Blood Neutrophils Are Reprogrammed in Bronchiectasis
Bedi, Pallavi, Davidson, Donald J, McHugh, Brian J, Rossi, Adriano G, Hill, Adam T
Published in American journal of respiratory and critical care medicine (01.10.2018)
Published in American journal of respiratory and critical care medicine (01.10.2018)
Get full text
Journal Article
Short- and Long-Term Antibiotic Treatment Reduces Airway and Systemic Inflammation in Non―Cystic Fibrosis Bronchiectasis
CHALMERS, James D, SMITH, Maeve P, MCHUGH, Brian J, DOHERTY, Cathy, GOVAN, John R, HILL, Adam T
Published in American journal of respiratory and critical care medicine (01.10.2012)
Published in American journal of respiratory and critical care medicine (01.10.2012)
Get full text
Journal Article
The human cathelicidin LL-37 has antiviral activity against respiratory syncytial virus
Currie, Silke M, Findlay, Emily Gwyer, McHugh, Brian J, Mackellar, Annie, Man, Tian, Macmillan, Derek, Wang, Hongwei, Fitch, Paul M, Schwarze, Jürgen, Davidson, Donald J
Published in PloS one (30.08.2013)
Published in PloS one (30.08.2013)
Get full text
Journal Article
Microbial Host Interactions and Impaired Wound Healing in Mice and Humans: Defining a Role for BD14 and NOD2
Williams, Helen, Campbell, Laura, Crompton, Rachel A., Singh, Gurdeep, McHugh, Brian J., Davidson, Donald J., McBain, Andrew J., Cruickshank, Sheena M., Hardman, Matthew J.
Published in Journal of investigative dermatology (01.10.2018)
Published in Journal of investigative dermatology (01.10.2018)
Get full text
Journal Article
A mechanistic evaluation of human beta defensin 2 mediated protection of human skin barrier in vitro
Shelley, Jennifer R., McHugh, Brian J., Wills, Jimi, Dorin, Julia R., Weller, Richard, Clarke, David J., Davidson, Donald J.
Published in Scientific reports (08.02.2023)
Published in Scientific reports (08.02.2023)
Get full text
Journal Article
The antimicrobial peptide cathelicidin drives development of experimental autoimmune encephalomyelitis in mice by affecting Th17 differentiation
Smith, Katie J, Minns, Danielle, McHugh, Brian J, Holloway, Rebecca K, O'Connor, Richard, Williams, Anna, Melrose, Lauren, McPherson, Rhoanne, Miron, Veronique E, Davidson, Donald J, Gwyer Findlay, Emily
Published in PLoS biology (26.08.2022)
Published in PLoS biology (26.08.2022)
Get full text
Journal Article
Cathelicidin is a "fire alarm", generating protective NLRP3-dependent airway epithelial cell inflammatory responses during infection with Pseudomonas aeruginosa
McHugh, Brian J, Wang, Rongling, Li, Hsin-Ni, Beaumont, Paula E, Kells, Rebekah, Stevens, Holly, Young, Lisa, Rossi, Adriano G, Gray, Robert D, Dorin, Julia R, Gwyer Findlay, Emily L, Brough, David, Davidson, Donald J
Published in PLoS pathogens (12.04.2019)
Published in PLoS pathogens (12.04.2019)
Get full text
Journal Article
Galectin-3 inhibitor GB0139 protects against acute lung injury by inhibiting neutrophil recruitment and activation
Humphries, Duncan C., Mills, Ross, Boz, Cecilia, McHugh, Brian J., Hirani, Nikhil, Rossi, Adriano G., Pedersen, Anders, Schambye, Hans T., Slack, Robert J., Leffler, Hakon, Nilsson, Ulf J., Wang, Wei, Sethi, Tariq, Mackinnon, Alison C.
