De novo design of picomolar SARS-CoV-2 miniprotein inhibitors
Cao, Longxing, Goreshnik, Inna, Coventry, Brian, Case, James Brett, Miller, Lauren, Kozodoy, Lisa, Chen, Rita E, Carter, Lauren, Walls, Alexandra C, Park, Young-Jun, Strauch, Eva-Maria, Stewart, Lance, Diamond, Michael S, Veesler, David, Baker, David
Published in Science (23.10.2020)
Published in Science (23.10.2020)
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Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody
Pinto, Dora, Park, Young-Jun, Beltramello, Martina, Walls, Alexandra C., Tortorici, M. Alejandra, Bianchi, Siro, Jaconi, Stefano, Culap, Katja, Zatta, Fabrizia, De Marco, Anna, Peter, Alessia, Guarino, Barbara, Spreafico, Roberto, Cameroni, Elisabetta, Case, James Brett, Chen, Rita E., Havenar-Daughton, Colin, Snell, Gyorgy, Telenti, Amalio, Virgin, Herbert W., Lanzavecchia, Antonio, Diamond, Michael S., Fink, Katja, Veesler, David, Corti, Davide
Published in Nature (London) (09.07.2020)
Published in Nature (London) (09.07.2020)
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Growth, detection, quantification, and inactivation of SARS-CoV-2
Case, James Brett, Bailey, Adam L., Kim, Arthur S., Chen, Rita E., Diamond, Michael S.
Published in Virology (New York, N.Y.) (01.09.2020)
Published in Virology (New York, N.Y.) (01.09.2020)
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Human neutralizing antibodies against SARS-CoV-2 require intact Fc effector functions for optimal therapeutic protection
Winkler, Emma S., Gilchuk, Pavlo, Yu, Jinsheng, Bailey, Adam L., Chen, Rita E., Chong, Zhenlu, Zost, Seth J., Jang, Hyesun, Huang, Ying, Allen, James D., Case, James Brett, Sutton, Rachel E., Carnahan, Robert H., Darling, Tamarand L., Boon, Adrianus C.M., Mack, Matthias, Head, Richard D., Ross, Ted M., Crowe, James E., Diamond, Michael S.
Published in Cell (01.04.2021)
Published in Cell (01.04.2021)
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A SARS-CoV-2 Infection Model in Mice Demonstrates Protection by Neutralizing Antibodies
Hassan, Ahmed O., Case, James Brett, Winkler, Emma S., Thackray, Larissa B., Kafai, Natasha M., Bailey, Adam L., McCune, Broc T., Fox, Julie M., Chen, Rita E., Alsoussi, Wafaa B., Turner, Jackson S., Schmitz, Aaron J., Lei, Tingting, Shrihari, Swathi, Keeler, Shamus P., Fremont, Daved H., Greco, Suellen, McCray, Paul B., Perlman, Stanley, Holtzman, Michael J., Ellebedy, Ali H., Diamond, Michael S.
Published in Cell (06.08.2020)
Published in Cell (06.08.2020)
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Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease
Agostini, Maria L, Andres, Erica L, Sims, Amy C, Graham, Rachel L, Sheahan, Timothy P, Lu, Xiaotao, Smith, Everett Clinton, Case, James Brett, Feng, Joy Y, Jordan, Robert, Ray, Adrian S, Cihlar, Tomas, Siegel, Dustin, Mackman, Richard L, Clarke, Michael O, Baric, Ralph S, Denison, Mark R
Published in mBio (06.03.2018)
Published in mBio (06.03.2018)
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Association between SARS-CoV-2 Neutralizing Antibodies and Commercial Serological Assays
Tang, Mei San, Case, James Brett, Franks, Caroline E, Chen, Rita E, Anderson, Neil W, Henderson, Jeffrey P, Diamond, Michael S, Gronowski, Ann M, Farnsworth, Christopher W
Published in Clinical chemistry (Baltimore, Md.) (01.12.2020)
Published in Clinical chemistry (Baltimore, Md.) (01.12.2020)
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Inhibition of PIKfyve kinase prevents infection by Zaire ebolavirus and SARS-CoV-2
Kang, Yuan-Lin, Chou, Yi-ying, Rothlauf, Paul W., Liu, Zhuoming, Soh, Timothy K., Cureton, David, Case, James Brett, Chen, Rita E., Diamond, Michael S., Whelan, Sean P. J., Kirchhausen, Tom
Published in Proceedings of the National Academy of Sciences - PNAS (25.08.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (25.08.2020)
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Neutralizing Antibody and Soluble ACE2 Inhibition of a Replication-Competent VSV-SARS-CoV-2 and a Clinical Isolate of SARS-CoV-2
Case, James Brett, Rothlauf, Paul W., Chen, Rita E., Liu, Zhuoming, Zhao, Haiyan, Kim, Arthur S., Bloyet, Louis-Marie, Zeng, Qiru, Tahan, Stephen, Droit, Lindsay, Ilagan, Ma. Xenia G., Tartell, Michael A., Amarasinghe, Gaya, Henderson, Jeffrey P., Miersch, Shane, Ustav, Mart, Sidhu, Sachdev, Virgin, Herbert W., Wang, David, Ding, Siyuan, Corti, Davide, Theel, Elitza S., Fremont, Daved H., Diamond, Michael S., Whelan, Sean P.J.
