Genome wide association study of silent cerebral infarction in sickle cell disease (HbSS and HbSC)
Brewin, John N, Rooks, Helen, Gardner, Kate, Senior, Harry, Morje, Mrinmayi, Patel, Hamel, Calvet, David, Bartolucci, Pablo, Thein, Swee-Lay, Menzel, Stephan, Rees, David C
Published in Haematologica (Roma) (01.06.2021)
Published in Haematologica (Roma) (01.06.2021)
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Human cellular model systems of β-thalassemia enable in-depth analysis of disease phenotype
Daniels, Deborah E, Ferrer-Vicens, Ivan, Hawksworth, Joseph, Andrienko, Tatyana N, Finnie, Elizabeth M, Bretherton, Natalie S, Ferguson, Daniel C J, Oliveira, A Sofia F, Szeto, Jenn-Yeu A, Wilson, Marieangela C, Brewin, John N, Frayne, Jan
Published in Nature communications (06.10.2023)
Published in Nature communications (06.10.2023)
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The erythrocyte membrane properties of beta thalassaemia heterozygotes and their consequences for Plasmodium falciparum invasion
Introini, Viola, Marin-Menendez, Alejandro, Nettesheim, Guilherme, Lin, Yen-Chun, Kariuki, Silvia N, Smith, Adrian L, Jean, Letitia, Brewin, John N, Rees, David C, Cicuta, Pietro, Rayner, Julian C, Penman, Bridget S
Published in Scientific reports (27.05.2022)
Published in Scientific reports (27.05.2022)
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Journal Article
Automating Pitted Red Blood Cell Counts Using Deep Neural Network Analysis: A New Method for Measuring Splenic Function in Sickle Cell Anaemia
Nardo-Marino, Amina, Braunstein, Thomas H, Petersen, Jesper, Brewin, John N, Mottelson, Mathis N, Williams, Thomas N, Kurtzhals, Jørgen A L, Rees, David C, Glenthøj, Andreas
Published in Frontiers in physiology (05.04.2022)
Published in Frontiers in physiology (05.04.2022)
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Journal Article
Pathophysiological Relevance of Renal Medullary Conditions on the Behaviour of Red Cells From Patients With Sickle Cell Anaemia
Lu, David C-Y, Wadud, Rasiqh, Hannemann, Anke, Rees, David C, Brewin, John N, Gibson, John Stanley
Published in Frontiers in physiology (19.03.2021)
Published in Frontiers in physiology (19.03.2021)
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Journal Article
The effect of the antisickling compound GBT1118 on the permeability of red blood cells from patients with sickle cell anemia
Al Balushi, Halima, Dufu, Kobina, Rees, David C., Brewin, John N., Hannemann, Anke, Oksenberg, Donna, Lu, David C.‐Y., Gibson, John S.
Published in Physiological reports (01.03.2019)
Published in Physiological reports (01.03.2019)
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Journal Article
Oxygen gradient ektacytometry does not predict pain in children with sickle cell anaemia
Nardo‐Marino, Amina, Petersen, Jesper, Brewin, John N., Birgens, Henrik, Williams, Thomas N., Kurtzhals, Jørgen A. L., Rees, David C., Glenthøj, Andreas
Published in British journal of haematology (01.06.2022)
Published in British journal of haematology (01.06.2022)
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Journal Article
The pleiotropic effects of α‐thalassemia on HbSS and HbSC sickle cell disease: Reduced erythrocyte cation co‐transport activity, serum erythropoietin, and transfusion burden, do not translate into increased survival
Brewin, John N., Nardo‐Marino, Amina, Stuart‐Smith, Sara, El Hoss, Sara, Hanneman, Anke, Strouboulis, John, Menzel, Stephan, Gibson, John S., Rees, David C.
