Tonic 4-1BB Costimulation in Chimeric Antigen Receptors Impedes T Cell Survival and Is Vector-Dependent
Gomes-Silva, Diogo, Mukherjee, Malini, Srinivasan, Madhuwanti, Krenciute, Giedre, Dakhova, Olga, Zheng, Yueting, Cabral, Joaquim M.S., Rooney, Cliona M., Orange, Jordan S., Brenner, Malcolm K., Mamonkin, Maksim
Published in Cell reports (Cambridge) (03.10.2017)
Published in Cell reports (Cambridge) (03.10.2017)
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Tumor response and endogenous immune reactivity after administration of HER2 CAR T cells in a child with metastatic rhabdomyosarcoma
Hegde, Meenakshi, Joseph, Sujith K., Pashankar, Farzana, DeRenzo, Christopher, Sanber, Khaled, Navai, Shoba, Byrd, Tiara T., Hicks, John, Xu, Mina L., Gerken, Claudia, Kalra, Mamta, Robertson, Catherine, Zhang, Huimin, Shree, Ankita, Mehta, Birju, Dakhova, Olga, Salsman, Vita S., Grilley, Bambi, Gee, Adrian, Dotti, Gianpietro, Heslop, Helen E., Brenner, Malcolm K., Wels, Winfried S., Gottschalk, Stephen, Ahmed, Nabil
Published in Nature communications (15.07.2020)
Published in Nature communications (15.07.2020)
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Inducible Apoptosis as a Safety Switch for Adoptive Cell Therapy
Di Stasi, Antonio, Tey, Siok-Keen, Dotti, Gianpietro, Fujita, Yuriko, Kennedy-Nasser, Alana, Martinez, Caridad, Straathof, Karin, Liu, Enli, Liu, Hao, Durett, April G, Grilley, Bambi, Cruz, Conrad R, Savoldo, Barbara, Gee, Adrian P, Schindler, John, Krance, Robert A, Heslop, Helen E, Spencer, David M, Rooney, Cliona M, Brenner, Malcolm K
Published in The New England journal of medicine (03.11.2011)
Published in The New England journal of medicine (03.11.2011)
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Chimeric Antigen Receptors for T-Cell Malignancies
Scherer, Lauren D, Brenner, Malcolm K, Mamonkin, Maksim
Published in Frontiers in oncology (05.03.2019)
Published in Frontiers in oncology (05.03.2019)
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Targeting glycans for CAR therapy: The advent of sweet CARs
Raglow, Zoe, McKenna, Mary Kathryn, Bonifant, Challice L., Wang, Wenjing, Pasca di Magliano, Marina, Stadlmann, Johannes, Penninger, Josef M., Cummings, Richard D., Brenner, Malcolm K., Markovitz, David M.
Published in Molecular therapy (07.09.2022)
Published in Molecular therapy (07.09.2022)
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Allogeneic, off-the-shelf, SARS-CoV-2-specific T cells (ALVR109) for the treatment of COVID-19 in high-risk patients
Vasileiou, Spyridoula, Hill, LaQuisa, Kuvalekar, Manik, Workineh, Aster G, Watanabe, Ayumi, Velazquez, Yovana, Lulla, Suhasini, Mooney, Kimberly, Lapteva, Natalia, Grilley, Bambi J, Heslop, Helen E, Rooney, Cliona M, Brenner, Malcolm K, Eagar, Todd N, Carrum, George, Grimes, Kevin A, Leen, Ann M, Lulla, Premal
Published in Haematologica (Roma) (01.07.2023)
Published in Haematologica (Roma) (01.07.2023)
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CAR T cell therapy for breast cancer: harnessing the tumor milieu to drive T cell activation
Bajgain, Pradip, Tawinwung, Supannikar, D'Elia, Lindsey, Sukumaran, Sujita, Watanabe, Norihiro, Hoyos, Valentina, Lulla, Premal, Brenner, Malcolm K, Leen, Ann M, Vera, Juan F
Published in Journal for immunotherapy of cancer (10.05.2018)
Published in Journal for immunotherapy of cancer (10.05.2018)
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Serial Activation of the Inducible Caspase 9 Safety Switch After Human Stem Cell Transplantation
Zhou, Xiaoou, Naik, Swati, Dakhova, Olga, Dotti, Gianpietro, Heslop, Helen E., Brenner, Malcolm K.
Published in Molecular therapy (01.04.2016)
Published in Molecular therapy (01.04.2016)
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Is cancer gene therapy an empty suit?
