Comparison of rat and rabbit embryo-fetal developmental toxicity data for 379 pharmaceuticals: on the nature and severity of developmental effects
Theunissen, Peter T., Beken, Sonja, Beyer, Bruce K., Breslin, William J., Cappon, Gregg D., Chen, Connie L., Chmielewski, Gary, De Schaepdrijver, Luc, Enright, Brian, Foreman, Jennifer E., Harrouk, Wafa, Hew, Kok-Wah, Hoberman, Alan M., Hui, Julia Y., Knudsen, Thomas B., Laffan, Susan B., Makris, Susan L., Martin, Matt, McNerney, Mary Ellen, Siezen, Christine L., Stanislaus, Dinesh J., Stewart, Jane, Thompson, Kary E., Tornesi, Belen, Van der Laan, Jan Willem, Weinbauer, Gerhard F., Wood, Sandra, Piersma, Aldert H.
Published in Critical reviews in toxicology (25.11.2016)
Published in Critical reviews in toxicology (25.11.2016)
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Journal Article
Placental Transfer of Fc-Containing Biopharmaceuticals across Species, an Industry Survey Analysis
Bowman, Christopher J., Breslin, William J., Connor, Anu V., Martin, Pauline L., Moffat, Graeme J., Sivaraman, Lakshmi, Tornesi, M. Belen, Chivers, Simon
Published in Birth defects research. Part B. Developmental and reproductive toxicology (01.12.2013)
Published in Birth defects research. Part B. Developmental and reproductive toxicology (01.12.2013)
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Journal Article
Assessment of fetal exposure risk following seminal excretion of a therapeutic IgG4 (T-IgG4) monoclonal antibody using a rabbit model
Breslin, William J., Hilbish, Kim G., Page, Todd J., Coutant, David E.
Published in Reproductive toxicology (Elmsford, N.Y.) (01.09.2014)
Published in Reproductive toxicology (Elmsford, N.Y.) (01.09.2014)
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Journal Article
Potential seminal transport of pharmaceuticals to the conceptus
Scialli, Anthony R., Bailey, Graham, Beyer, Bruce K., Bøgh, Ingrid Brück, Breslin, William J., Chen, Connie L., DeLise, Anthony M., Hui, Julia Y., Moffat, Graeme J., Stewart, Jane, Thompson, Kary E.
Published in Reproductive toxicology (Elmsford, N.Y.) (01.12.2015)
Published in Reproductive toxicology (Elmsford, N.Y.) (01.12.2015)
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Journal Article
Reprint of “Potential seminal transport of pharmaceuticals to the conceptus”
Scialli, Anthony R., Bailey, Graham, Beyer, Bruce K., Bøgh, Ingrid Brück, Breslin, William J., Chen, Connie L., DeLise, Anthony M., Hui, Julia Y., Moffat, Graeme J., Stewart, Jane, Thompson, Kary E.
Published in Reproductive toxicology (Elmsford, N.Y.) (01.01.2016)
Published in Reproductive toxicology (Elmsford, N.Y.) (01.01.2016)
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Journal Article
TGF- beta 1 monoclonal antibody: Assessment of embryo-fetal toxicity in rats and rabbits
Hilbish, Kim G, Martin, Jennifer A, Stauber, Anja J, Edwards, Tammye L, Breslin, William J
Published in Birth defects research. Part B. Developmental and reproductive toxicology (01.08.2016)
Published in Birth defects research. Part B. Developmental and reproductive toxicology (01.08.2016)
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Journal Article
TGF-β1 monoclonal antibody: Assessment of embryo-fetal toxicity in rats and rabbits
Hilbish, Kim G., Martin, Jennifer A., Stauber, Anja J., Edwards, Tammye L., Breslin, William J.
Published in Birth defects research. Part B. Developmental and reproductive toxicology (01.08.2016)
Published in Birth defects research. Part B. Developmental and reproductive toxicology (01.08.2016)
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Journal Article
An Enhanced Pre- and Postnatal Development Study in Cynomolgus Monkeys with Tabalumab: A Human IgG4 Monoclonal Antibody
Breslin, William J., Hilbish, Kim G., Martin, Jennifer A., Halstead, Carolyn A., Newcomb, Deanna L., Chellman, Gary J.
Published in Birth defects research. Part B. Developmental and reproductive toxicology (01.06.2015)
Published in Birth defects research. Part B. Developmental and reproductive toxicology (01.06.2015)
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Journal Article
Introduction to the HESI DART Drugs in Semen Consortium
Chen, Connie L., Beyer, Bruce K., Breslin, William J., DeLise, Anthony M., Hui, Julia Y., Moffat, Graeme J., Thompson, Kary E.