Published in American journal of hematology (01.10.2022)
Published in American journal of hematology (01.10.2022)
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Journal Article
The significance of spleen size in children with sickle cell anemia
Nardo‐Marino, Amina, Glenthøj, Andreas, Brewin, John N., Petersen, Jesper, Braunstein, Thomas H., Kurtzhals, Jørgen A. L., Williams, Thomas N., Rees, David C.
Published in American journal of hematology (01.12.2022)
Published in American journal of hematology (01.12.2022)
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Journal Article
Catheter associated thromboses in patients with sickle cell anaemia and dual lumen Vortex apheresis ports are common and can be clinically asymptomatic
Brewin, John N., Crowley, Maeve P., Kesse‐Adu, Rachel, Stuart‐Smith, Sara, Awogbade, Moji, Howard, Jo
Published in British journal of haematology (01.06.2020)
Published in British journal of haematology (01.06.2020)
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Journal Article
Males with sickle cell disease have higher risks of cerebrovascular disease, increased inflammation, and a reduced response to hydroxyurea
Di Mauro, Margherita, El Hoss, Sara, Nardo-Marino, Amina, Stuart-Smith, Sara, Strouboulis, John, Gibson, John S, Rees, David C, Brewin, John N
Published in American journal of hematology (01.11.2023)
Published in American journal of hematology (01.11.2023)
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Journal Article
The role of WNK in modulation of KCl cotransport activity in red cells from normal individuals and patients with sickle cell anaemia
Lu, David C.-Y., Hannemann, Anke, Wadud, Rasiqh, Rees, David C., Brewin, John N., Low, Philip S., Gibson, John S.
Published in Pflügers Archiv (01.12.2019)
Published in Pflügers Archiv (01.12.2019)
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Evaluation of oxidative stress-related genetic variants for predicting stroke in patients with sickle cell anemia
Domingos, Igor F., Pereira-Martins, Diego A., Borges-Medeiros, Rayssa L., Falcao, Diego A., Hatzlhofer, Betania L., Brewin, John N., Gardner, Kate, Mendonca, Taciana F., Cavalcanti, Maria S., Cunha, Anderson F., Anjos, Ana C., Rodrigues, Evandra S., Kashima, Simone, Cruz, Pedro R., Melo, Monica B., Menzel, Stephan, Araujo, Aderson S., Costa, Fernando F., Bezerra, Marcos A., Lucena-Araujo, Antonio R.
Published in Journal of the neurological sciences (15.07.2020)
Published in Journal of the neurological sciences (15.07.2020)
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Journal Article
The super sickling haemoglobin HbS‐Oman: a study of red cell sickling, K+ permeability and associations with disease severity in patients heterozygous for HbA and HbS‐Oman (HbA/S‐Oman genotype)
Al Balushi, Halima W. M., Wali, Yasser, Al Awadi, Maha, Al‐Subhi, Taimoora, Rees, David C., Brewin, John N., Hannemann, Anke, Gibson, John S.
Published in British journal of haematology (01.10.2017)
Published in British journal of haematology (01.10.2017)
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Journal Article
Genetic Analysis of Patients With Sickle Cell Anemia and Stroke Before 4 Years of Age Suggest an Important Role for Apoliprotein E
Brewin, John N, Smith, Alexander E, Cook, Riley, Tewari, Sanjay, Brent, Julie, Wilkinson, Sarah, Brousse, Valentine, Inusa, Baba, Menzel, Stephan, Rees, David C
Published in Circulation. Genomic and precision medicine (01.10.2020)
Published in Circulation. Genomic and precision medicine (01.10.2020)
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Journal Article
The effect of the antisickling compound GBT 1118 on the permeability of red blood cells from patients with sickle cell anemia
Al Balushi, Halima, Dufu, Kobina, Rees, David C., Brewin, John N., Hannemann, Anke, Oksenberg, Donna, Lu, David C.‐Y., Gibson, John S.
Published in Physiological reports (01.03.2019)
Published in Physiological reports (01.03.2019)
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