The GDF15-GFRAL Pathway in Health and Metabolic Disease: Friend or Foe?
Breit, Samuel N, Brown, David A, Tsai, Vicky Wang-Wei
Published in Annual review of physiology (10.02.2021)
Published in Annual review of physiology (10.02.2021)
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Macrophage inhibitory cytokine 1 (MIC-1/GDF15) decreases food intake, body weight and improves glucose tolerance in mice on normal & obesogenic diets
Macia, Laurence, Tsai, Vicky Wang-Wei, Nguyen, Amy D, Johnen, Heiko, Kuffner, Tamara, Shi, Yan-Chuan, Lin, Shu, Herzog, Herbert, Brown, David A, Breit, Samuel N, Sainsbury, Amanda
Published in PloS one (13.04.2012)
Published in PloS one (13.04.2012)
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Associations of serum short-chain fatty acids with circulating immune cells and serum biomarkers in patients with multiple sclerosis
Trend, Stephanie, Leffler, Jonatan, Jones, Anderson P., Cha, Lilian, Gorman, Shelley, Brown, David A., Breit, Samuel N., Kermode, Allan G., French, Martyn A., Ward, Natalie C., Hart, Prue H.
Published in Scientific reports (04.03.2021)
Published in Scientific reports (04.03.2021)
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Immune cell trafficking from the brain maintains CNS immune tolerance
Mohammad, Mohammad G, Tsai, Vicky W W, Ruitenberg, Marc J, Hassanpour, Masoud, Li, Hui, Hart, Prue H, Breit, Samuel N, Sawchenko, Paul E, Brown, David A
Published in The Journal of clinical investigation (01.03.2014)
Published in The Journal of clinical investigation (01.03.2014)
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The anorectic actions of the TGFβ cytokine MIC-1/GDF15 require an intact brainstem area postrema and nucleus of the solitary tract
Tsai, Vicky Wang-Wei, Manandhar, Rakesh, Jørgensen, Sebastian Beck, Lee-Ng, Ka Ki Michelle, Zhang, Hong Ping, Marquis, Christopher Peter, Jiang, Lele, Husaini, Yasmin, Lin, Shu, Sainsbury, Amanda, Sawchenko, Paul E, Brown, David A, Breit, Samuel N
Published in PloS one (27.06.2014)
Published in PloS one (27.06.2014)
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Growth differentiation factor-15 slows the growth of murine prostate cancer by stimulating tumor immunity
Husaini, Yasmin, Tsai, Vicky Wang-Wei, Manandhar, Rakesh, Zhang, Hong Ping, Lee-Ng, Ka Ki Michelle, Lebhar, Hélène, Marquis, Christopher P, Brown, David A, Breit, Samuel N
Published in PloS one (05.06.2020)
Published in PloS one (05.06.2020)
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GDF-15 Contributes to Proliferation and Immune Escape of Malignant Gliomas
ROTH, Patrick, JUNKER, Markus, TRITSCHLER, Isabel, MITTELBRONN, Michel, DOMBROWSKI, Yvonne, BREIT, Samuel N, TABATABAI, Ghazaleh, WICK, Wolfgang, WELLER, Michael, WISCHHUSEN, Jörg
Published in Clinical cancer research (01.08.2010)
Published in Clinical cancer research (01.08.2010)
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Macrophage inhibitory cytokine-1 (MIC-1/GDF15) slows cancer development but increases metastases in TRAMP prostate cancer prone mice
Husaini, Yasmin, Qiu, Min Ru, Lockwood, Glen P, Luo, Xu Wei, Shang, Ping, Kuffner, Tamara, Tsai, Vicky Wang-Wei, Jiang, Lele, Russell, Pamela J, Brown, David A, Breit, Samuel N
Published in PloS one (27.08.2012)
Published in PloS one (27.08.2012)
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The enigma of the CLIC proteins: Ion channels, redox proteins, enzymes, scaffolding proteins?
Littler, Dene R., Harrop, Stephen J., Goodchild, Sophia C., Phang, Juanita M., Mynott, Andrew V., Jiang, Lele, Valenzuela, Stella M., Mazzanti, Michele, Brown, Louise J., Breit, Samuel N., Curmi, Paul M.G.
Published in FEBS letters (17.05.2010)
Published in FEBS letters (17.05.2010)
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Macrophage inhibitory cytokine‐1 (MIC‐1/GDF15): a new marker of all‐cause mortality
Wiklund, Fredrik E., Bennet, Anna M., Magnusson, Patrik K. E., Eriksson, Ulrika K., Lindmark, Fredrik, Wu, Liyun, Yaghoutyfam, Nasreen, Marquis, Christopher P., Stattin, Pär, Pedersen, Nancy L., Adami, Hans‐Olov, Grönberg, Henrik, Breit, Samuel N., Brown, David A.