Published in Frontiers in pharmacology (08.08.2022)
Published in Frontiers in pharmacology (08.08.2022)
Get full text
Journal Article
Mannose-binding lectin deficiency and disease severity in non-cystic fibrosis bronchiectasis: a prospective study
Chalmers, James D, McHugh, Brian J, Doherty, Catherine, Smith, Maeve P, Govan, John R, Kilpatrick, David C, Hill, Adam T
Published in The lancet respiratory medicine (01.05.2013)
Published in The lancet respiratory medicine (01.05.2013)
Get more information
Journal Article
A fluorogenic, peptide-based probe for the detection of Cathepsin D in macrophages
Rodriguez-Rios, Maria, McHugh, Brian J., Liang, Zhengqi, Megia-Fernandez, Alicia, Lilienkampf, Annamaria, Dockrell, David, Bradley, Mark
Published in Communications chemistry (02.11.2023)
Published in Communications chemistry (02.11.2023)
Get full text
Journal Article
Human cathelicidin production by the cervix
Frew, Lorraine, Makieva, Sofia, McKinlay, Andrew T M, McHugh, Brian J, Doust, Ann, Norman, Jane E, Davidson, Donald J, Stock, Sarah J
Published in PloS one (04.08.2014)
Published in PloS one (04.08.2014)
Get full text
Journal Article
Exposure to the antimicrobial peptide LL-37 produces dendritic cells optimized for immunotherapy
Findlay, Emily Gwyer, Currie, Andrew J., Zhang, Ailiang, Ovciarikova, Jana, Young, Lisa, Stevens, Holly, McHugh, Brian J., Canel, Marta, Gray, Mohini, Milling, Simon W.F., Campbell, John D.M., Savill, John, Serrels, Alan, Davidson, Donald J.
Published in Oncoimmunology (03.08.2019)
Published in Oncoimmunology (03.08.2019)
Get full text
Journal Article
Inhibition of Cyclin-Dependent Kinase 9 Downregulates Cytokine Production Without Detrimentally Affecting Human Monocyte-Derived Macrophage Viability
McHugh, Brian J, Stephen, Jillian, Robb, Calum T, Fox, Sarah, Kipari, Tiina, Cartwright, Jennifer A, Haslett, Christopher, Duffin, Rodger, Lucas, Christopher D, Rossi, Adriano G
Published in Frontiers in cell and developmental biology (26.05.2022)
Published in Frontiers in cell and developmental biology (26.05.2022)
Get full text
Journal Article
Cost analysis of anterior-posterior circumferential fusion and transforaminal lumbar interbody fusion
Andres, Tate M., BS, Park, Justin J., MD, Ricart Hoffiz, Pedro A., MD, McHugh, Brian J., MD, Warren, Daniel T., MD, Errico, Thomas J., MD
Published in The spine journal (01.06.2013)
Published in The spine journal (01.06.2013)
Get full text
Journal Article
An Orally Active Galectin-3 Antagonist Inhibits Lung Adenocarcinoma Growth and Augments Response to PD-L1 Blockade
Vuong, Lynda, Kouverianou, Eleni, Rooney, Claire M, McHugh, Brian J, Howie, Sarah E M, Gregory, Christopher D, Forbes, Stuart J, Henderson, Neil C, Zetterberg, Fredrik R, Nilsson, Ulf J, Leffler, Hakon, Ford, Paul, Pedersen, Anders, Gravelle, Lise, Tantawi, Susan, Schambye, Hans, Sethi, Tariq, MacKinnon, Alison C
Published in Cancer research (Chicago, Ill.) (01.04.2019)
Published in Cancer research (Chicago, Ill.) (01.04.2019)
Get full text
Journal Article
Vitamin-D deficiency is associated with chronic bacterial colonisation and disease severity in bronchiectasis
Chalmers, James D, McHugh, Brian J, Docherty, Catherine, Govan, John R W, Hill, Adam T
Published in Thorax (01.01.2013)
Published in Thorax (01.01.2013)
Get full text
Journal Article
NRF2 Activation Reprograms Defects in Oxidative Metabolism to Restore Macrophage Function in Chronic Obstructive Pulmonary Disease
Ryan, Eilise M, Sadiku, Pranvera, Coelho, Patricia, Watts, Emily R, Zhang, Ailiang, Howden, Andrew J M, Sanchez-Garcia, Manuel A, Bewley, Martin, Cole, Joby, McHugh, Brian J, Vermaelen, Wesley, Ghesquiere, Bart, Carmeliet, Peter, Rodriguez Blanco, Giovanny, Von Kriegsheim, Alex, Sanchez, Yolanda, Rumsey, William, Callahan, James F, Cooper, George, Parkinson, Nicholas, Baillie, Kenneth, Cantrell, Doreen A, McCafferty, John, Choudhury, Gourab, Singh, Dave, Dockrell, David H, Whyte, Moira K B, Walmsley, Sarah R
Published in American journal of respiratory and critical care medicine (15.04.2023)
Published in American journal of respiratory and critical care medicine (15.04.2023)
Get full text
Journal Article