Published in Reproductive toxicology (Elmsford, N.Y.) (01.09.2014)
Published in Reproductive toxicology (Elmsford, N.Y.) (01.09.2014)
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Journal Article
PDGFRα monoclonal antibody: Assessment of embryo-fetal toxicity and time-dependent placental transfer of a murine surrogate antibody of olaratumab in mice
Luffer-Atlas, Debra, Reddy, Vijayapal R, Hilbish, Kim G, Grace, Curtis E, Breslin, William J
Published in Birth defects research (01.11.2018)
Published in Birth defects research (01.11.2018)
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Journal Article
Developmental Toxicity and Fertility Assessment in Rabbits with Tabalumab: A Human IgG4 Monoclonal Antibody
Breslin, William J., Hilbish, Kim G., Martin, Jennifer A., Halstead, Carolyn A., Edwards, Tammy L.
Published in Birth defects research. Part B. Developmental and reproductive toxicology (01.06.2015)
Published in Birth defects research. Part B. Developmental and reproductive toxicology (01.06.2015)
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Journal Article
Incidence and nature of testicular toxicity findings in pharmaceutical development
Sasaki, Jennifer C., Chapin, Robert E., Hall, David Gregory, Breslin, William, Moffit, Jeffrey, Saldutti, Louise, Enright, Brian, Seger, Monica, Jarvi, Keith, Hixon, Mary, Mitchard, Terri, Kim, James H.
Published in Birth defects research. Part B. Developmental and reproductive toxicology (01.12.2011)
Published in Birth defects research. Part B. Developmental and reproductive toxicology (01.12.2011)
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Journal Article
The Inhibin B (InhB) Response to the Testicular Toxicants Mono-2-Ethylhexyl Phthalate (MEHP), 1,3 Dinitrobenzene (DNB), or Carbendazim (CBZ) Following Short-term Repeat Dosing in the Male Rat
Breslin, William J., Paulman, April, Sun-Lin, Denise, Goldstein, Keith M., Derr, Angela
Published in Birth defects research. Part B. Developmental and reproductive toxicology (01.02.2013)
Published in Birth defects research. Part B. Developmental and reproductive toxicology (01.02.2013)
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Journal Article
Fertility and Developmental Toxicity Assessment in Rats and Rabbits with LY500307, a Selective Estrogen Receptor Beta (ERβ) Agonist
Hilbish, Kim G., Breslin, William J., Johnson, Jason T., Sloter, Eddie D.
Published in Birth defects research. Part B. Developmental and reproductive toxicology (01.10.2013)
Published in Birth defects research. Part B. Developmental and reproductive toxicology (01.10.2013)
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Journal Article
Summary of the HESI Consortium Studies Exploring Circulating Inhibin B as a Potential Biomarker of Testis Damage in the Rat
Chapin, Robert, Weinbauer, Gerhard, Thibodeau, Michael S., Sonee, Manisha, Saldutti, Louise Parks, Reagan, William J., Potter, David, Moffit, Jeffrey S., Laffan, Susan, Kim, James H., Goldstein, Richard A., Erdos, Zoltan, Enright, Brian P., Coulson, Michelle, Breslin, William J.
Published in Birth defects research. Part B. Developmental and reproductive toxicology (01.02.2013)
Published in Birth defects research. Part B. Developmental and reproductive toxicology (01.02.2013)
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Journal Article
Comparing rat and rabbit embryo-fetal developmental toxicity data for 379 pharmaceuticals: on systemic dose and developmental effects
Theunissen, Peter T., Beken, Sonia, Beyer, Bruce, Breslin, William J., Cappon, Gregg D., Chen, Connie L., Chmielewski, Gary, de Schaepdrijver, Luc, Enright, Brian, Foreman, Jennifer E., Harrouk, Wafa, Hew, Kok-Wah, Hoberman, Alan M., Y. Hui, Julia, Knudsen, Thomas B., Laffan, Susan B., Makris, Susan L., Martin, Matthew, McNerney, Mary Ellen, Siezen, Christine L., Stanislaus, Dinesh J., Stewart, Jane, Thompson, Kary E., Tornesi, Belen, Van der Laan, Jan Willem, Weinbauer, Gerhard F., Wood, Sandra, Piersma, Aldert H.
Published in Critical reviews in toxicology (28.05.2017)
Published in Critical reviews in toxicology (28.05.2017)
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Potential Estrogenic and Antiestrogenic Activity of the Cyclic Siloxane Octamethylcyclotetrasiloxane (D4) and the Linear Siloxane Hexamethyldisiloxane (HMDS) in Immature Rats Using the Uterotrophic Assay
McKim, James M., Wilga, Paul C., Breslin, William J., Plotzke, Kathy P., Gallavan, Robert H., Meeks, Robert G.
Published in Toxicological sciences (01.09.2001)
Published in Toxicological sciences (01.09.2001)
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