Fibroblast pathology in inflammatory diseases
Wei, Kevin, Nguyen, Hung N, Brenner, Michael B
Published in The Journal of clinical investigation (15.10.2021)
Published in The Journal of clinical investigation (15.10.2021)
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Metabolic reprogramming of natural killer cells in obesity limits antitumor responses
Michelet, Xavier, Dyck, Lydia, Hogan, Andrew, Loftus, Roisin M., Duquette, Danielle, Wei, Kevin, Beyaz, Semir, Tavakkoli, Ali, Foley, Cathriona, Donnelly, Raymond, O’Farrelly, Cliona, Raverdeau, Mathilde, Vernon, Ashley, Pettee, William, O’Shea, Donal, Nikolajczyk, Barbara S., Mills, Kingston H. G., Brenner, Michael B., Finlay, David, Lynch, Lydia
Published in Nature immunology (01.12.2018)
Published in Nature immunology (01.12.2018)
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Distinct fibroblast subsets drive inflammation and damage in arthritis
Croft, Adam P., Campos, Joana, Jansen, Kathrin, Turner, Jason D., Marshall, Jennifer, Attar, Moustafa, Savary, Loriane, Wehmeyer, Corinna, Naylor, Amy J., Kemble, Samuel, Begum, Jenefa, Dürholz, Kerstin, Perlman, Harris, Barone, Francesca, McGettrick, Helen M., Fearon, Douglas T., Wei, Kevin, Raychaudhuri, Soumya, Korsunsky, Ilya, Brenner, Michael B., Coles, Mark, Sansom, Stephen N., Filer, Andrew, Buckley, Christopher D.
Published in Nature (London) (01.06.2019)
Published in Nature (London) (01.06.2019)
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Autocrine Loop Involving IL-6 Family Member LIF, LIF Receptor, and STAT4 Drives Sustained Fibroblast Production of Inflammatory Mediators
Nguyen, Hung N., Noss, Erika H., Mizoguchi, Fumitaka, Huppertz, Christine, Wei, Kevin S., Watts, Gerald F.M., Brenner, Michael B.
Published in Immunity (Cambridge, Mass.) (21.02.2017)
Published in Immunity (Cambridge, Mass.) (21.02.2017)
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Functionally distinct disease-associated fibroblast subsets in rheumatoid arthritis
Mizoguchi, Fumitaka, Slowikowski, Kamil, Wei, Kevin, Marshall, Jennifer L., Rao, Deepak A., Chang, Sook Kyung, Nguyen, Hung N., Noss, Erika H., Turner, Jason D., Earp, Brandon E., Blazar, Philip E., Wright, John, Simmons, Barry P., Donlin, Laura T., Kalliolias, George D., Goodman, Susan M., Bykerk, Vivian P., Ivashkiv, Lionel B., Lederer, James A., Hacohen, Nir, Nigrovic, Peter A., Filer, Andrew, Buckley, Christopher D., Raychaudhuri, Soumya, Brenner, Michael B.
Published in Nature communications (23.02.2018)
Published in Nature communications (23.02.2018)
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Regulatory iNKT cells lack expression of the transcription factor PLZF and control the homeostasis of Treg cells and macrophages in adipose tissue
Lynch, Lydia, Michelet, Xavier, Zhang, Sai, Brennan, Patrick J, Moseman, Ashley, Lester, Chantel, Besra, Gurdyal, Vomhof-Dekrey, Emilie E, Tighe, Mike, Koay, Hui-Fern, Godfrey, Dale I, Leadbetter, Elizabeth A, Sant'Angelo, Derek B, von Andrian, Ulrich, Brenner, Michael B
Published in Nature immunology (01.01.2015)
Published in Nature immunology (01.01.2015)
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Lymphocyte innateness defined by transcriptional states reflects a balance between proliferation and effector functions
Gutierrez-Arcelus, Maria, Teslovich, Nikola, Mola, Alex R., Polidoro, Rafael B., Nathan, Aparna, Kim, Hyun, Hannes, Susan, Slowikowski, Kamil, Watts, Gerald F. M., Korsunsky, Ilya, Brenner, Michael B., Raychaudhuri, Soumya, Brennan, Patrick J.