Brenner, Malcolm K, Prof Dr, Gottschalk, Stephen, Prof, Leen, Ann M, PhD, Vera, Juan F, MD
Published in The lancet oncology (01.10.2013)
Published in The lancet oncology (01.10.2013)
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A Safeguard System for Induced Pluripotent Stem Cell-Derived Rejuvenated T Cell Therapy
Ando, Miki, Nishimura, Toshinobu, Yamazaki, Satoshi, Yamaguchi, Tomoyuki, Kawana-Tachikawa, Ai, Hayama, Tomonari, Nakauchi, Yusuke, Ando, Jun, Ota, Yasunori, Takahashi, Satoshi, Nishimura, Ken, Ohtaka, Manami, Nakanishi, Mahito, Miles, John J., Burrows, Scott R., Brenner, Malcolm K., Nakauchi, Hiromitsu
Published in Stem cell reports (13.10.2015)
Published in Stem cell reports (13.10.2015)
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Immunotherapy of Metastatic Melanoma Using Genetically Engineered GD2-Specific T cells
YVON, Eric, DEL VECCHIO, Michele, SAVOLDO, Barbara, HOYOS, Valentina, DUTOUR, Aurélie, ANICHINI, Andrea, DOTTI, Gianpietro, BRENNER, Malcolm K
Published in Clinical cancer research (15.09.2009)
Published in Clinical cancer research (15.09.2009)
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Novel banana lectin CAR-T cells to target pancreatic tumors and tumor-associated stroma
McKenna, Mary K, Ozcan, Ada, Brenner, Daniel, Watanabe, Norihiro, Legendre, Maureen, Thomas, Dafydd G, Ashwood, Christopher, Cummings, Richard D, Bonifant, Challice, Markovitz, David M, Brenner, Malcolm K
Published in Journal for immunotherapy of cancer (01.01.2023)
Published in Journal for immunotherapy of cancer (01.01.2023)
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Mesenchymal stromal cells protect combined oncolytic and helper-dependent adenoviruses from humoral immunity
Özcan, Ada Irmak, Aquino Lόpez, Arianexys, Wolff, Alexandra N., Ma, Audrey, Shaw, Amanda Rosewell, Suzuki, Masataka, Brenner, Malcolm K., McKenna, Mary K.
Published in Molecular therapy. Methods & clinical development (12.09.2024)
Published in Molecular therapy. Methods & clinical development (12.09.2024)
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Immunotherapeutic strategies to prevent and treat human herpesvirus 6 reactivation after allogeneic stem cell transplantation
Gerdemann, Ulrike, Keukens, Laura, Keirnan, Jacqueline M., Katari, Usha L., Nguyen, Chinh T.Q., de Pagter, Anne P., Ramos, Carlos A., Kennedy-Nasser, Alana, Gottschalk, Stephen M., Heslop, Helen E., Brenner, Malcolm K., Rooney, Cliona M., Leen, Ann M.
Published in Blood (03.01.2013)
Published in Blood (03.01.2013)
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Identification of Hexon-Specific CD4 and CD8 T-Cell Epitopes for Vaccine and Immunotherapy
LEEN, Ann M, CHRISTIN, Anne, KHALIL, Mariam, WEISS, Heidi, GEE, Adrian P, BRENNER, Malcolm K, HESLOP, Helen E, ROONEY, Cliona M, BOLLARD, Catherine M
Published in Journal of Virology (01.01.2008)
Published in Journal of Virology (01.01.2008)
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Naive T cells inhibit the outgrowth of intractable antigen-activated memory T cells: implications for T-cell immunotherapy
Sharma, Sandhya, Woods, Mae, Mehta, Naren U, Sauer, Tim, Parikh, Kathan S, Schmuck-Henneresse, Michael, Zhang, Huimin, Mehta, Birju, Brenner, Malcolm K, Heslop, Helen E, Rooney, Cliona M
Published in Journal for immunotherapy of cancer (01.04.2023)
Published in Journal for immunotherapy of cancer (01.04.2023)
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Modulating TNFα activity allows transgenic IL15-Expressing CLL-1 CAR T cells to safely eliminate acute myeloid leukemia
Ataca Atilla, Pinar, McKenna, Mary K, Tashiro, Haruko, Srinivasan, Madhuwanti, Mo, Feiyan, Watanabe, Norihiro, Simons, Brian Wesley, McLean Stevens, Alexandra, Redell, Michele S, Heslop, Helen E, Mamonkin, Maksim, Brenner, Malcolm K, Atilla, Erden
Published in Journal for immunotherapy of cancer (01.09.2020)
Published in Journal for immunotherapy of cancer (01.09.2020)
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An Inducible Caspase 9 Suicide Gene to Improve the Safety of Mesenchymal Stromal Cell Therapies
Ramos, Carlos Almeida, Asgari, Zahra, Liu, Enli, Yvon, Eric, Heslop, Helen E., Rooney, Clio M., Brenner, Malcolm K., Dotti, Gianpietro
Published in Stem cells (Dayton, Ohio) (01.06.2010)
Published in Stem cells (Dayton, Ohio) (01.06.2010)
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