response of follicular helper T cells to a high-cholesterol diet
Nus, Meritxell, Sage, Andrew P, Lu, Yuning, Masters, Leanne, Lam, Brian Y H, Newland, Stephen, Weller, Sandra, Tsiantoulas, Dimitrios, Raffort, Juliette, Marcus, Damiënne, Finigan, Alison, Kitt, Lauren, Figg, Nichola, Schirmbeck, Reinhold, Kneilling, Manfred, Yeo, Giles S H, Binder, Christoph J, de la Pompa, José Luis, Mallat, Ziad
Published in Nature medicine (01.05.2017)
Published in Nature medicine (01.05.2017)
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Journal Article
High Coexpression of the Ghrelin and LEAP2 Receptor GHSR With Pancreatic Polypeptide in Mouse and Human Islets
Gupta, Deepali, Dowsett, Georgina K C, Mani, Bharath K, Shankar, Kripa, Osborne-Lawrence, Sherri, Metzger, Nathan P, Lam, Brian Y H, Yeo, Giles S H, Zigman, Jeffrey M
Published in Endocrinology (Philadelphia) (01.10.2021)
Published in Endocrinology (Philadelphia) (01.10.2021)
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Journal Article
Heterogeneity of hypothalamic pro-opiomelanocortin-expressing neurons revealed by single-cell RNA sequencing
Lam, Brian Y.H, Cimino, Irene, Polex-Wolf, Joseph, Nicole Kohnke, Sara, Rimmington, Debra, Iyemere, Valentine, Heeley, Nicholas, Cossetti, Chiara, Schulte, Reiner, Saraiva, Luis R, Logan, Darren W, Blouet, Clemence, O'Rahilly, Stephen, Coll, Anthony P, Yeo, Giles S.H
Published in Molecular metabolism (Germany) (01.05.2017)
Published in Molecular metabolism (Germany) (01.05.2017)
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Journal Article
Impaired Autophagy in CD11b+ Dendritic Cells Expands CD4+ Regulatory T Cells and Limits Atherosclerosis in Mice
Clement, Marc, Raffort, Juliette, Lareyre, Fabien, Tsiantoulas, Dimitrios, Newland, Stephen, Lu, Yuning, Masters, Leanne, Harrison, James, Saveljeva, Svetlana, Ma, Marcella K.L, Ozsvar-Kozma, Maria, Lam, Brian Y.H, Yeo, Giles S.H, Binder, Christoph J, Kaser, Arthur, Mallat, Ziad
Published in Circulation research (08.11.2019)
Published in Circulation research (08.11.2019)
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Journal Article
Mesenchyme-derived IGF2 is a major paracrine regulator of pancreatic growth and function
Hammerle, Constanze M, Sandovici, Ionel, Brierley, Gemma V, Smith, Nicola M, Zimmer, Warren E, Zvetkova, Ilona, Prosser, Haydn M, Sekita, Yoichi, Lam, Brian Y H, Ma, Marcella, Cooper, Wendy N, Vidal-Puig, Antonio, Ozanne, Susan E, Medina-Gómez, Gema, Constância, Miguel
Published in PLoS genetics (15.10.2020)
Published in PLoS genetics (15.10.2020)
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Journal Article
MCH Regulates SIRT1/FoxO1 and Reduces POMC Neuronal Activity to Induce Hyperphagia, Adiposity, and Glucose Intolerance
Al-Massadi, Omar, Quiñones, Mar, Clasadonte, Jerome, Hernandez-Bautista, René, Romero-Picó, Amparo, Folgueira, Cintia, Morgan, Donald A, Kalló, Imre, Heras, Violeta, Senra, Ana, Funderburk, Samuel C, Krashes, Michael J, Souto, Yara, Fidalgo, Miguel, Luquet, Serge, Chee, Melissa J, Imbernon, Monica, Beiroa, Daniel, García-Caballero, Lucía, Gallego, Rosalia, Lam, Brian Y H, Yeo, Giles, Lopez, Miguel, Liposits, Zsolt, Rahmouni, Kamal, Prevot, Vincent, Dieguez, Carlos, Nogueiras, Ruben
Published in Diabetes (New York, N.Y.) (01.12.2019)
Published in Diabetes (New York, N.Y.) (01.12.2019)
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Journal Article
The initiation of mammalian embryonic transcription: to begin at the beginning
Perry, Anthony C.F., Asami, Maki, Lam, Brian Y.H., Yeo, Giles S.H.
Published in Trends in cell biology (01.05.2023)
Published in Trends in cell biology (01.05.2023)
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Journal Article
The imprinted Igf2-Igf2r axis is critical for matching placental microvasculature expansion to fetal growth
Sandovici, Ionel, Georgopoulou, Aikaterini, Pérez-García, Vicente, Hufnagel, Antonia, López-Tello, Jorge, Lam, Brian Y.H., Schiefer, Samira N., Gaudreau, Chelsea, Santos, Fátima, Hoelle, Katharina, Yeo, Giles S.H., Burling, Keith, Reiterer, Moritz, Fowden, Abigail L., Burton, Graham J., Branco, Cristina M., Sferruzzi-Perri, Amanda N., Constância, Miguel
Published in Developmental cell (10.01.2022)
Published in Developmental cell (10.01.2022)
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Journal Article
Neurochemical Characterization of Brainstem Pro-Opiomelanocortin Cells
Georgescu, Teodora, Lyons, David, Doslikova, Barbora, Garcia, Ana Paula, Marston, Oliver, Burke, Luke K, Chianese, Raffaella, Lam, Brian Y H, Yeo, Giles S H, Rochford, Justin J, Garfield, Alastair S, Heisler, Lora K
Published in Endocrinology (Philadelphia) (01.04.2020)
Published in Endocrinology (Philadelphia) (01.04.2020)
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Journal Article
Topographic mapping of the glioblastoma proteome reveals a triple-axis model of intra-tumoral heterogeneity
Lam, K H Brian, Leon, Alberto J, Hui, Weili, Lee, Sandy Che-Eun, Batruch, Ihor, Faust, Kevin, Klekner, Almos, Hutóczki, Gábor, Koritzinsky, Marianne, Richer, Maxime, Djuric, Ugljesa, Diamandis, Phedias
Published in Nature communications (10.01.2022)
Published in Nature communications (10.01.2022)
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Journal Article
Nonalcoholic fatty liver disease in lean individuals in the United States
Younossi, Zobair M, Stepanova, Maria, Negro, Francesco, Hallaji, Shareh, Younossi, Youssef, Lam, Brian, Srishord, Manirath
Published in Medicine (Baltimore) (01.11.2012)
Published in Medicine (Baltimore) (01.11.2012)
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Journal Article
Dax1 modulates ERα-dependent hypothalamic estrogen sensing in female mice
Ramos-Pittol, Jose M, Fernandes-Freitas, Isabel, Milona, Alexandra, Manchishi, Stephen M, Rainbow, Kara, Lam, Brian Y H, Tadross, John A, Beucher, Anthony, Colledge, William H, Cebola, Inês, Murphy, Kevin G, Miguel-Aliaga, Irene, Yeo, Giles S H, Dhillo, Waljit S, Owen, Bryn M
Published in Nature communications (29.05.2023)
Published in Nature communications (29.05.2023)
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Journal Article