Red blood cell-hitchhiking boosts delivery of nanocarriers to chosen organs by orders of magnitude
Brenner, Jacob S., Pan, Daniel C., Myerson, Jacob W., Marcos-Contreras, Oscar A., Villa, Carlos H., Patel, Priyal, Hekierski, Hugh, Chatterjee, Shampa, Tao, Jian-Qin, Parhiz, Hamideh, Bhamidipati, Kartik, Uhler, Thomas G., Hood, Elizabeth D., Kiseleva, Raisa Yu, Shuvaev, Vladimir S., Shuvaeva, Tea, Khoshnejad, Makan, Johnston, Ian, Gregory, Jason V., Lahann, Joerg, Wang, Tao, Cantu, Edward, Armstead, William M., Mitragotri, Samir, Muzykantov, Vladimir
Published in Nature communications (11.07.2018)
Published in Nature communications (11.07.2018)
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Journal Article
PECAM-1 directed re-targeting of exogenous mRNA providing two orders of magnitude enhancement of vascular delivery and expression in lungs independent of apolipoprotein E-mediated uptake
Parhiz, Hamideh, Shuvaev, Vladimir V., Pardi, Norbert, Khoshnejad, Makan, Kiseleva, Raisa Yu, Brenner, Jacob S., Uhler, Thomas, Tuyishime, Steven, Mui, Barbara L., Tam, Ying K., Madden, Thomas D., Hope, Michael J., Weissman, Drew, Muzykantov, Vladimir R.
Published in Journal of controlled release (10.12.2018)
Published in Journal of controlled release (10.12.2018)
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Journal Article
Selective targeting of nanomedicine to inflamed cerebral vasculature to enhance the blood–brain barrier
Marcos-Contreras, Oscar A., Greineder, Colin F., Kiseleva, Raisa Yu, Parhiz, Hamideh, Walsh, Landis R., Zuluaga-Ramirez, Viviana, Myerson, Jacob W., Hood, Elizabeth D., Villa, Carlos H., Tombacz, Istvan, Pardi, Norbert, Seliga, Alecia, Mui, Barbara L., Tam, Ying K., Glassman, Patrick M., Shuvaev, Vladimir V., Nong, Jia, Brenner, Jacob S., Khoshnejad, Makan, Madden, Tom, Weissmann, Drew, Persidsky, Yuri, Muzykantov, Vladimir R.
Published in Proceedings of the National Academy of Sciences - PNAS (18.02.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (18.02.2020)
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Journal Article
Added to pre-existing inflammation, mRNA-lipid nanoparticles induce inflammation exacerbation (IE)
Parhiz, Hamideh, Brenner, Jacob S., Patel, Priyal N., Papp, Tyler E., Shahnawaz, Hamna, Li, Qin, Shi, Ruiqi, Zamora, Marco E., Yadegari, Amir, Marcos-Contreras, Oscar A., Natesan, Ambika, Pardi, Norbert, Shuvaev, Vladimir V., Kiseleva, Raisa, Myerson, Jacob W., Uhler, Thomas, Riley, Rachel S., Han, Xuexiang, Mitchell, Michael J., Lam, Kieu, Heyes, James, Weissman, Drew, Muzykantov, Vladimir R.
