Regorafenib plus Vincristine and Irinotecan in Pediatric Patients with Recurrent/Refractory Solid Tumors: An Innovative Therapy for Children with Cancer Study
Casanova, Michela, Bautista, Francisco, Campbell-Hewson, Quentin, Makin, Guy, Marshall, Lynley V., Verschuur, Arnauld C., Cañete Nieto, Adela, Corradini, Nadège, Ploeger, Bart A., Brennan, Barbara J., Mueller, Udo, Zebger-Gong, Hong, Chung, John W., Geoerger, Birgit
Published in Clinical cancer research (01.11.2023)
Published in Clinical cancer research (01.11.2023)
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Assessing the translational value of pre-clinical studies for clinical response rate in oncology: an exploratory investigation of 42 FDA-approved small-molecule targeted anticancer drugs
Liu, Wenying Angela, Yu, Li, Morcos, Peter N., Mercier, Francois, Brennan, Barbara J.
Published in Cancer chemotherapy and pharmacology (01.06.2020)
Published in Cancer chemotherapy and pharmacology (01.06.2020)
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Regorafenib plus nivolumab in patients with mismatch repair-proficient/microsatellite stable metastatic colorectal cancer: a single-arm, open-label, multicentre phase 2 study
Fakih, Marwan, Raghav, Kanwal Pratap Singh, Chang, David Z., Larson, Tim, Cohn, Allen L., Huyck, Timothy K., Cosgrove, David, Fiorillo, Joseph A., Tam, Rachel, D'Adamo, David, Sharma, Neelesh, Brennan, Barbara J., Wang, Ying A., Coppieters, Sabine, Zebger-Gong, Hong, Weispfenning, Anke, Seidel, Henrik, Ploeger, Bart A., Mueller, Udo, Oliveira, Carolina Soares Viana de, Paulson, Andrew Scott
Published in EClinicalMedicine (01.04.2023)
Published in EClinicalMedicine (01.04.2023)
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A pharmacokinetic/viral kinetic model to evaluate treatment of chronic HCV infection with a non-nucleoside polymerase inhibitor
Canini, Laetitia, Lemenuel-Diot, Annabelle, Brennan, Barbara J, Smith, Patrick F, Perelson, Alan S
Published in Antiviral therapy (01.01.2018)
Published in Antiviral therapy (01.01.2018)
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Journal Article
Effect of peginterferon alfa‐2a (40KD) on cytochrome P450 isoenzyme activity
Brennan, Barbara J., Xu, Zhi‐Xin, Grippo, Joseph F.
Published in British journal of clinical pharmacology (01.02.2013)
Published in British journal of clinical pharmacology (01.02.2013)
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Journal Article
Characterization of the Transmembrane Transport and Absolute Bioavailability of the HCV Protease Inhibitor Danoprevir
Brennan, Barbara J., Poirier, Agnès, Moreira, Sebastian, Morcos, Peter N., Goelzer, Petra, Portmann, Renée, Asthappan, Jiney, Funk, Christoph, Smith, Patrick F.
Published in Clinical pharmacokinetics (01.05.2015)
Published in Clinical pharmacokinetics (01.05.2015)
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Efficacy and Safety of Danoprevir-Ritonavir plus Peginterferon Alfa-2a–Ribavirin in Hepatitis C Virus Genotype 1 Prior Null Responders
GANE, Edward J, ROUZIER, Régine, KULKARNI, Rohit, YING ZHANG, SMITH, Patrick, YETZER, Ellen S, SHULMAN, Nancy S, WIERCINSKA-DRAPALO, Alicja, LARREY, Dominique G, MORCOS, Peter N, BRENNAN, Barbara J, LE POGAM, Sophie, NAJERA, Isabel, PETRIC, Rosemary, TRAN, Jonathan Q
Published in Antimicrobial Agents and Chemotherapy (01.02.2014)
Published in Antimicrobial Agents and Chemotherapy (01.02.2014)
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Use of an integrated modelling and simulation approach to develop a simplified peginterferon alfa‐2a dosing regimen for children with hepatitis C
Brennan, Barbara J., Lemenuel‐Diot, Annabelle, Snoeck, Eric, McKenna, Michael, Solsky, Jonathan, Wat, Cynthia, Mallalieu, Navita L.
Published in British journal of clinical pharmacology (01.04.2016)
Published in British journal of clinical pharmacology (01.04.2016)
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Safety, Tolerability, and Pharmacokinetics of Intravenous Oseltamivir: Single- and Multiple-Dose Phase I Studies with Healthy Volunteers
BRENNAN, Barbara J, DAVIES, Brian, CIRRINCIONE-DALL, Georgina, MORCOS, Peter N, BERYOZKINA, Anna, CHAPPEY, Colombe, ACEVES BALDO, Pau, LENNON-CHRIMES, Sian, RAYNER, Craig R
Published in Antimicrobial Agents and Chemotherapy (01.09.2012)
Published in Antimicrobial Agents and Chemotherapy (01.09.2012)
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A randomised study of the effect of danoprevir/ritonavir or ritonavir on substrates of cytochrome P450 (CYP) 3A and 2C9 in chronic hepatitis C patients using a drug cocktail
Morcos, Peter N., Chang, Linda, Kulkarni, Rohit, Giraudon, Mylene, Shulman, Nancy, Brennan, Barbara J., Smith, Patrick F., Tran, Jonathan Q.