Published in Nature communications (08.02.2019)
Published in Nature communications (08.02.2019)
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HBEGF + macrophages in rheumatoid arthritis induce fibroblast invasiveness
Kuo, David, Ding, Jennifer, Cohn, Ian S, Zhang, Fan, Wei, Kevin, Rao, Deepak A, Rozo, Cristina, Sokhi, Upneet K, Shanaj, Sara, Oliver, David J, Echeverria, Adriana P, DiCarlo, Edward F, Brenner, Michael B, Bykerk, Vivian P, Goodman, Susan M, Raychaudhuri, Soumya, Rätsch, Gunnar, Ivashkiv, Lionel B, Donlin, Laura T
Published in Science translational medicine (08.05.2019)
Published in Science translational medicine (08.05.2019)
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Lysosomal Trafficking, Antigen Presentation, and Microbial Killing Are Controlled by the Arf-like GTPase Arl8b
Garg, Salil, Sharma, Mahak, Ung, Cindy, Tuli, Amit, Barral, Duarte C., Hava, David L., Veerapen, Natacha, Besra, Gurdyal S., Hacohen, Nir, Brenner, Michael B.
Published in Immunity (Cambridge, Mass.) (26.08.2011)
Published in Immunity (Cambridge, Mass.) (26.08.2011)
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A Rab3a-dependent complex essential for lysosome positioning and plasma membrane repair
Encarnação, Marisa, Espada, Lília, Escrevente, Cristina, Mateus, Denisa, Ramalho, José, Michelet, Xavier, Santarino, Inês, Hsu, Victor W, Brenner, Michael B, Barral, Duarte C, Vieira, Otília V
Published in The Journal of cell biology (20.06.2016)
Published in The Journal of cell biology (20.06.2016)
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Innate invariant NKT cells recognize Mycobacterium tuberculosis-infected macrophages, produce interferon-gamma, and kill intracellular bacteria
Sada-Ovalle, Isabel, Chiba, Asako, Gonzales, Adaena, Brenner, Michael B, Behar, Samuel M
Published in PLoS pathogens (01.12.2008)
Published in PLoS pathogens (01.12.2008)
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Cadherin-11 regulates fibroblast inflammation
Chang, Sook Kyung, Noss, Erika H, Chen, Mei, Gu, Zhizhan, Townsend, Kirk, Grenha, Rosa, Leon, Luis, Lee, Soo Young, Lee, David M, Brenner, Michael B
Published in Proceedings of the National Academy of Sciences - PNAS (17.05.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (17.05.2011)
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Lysosome-Mediated Plasma Membrane Repair Is Dependent on the Small GTPase Arl8b and Determines Cell Death Type in Mycobacterium tuberculosis Infection
Michelet, Xavier, Tuli, Amit, Gan, Huixian, Geadas, Carolina, Sharma, Mahak, Remold, Heinz G, Brenner, Michael B
Published in The Journal of immunology (1950) (01.05.2018)
Published in The Journal of immunology (1950) (01.05.2018)
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Activation of iNKT cells by a distinct constituent of the endogenous glucosylceramide fraction
Brennan, Patrick J., Tatituri, Raju V. V., Heiss, Christian, Watts, Gerald F. M., Hsu, Fong-Fu, Veerapen, Natacha, Cox, Liam R., Azadi, Parastoo, Besra, Gurdyal S., Brenner, Michael B.
Published in Proceedings of the National Academy of Sciences - PNAS (16.09.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (16.09.2014)
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A Two-Cell Model for IL-1β Release Mediated by Death-Receptor Signaling
Donado, Carlos A., Cao, Anh B., Simmons, Daimon P., Croker, Ben A., Brennan, Patrick J., Brenner, Michael B.
Published in Cell reports (Cambridge) (07.04.2020)
Published in Cell reports (Cambridge) (07.04.2020)
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NK T cells provide lipid antigen-specific cognate help for B cells
Leadbetter, Elizabeth A, Brigl, Manfred, Illarionov, Petr, Cohen, Nadia, Luteran, Megan C, Pillai, Shiv, Besra, Gurdyal S, Brenner, Michael B
Published in Proceedings of the National Academy of Sciences - PNAS (17.06.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (17.06.2008)
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