Published in Cell Host & Microbe (09.09.2020)
Published in Cell Host & Microbe (09.09.2020)
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Cholesterol 25-hydroxylase suppresses SARS-CoV-2 replication by blocking membrane fusion
Zang, Ruochen, Case, James Brett, Yutuc, Eylan, Ma, Xiucui, Shen, Sheng, Castro, Maria Florencia Gomez, Liu, Zhuoming, Zeng, Qiru, Zhao, Haiyan, Son, Juhee, Rothlauf, Paul W., Kreutzberger, Alex J. B., Hou, Gaopeng, Zhang, Hu, Bose, Sayantan, Wang, Xin, Vahey, Michael D., Mani, Kartik, Griffiths, William J., Kirchhausen, Tom, Fremont, Daved H., Guo, Haitao, Diwan, Abhinav, Wang, Yuqin, Diamond, Michael S., Whelan, Sean P. J., Ding, Siyuan
Published in Proceedings of the National Academy of Sciences - PNAS (15.12.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (15.12.2020)
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Replication-Competent Vesicular Stomatitis Virus Vaccine Vector Protects against SARS-CoV-2-Mediated Pathogenesis in Mice
Case, James Brett, Rothlauf, Paul W., Chen, Rita E., Kafai, Natasha M., Fox, Julie M., Smith, Brittany K., Shrihari, Swathi, McCune, Broc T., Harvey, Ian B., Keeler, Shamus P., Bloyet, Louis-Marie, Zhao, Haiyan, Ma, Meisheng, Adams, Lucas J., Winkler, Emma S., Holtzman, Michael J., Fremont, Daved H., Whelan, Sean P.J., Diamond, Michael S.
Published in Cell Host & Microbe (09.09.2020)
Published in Cell Host & Microbe (09.09.2020)
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SARS-CoV-2 Causes Lung Infection without Severe Disease in Human ACE2 Knock-In Mice
Winkler, Emma S, Chen, Rita E, Alam, Fahmida, Yildiz, Soner, Case, James Brett, Uccellini, Melissa B, Holtzman, Michael J, Garcia-Sastre, Adolfo, Schotsaert, Michael, Diamond, Michael S
Published in Journal of virology (12.01.2022)
Published in Journal of virology (12.01.2022)
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Resilience of S309 and AZD7442 monoclonal antibody treatments against infection by SARS-CoV-2 Omicron lineage strains
Case, James Brett, Mackin, Samantha, Errico, John M., Chong, Zhenlu, Madden, Emily A., Whitener, Bradley, Guarino, Barbara, Schmid, Michael A., Rosenthal, Kim, Ren, Kuishu, Dang, Ha V., Snell, Gyorgy, Jung, Ana, Droit, Lindsay, Handley, Scott A., Halfmann, Peter J., Kawaoka, Yoshihiro, Crowe, James E., Fremont, Daved H., Virgin, Herbert W., Loo, Yueh-Ming, Esser, Mark T., Purcell, Lisa A., Corti, Davide, Diamond, Michael S.
Published in Nature communications (02.07.2022)
Published in Nature communications (02.07.2022)
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Murine Hepatitis Virus nsp14 Exoribonuclease Activity Is Required for Resistance to Innate Immunity
Case, James Brett, Li, Yize, Elliott, Ruth, Lu, Xiaotao, Graepel, Kevin W, Sexton, Nicole R, Smith, Everett Clinton, Weiss, Susan R, Denison, Mark R
Published in Journal of virology (01.01.2018)
Published in Journal of virology (01.01.2018)
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One-Shot 3D-Printed Multimaterial Soft Robotic Jamming Grippers
Howard, Gerard David, Brett, James, O'Connor, Jack, Letchford, Jordan, Delaney, Gary W
Published in Soft robotics (01.06.2022)
Published in Soft robotics (01.06.2022)
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Apical Dominance and Shoot Branching. Divergent Opinions or Divergent Mechanisms?
Dun, Elizabeth Ann, Ferguson, Brett James, Beveridge, Christine Anne
Published in Plant physiology (Bethesda) (01.11.2006)
Published in Plant physiology (Bethesda) (01.11.2006)
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Enhancing antibody responses by multivalent antigen display on thymus-independent DNA origami scaffolds
Wamhoff, Eike-Christian, Ronsard, Larance, Feldman, Jared, Knappe, Grant A., Hauser, Blake M., Romanov, Anna, Case, James Brett, Sanapala, Shilpa, Lam, Evan C., Denis, Kerri J. St, Boucau, Julie, Barczak, Amy K., Balazs, Alejandro B., Diamond, Michael S., Schmidt, Aaron G., Lingwood, Daniel, Bathe, Mark
Published in Nature communications (30.01.2024)
Published in Nature communications (30.01.2024)
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A single intranasal dose of chimpanzee adenovirus-vectored vaccine protects against SARS-CoV-2 infection in rhesus macaques
Hassan, Ahmed O., Feldmann, Friederike, Zhao, Haiyan, Curiel, David T., Okumura, Atsushi, Tang-Huau, Tsing-Lee, Case, James Brett, Meade-White, Kimberly, Callison, Julie, Chen, Rita E., Lovaglio, Jamie, Hanley, Patrick W., Scott, Dana P., Fremont, Daved H., Feldmann, Heinz, Diamond, Michael S.
Published in Cell reports. Medicine (20.04.2021)
Published in Cell reports. Medicine (20.04.2021)
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An antibody targeting the N-terminal domain of SARS-CoV-2 disrupts the spike trimer
Suryadevara, Naveenchandra, Shiakolas, Andrea R, VanBlargan, Laura A, Binshtein, Elad, Chen, Rita E, Case, James Brett, Kramer, Kevin J, Armstrong, Erica C, Myers, Luke, Trivette, Andrew, Gainza, Christopher, Nargi, Rachel S, Selverian, Christopher N, Davidson, Edgar, Doranz, Benjamin J, Diaz, Summer M, Handal, Laura S, Carnahan, Robert H, Diamond, Michael S, Georgiev, Ivelin S, Crowe, Jr, James E
Published in The Journal of clinical investigation (01.06.2022)
Published in The Journal of clinical investigation (01.06.2022)
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