Published in Journal of controlled release (01.04.2022)
Published in Journal of controlled release (01.04.2022)
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Journal Article
Vascular Drug Delivery Using Carrier Red Blood Cells: Focus on RBC Surface Loading and Pharmacokinetics
Glassman, Patrick M, Villa, Carlos H, Ukidve, Anvay, Zhao, Zongmin, Smith, Paige, Mitragotri, Samir, Russell, Alan J, Brenner, Jacob S, Muzykantov, Vladimir R
Published in Pharmaceutics (09.05.2020)
Published in Pharmaceutics (09.05.2020)
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Journal Article
Targeting of nanoparticles to the cerebral vasculature after traumatic brain injury
Omo-Lamai, Serena, Nong, Jia, Savalia, Krupa, Kelley, Brian J, Wu, Jichuan, Esteves-Reyes, Sahily, Chase, Liam S, Muzykantov, Vladimir R, Marcos-Contreras, Oscar A, Dollé, Jean-Pierre, Smith, Douglas H, Brenner, Jacob S
Published in PloS one (10.06.2024)
Published in PloS one (10.06.2024)
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Journal Article
Protocol for the MicroRESUS study: The impact of circulatory shock and resuscitation on microcirculatory function and mitochondrial respiration after cardiovascular surgery
Greenwood, John C, Talebi, Fatima M, Jang, David H, Spelde, Audrey E, Kilbaugh, Todd J, Shofer, Frances S, Acker, Michael A, Augoustides, John G. T, Bakker, Jan, Meyer, Nuala J, Brenner, Jacob S, Muzykantov, Vladimir R, Abella, Benjamin S
Published in PloS one (26.08.2022)
Published in PloS one (26.08.2022)
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Journal Article
Topical nitroglycerin to detect reversible microcirculatory dysfunction in patients with circulatory shock after cardiovascular surgery: an observational study
Greenwood, John C., Talebi, Fatima M., Jang, David H., Spelde, Audrey E., Tonna, Joseph E., Gutsche, Jacob T., Horak, Jiri, Acker, Michael A., Kilbaugh, Todd J., Shofer, Frances S., Augoustides, John G. T., Bakker, Jan, Brenner, Jacob S., Muzykantov, Vladimir R., Abella, Benjamin S.
Published in Scientific reports (10.09.2022)
Published in Scientific reports (10.09.2022)
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Journal Article
Using selective lung injury to improve murine models of spatially heterogeneous lung diseases
Paris, Andrew J, Guo, Lei, Dai, Ning, Katzen, Jeremy B, Patel, Priyal N, Worthen, G Scott, Brenner, Jacob S
Published in PloS one (03.04.2019)
Published in PloS one (03.04.2019)
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Journal Article
Nanoparticle-Induced Augmentation of Neutrophils' Phagocytosis of Bacteria
Rubey, Kathryn M, Mukhitov, Alexander R, Nong, Jia, Wu, Jichuan, Krymskaya, Vera P, Myerson, Jacob W, Worthen, G Scott, Brenner, Jacob S
Published in Frontiers in pharmacology (04.07.2022)
Published in Frontiers in pharmacology (04.07.2022)
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Journal Article
Mechanisms by Which Liposomes Improve Inhaled Drug Delivery for Alveolar Diseases
Ferguson, Laura T., Ma, Xiaonan, Myerson, Jacob W., Wu, Jichuan, Glassman, Patrick M., Zamora, Marco E., Hood, Elizabeth D., Zaleski, Michael, Shen, Mengwen, Essien, Eno-Obong, Shuvaev, Vladimir V., Brenner, Jacob S.
Published in Advanced NanoBiomed Research (Online) (01.03.2023)
Published in Advanced NanoBiomed Research (Online) (01.03.2023)
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Journal Article
Monoclonal antibody 2C5 specifically targets neutrophil extracellular traps
Mendes, Livia P, Rostamizadeh, Kobra, Gollomp, Kandace, Myerson, Jacob W, Marcos-Contreras, Oscar A, Zamora, Marco, Luther, Ed, Brenner, Jacob S, Filipczak, Nina, Li, Xiang, Torchilin, Vladimir P
Published in mAbs (01.01.2020)
Published in mAbs (01.01.2020)
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Journal Article
Red Blood Cell Hitchhiking: A Novel Approach for Vascular Delivery of Nanocarriers
Brenner, Jacob S, Mitragotri, Samir, Muzykantov, Vladimir R
Published in Annual review of biomedical engineering (13.07.2021)
Published in Annual review of biomedical engineering (13.07.2021)
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Journal Article
Red blood cells: The metamorphosis of a neglected carrier into the natural mothership for artificial nanocarriers
Glassman, Patrick M., Hood, Elizabeth D., Ferguson, Laura T., Zhao, Zongmin, Siegel, Don L., Mitragotri, Samir, Brenner, Jacob S., Muzykantov, Vladimir R.
Published in Advanced drug delivery reviews (01.11.2021)
Published in Advanced drug delivery reviews (01.11.2021)
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