E-cadherin-deficient cells have synthetic lethal vulnerabilities in plasma membrane organisation, dynamics and function
Godwin, Tanis D., Kelly, S. Thomas, Brew, Tom P., Bougen-Zhukov, Nicola M., Single, Andrew B., Chen, Augustine, Stylianou, Cassie E., Harris, Lawrence D., Currie, Sophie K., Telford, Bryony J., Beetham, Henry G., Evans, Gary B., Black, Michael A., Guilford, Parry J.
Published in Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association (01.03.2019)
Published in Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association (01.03.2019)
Get full text
Journal Article
E-Cadherin-Deficient Epithelial Cells Are Sensitive to HDAC Inhibitors
Decourtye-Espiard, Lyvianne, Bougen-Zhukov, Nicola, Godwin, Tanis, Brew, Tom, Schulpen, Emily, Black, Michael A, Guilford, Parry
Published in Cancers (30.12.2021)
Published in Cancers (30.12.2021)
Get full text
Journal Article
Synthetic Lethal Screens Identify Vulnerabilities in GPCR Signaling and Cytoskeletal Organization in E-Cadherin-Deficient Cells
Telford, Bryony J, Chen, Augustine, Beetham, Henry, Frick, James, Brew, Tom P, Gould, Cathryn M, Single, Andrew, Godwin, Tanis, Simpson, Kaylene J, Guilford, Parry
Published in Molecular cancer therapeutics (01.05.2015)
Published in Molecular cancer therapeutics (01.05.2015)
Get full text
Journal Article
Loss of E-Cadherin Leads to Druggable Vulnerabilities in Sphingolipid Metabolism and Vesicle Trafficking
Brew, Tom, Bougen-Zhukov, Nicola, Mitchell, Wilson, Decourtye, Lyvianne, Schulpen, Emily, Nouri, Yasmin, Godwin, Tanis, Guilford, Parry
Published in Cancers (26.12.2021)
Published in Cancers (26.12.2021)
Get full text
Journal Article
Allosteric AKT Inhibitors Target Synthetic Lethal Vulnerabilities in E-Cadherin-Deficient Cells
Bougen-Zhukov, Nicola, Nouri, Yasmin, Godwin, Tanis, Taylor, Megan, Hakkaart, Christopher, Single, Andrew, Brew, Tom, Permina, Elizabeth, Chen, Augustine, Black, Michael A., Guilford, Parry
Published in Cancers (13.09.2019)
Published in Cancers (13.09.2019)
Get full text
Journal Article
Hereditary diffuse gastric cancer: updated clinical practice guidelines
Blair, Vanessa R, McLeod, Maybelle, Carneiro, Fátima, Coit, Daniel G, D'Addario, Johanna L, van Dieren, Jolanda M, Harris, Kirsty L, Hoogerbrugge, Nicoline, Oliveira, Carla, van der Post, Rachel S, Arnold, Julie, Benusiglio, Patrick R, Bisseling, Tanya M, Boussioutas, Alex, Cats, Annemieke, Charlton, Amanda, Schreiber, Karen E Chelcun, Davis, Jeremy L, Pietro, Massimiliano di, Fitzgerald, Rebecca C, Ford, James M, Gamet, Kimberley, Gullo, Irene, Hardwick, Richard H, Huntsman, David G, Kaurah, Pardeep, Kupfer, Sonia S, Latchford, Andrew, Mansfield, Paul F, Nakajima, Takeshi, Parry, Susan, Rossaak, Jeremy, Sugimura, Haruhiko, Svrcek, Magali, Tischkowitz, Marc, Ushijima, Toshikazu, Yamada, Hidetaka, Yang, Han-Kwang, Claydon, Adrian, Figueiredo, Joana, Paringatai, Karyn, Seruca, Raquel, Bougen-Zhukov, Nicola, Brew, Tom, Busija, Simone, Carneiro, Patricia, DeGregorio, Lynn, Fisher, Helen, Gardner, Erin, Godwin, Tanis D, Holm, Katharine N, Humar, Bostjan, Lintott, Caroline J, Monroe, Elizabeth C, Muller, Mark D, Norero, Enrique, Nouri, Yasmin, Paredes, Joana, Sanches, João M, Schulpen, Emily, Ribeiro, Ana S, Sporle, Andrew, Whitworth, James, Zhang, Liying, Reeve, Anthony E, Guilford, Parry
Published in The lancet oncology (01.08.2020)
Published in The lancet oncology (01.08.2020)
Get full text
Journal Article
Modelling hereditary diffuse gastric cancer initiation using transgenic mouse‐derived gastric organoids and single‐cell sequencing
Dixon, Katherine, Brew, Tom, Farnell, David, Godwin, Tanis D, Cheung, Simon, Chow, Christine, Ta, Monica, Ho, Germain, Bui, Minh, Douglas, J Maxwell, Campbell, Kieran R, El‐Naggar, Amal, Kaurah, Pardeep, Kalloger, Steve E, Lim, Howard J, Schaeffer, David F, Cochrane, Dawn, Guilford, Parry, Huntsman, David G
Published in The Journal of pathology (01.07.2021)
Published in The Journal of pathology (01.07.2021)
Get full text
Journal Article