Published in Aging cell (01.12.2010)
Published in Aging cell (01.12.2010)
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Serum Levels of Human MIC-1/GDF15 Vary in a Diurnal Pattern, Do Not Display a Profile Suggestive of a Satiety Factor and Are Related to BMI
Tsai, Vicky Wang-Wei, Macia, Laurence, Feinle-Bisset, Christine, Manandhar, Rakesh, Astrup, Arne, Raben, Anne, Lorenzen, Janne Kunchel, Schmidt, Peter T, Wiklund, Fredrik, Pedersen, Nancy L, Campbell, Lesley, Kriketos, Adamandia, Xu, Aimin, Pengcheng, Zhou, Jia, Weiping, Curmi, Paul M G, Angstmann, Christopher N, Lee-Ng, Ka Ki Michelle, Zhang, Hong Ping, Marquis, Christopher P, Husaini, Yasmin, Beglinger, Christoph, Lin, Shu, Herzog, Herbert, Brown, David A, Sainsbury, Amanda, Breit, Samuel N
Published in PloS one (24.07.2015)
Published in PloS one (24.07.2015)
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Role of macrophage inhibitory cytokine-1 in tumorigenesis and diagnosis of cancer
BAUSKIN, Asne R, BROWN, David A, KUFFNER, Tamara, JOHNEN, Heiko, LUO, X. Wei, HUNTER, Mark, BREIT, Samuel N
Published in Cancer research (Chicago, Ill.) (15.05.2006)
Published in Cancer research (Chicago, Ill.) (15.05.2006)
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Macrophage inhibitory cytokine-1 (MIC-1/GDF15) gene deletion promotes cancer growth in TRAMP prostate cancer prone mice
Husaini, Yasmin, Lockwood, Glen P, Nguyen, Trung V, Tsai, Vicky Wang-Wei, Mohammad, Mohammad G, Russell, Pamela J, Brown, David A, Breit, Samuel N
Published in PloS one (19.02.2015)
Published in PloS one (19.02.2015)
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CLIC proteins, ezrin, radixin, moesin and the coupling of membranes to the actin cytoskeleton: A smoking gun?
Jiang, Lele, Phang, Juanita M., Yu, Jiang, Harrop, Stephen J., Sokolova, Anna V., Duff, Anthony P., Wilk, Krystyna E., Alkhamici, Heba, Breit, Samuel N., Valenzuela, Stella M., Brown, Louise J., Curmi, Paul M.G.
Published in Biochimica et biophysica acta (01.02.2014)
Published in Biochimica et biophysica acta (01.02.2014)
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Macrophage Inhibitory Cytokine 1: A New Prognostic Marker in Prostate Cancer
Brown, David A, Lindmark, Fredrik, Stattin, Pär, Bälter, Katarina, Adami, Hans-Olov, Zheng, Sigun L, Xu, Jianfeng, Isaacs, William B, Grönberg, Henrik, Breit, Samuel N, Wiklund, Fredrik E
Published in Clinical cancer research (01.11.2009)
Published in Clinical cancer research (01.11.2009)
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Identification of Candidate Biomarkers of Therapeutic Response to Docetaxel by Proteomic Profiling
LIANGLI ZHAO, LEE, Brian Y, SUTHERLAND, Robert L, HENSHALL, Susan M, HORVATH, Lisa G, BROWN, David A, MOLLOY, Mark P, MARX, Gavin M, PAVLAKIS, Nick, BOYER, Michael J, STOCKLER, Martin R, KAPLAN, Warren, BREIT, Samuel N
Published in Cancer research (Chicago, Ill.) (01.10.2009)
Published in Cancer research (Chicago, Ill.) (01.10.2009)
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First Behavioural Characterisation of a Knockout Mouse Model for the Transforming Growth Factor (TGF)-β Superfamily Cytokine, MIC-1/GDF15
Low, Jac Kee, Ambikairajah, Ananthan, Shang, Kani, Brown, David A, Tsai, Vicky W W, Breit, Samuel N, Karl, Tim
Published in PloS one (01.01.2017)
Published in PloS one (01.01.2017)
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Serum Markers in Patients with Resectable Pancreatic Adenocarcinoma: Macrophage Inhibitory Cytokine 1 versus CA19-9
KOOPMANN, Jens, ROSENZWEIG, C. Nicole White, ZHEN ZHANG, CANTO, Marcia I, BROWN, David A, HUNTER, Mark, YEO, Charles, CHAN, Daniel W, BREIT, Samuel N, GOGGINS, Michael
Published in Clinical cancer research (15.01.2006)
Published in Clinical cancer research (15.01.2006)
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