Published in European journal of clinical pharmacology (01.11.2013)
Published in European journal of clinical pharmacology (01.11.2013)
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Journal Article
Pharmacokinetics of a Three-Way Drug Interaction Between Danoprevir, Ritonavir and the Organic Anion Transporting Polypeptide (OATP) Inhibitor Ciclosporin
Brennan, Barbara J., Moreira, Sebastian A., Morcos, Peter N., Navarro, Mercidita T., Asthappan, Jiney, Goelzer, Petra, Weigl, Paul, Smith, Patrick F.
Published in Clinical pharmacokinetics (01.09.2013)
Published in Clinical pharmacokinetics (01.09.2013)
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Ritonavir-boosted danoprevir plus peginterferon alfa-2a and ribavirin in Asian chronic hepatitis C patients with or without cirrhosis
Kao, Jia-Horng, Tung, Shui-Yi, Lee, Younjae, Thongsawat, Satawat, Tanwandee, Tawesak, Sheen, I.-Shyan, Wu, Jinzi J., Li, Hui, Brennan, Barbara J., Zhou, Julian, Le Pogam, Sophie, Najera, Isabel, Thommes, James A., Hill, George
Published in Journal of gastroenterology and hepatology (01.10.2016)
Published in Journal of gastroenterology and hepatology (01.10.2016)
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Journal Article
Oval Cell Numbers in Human Chronic Liver Diseases Are Directly Related to Disease Severity
Lowes, Kym N., Brennan, Barbara A., Yeoh, George C., Olynyk, John K.
Published in The American journal of pathology (01.02.1999)
Published in The American journal of pathology (01.02.1999)
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Population pharmacokinetic analysis of oseltamivir and oseltamivir carboxylate following intravenous and oral administration to patients with and without renal impairment
Gibiansky, Leonid, Giraudon, Mylène, Rayner, Craig R., Brennan, Barbara J., Subramoney, Vishak, Robson, Richard, Kamal, Mohamed A.
Published in Journal of pharmacokinetics and pharmacodynamics (01.06.2015)
Published in Journal of pharmacokinetics and pharmacodynamics (01.06.2015)
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Journal Article
Evaluation of the Absolute Bioavailability of Pegylated Interferon Alfa-2a After Subcutaneous Administration to Healthy Male Volunteers: An Open-Label, Randomized, Parallel-Group Study
Brennan, Barbara J., PharmD, Xu, Zhi-Xin, MD, PhD, Grippo, Joseph F., PhD
Published in Clinical therapeutics (01.09.2012)
Published in Clinical therapeutics (01.09.2012)
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Journal Article
Effect of meal and antisecretory agents on the pharmacokinetics of danoprevir/ritonavir in healthy volunteers
Morcos, Peter N, Moreira, Sebastian A, Navarro, Mercidita T, Bech, Núria, Quatkemeyer, Amanda, Smith, Patrick F, Brennan, Barbara J
Published in Journal of pharmacy and pharmacology (01.01.2014)
Published in Journal of pharmacy and pharmacology (01.01.2014)
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Effect of ritonavir-boosted danoprevir, a potent hepatitis C virus protease inhibitor, on the pharmacokinetics of methadone in healthy subjects undergoing methadone maintenance therapy
Moreira, Sebastian A, Morcos, Peter N, Navarro, Mercidita T, Bech, Nuria, Smith, Patrick F, Brennan, Barbara J
Published in Pharmacotherapy (01.03.2014)
Published in Pharmacotherapy (01.03.2014)
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Journal Article
Induction dosing of peginterferon alfa-2a (40 KD) and/or high-dose ribavirin in genotype 1 CHC patients with difficult-to-treat characteristics: pharmacokinetic and viral kinetic (PK/VK) assessment from PROGRESS
Morcos, Peter N, Leong, Ruby, Thommes, James A, DePamphilis, Jean, Grippo, Joseph F, Brennan, Barbara J
Published in Hepato-gastroenterology (01.01.2015)
Published in Hepato-gastroenterology (01.01.2015)
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Journal Article
Value of cytology in the intraoperative assessment of ovarian tumors: a review of 402 cases and comparison with frozen section diagnosis
Stewart, Colin J R, Brennan, Barbara A, Koay, Eleanor, Naran, Anup, Ruba, Sukeerat
Published in Cancer cytopathology (25.06.2010)
Published in Cancer cytopathology (25.06.2010)
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Journal Article
Ritonavir-boosted danoprevir-based regimens in treatment-naive and prior null responders with HCV genotype 1 or 4 and compensated cirrhosis
Gane, Edward J., Rouzier, Régine, Hassanein, Tarek, Stedman, Catherine A., Mazur, Wlodzimierz, Kupcova, Viera, Le Pogam, Sophie, Eng, Simon, Voulgari, Athina, Morcos, Peter N., Brennan, Barbara J., Scalori, Astrid, Thommes, James
Published in Hepatology international (01.05.2016)
Published in Hepatology international (01.05.2016)
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