GDF-15 Neutralization Alleviates Platinum-Based Chemotherapy-Induced Emesis, Anorexia, and Weight Loss in Mice and Nonhuman Primates
Breen, Danna M., Kim, Hanna, Bennett, Donald, Calle, Roberto A., Collins, Susie, Esquejo, Ryan M., He, Tao, Joaquim, Stephanie, Joyce, Alison, Lambert, Matthew, Lin, Laura, Pettersen, Betty, Qiao, Shuxi, Rossulek, Michelle, Weber, Gregory, Wu, Zhidan, Zhang, Bei B., Birnbaum, Morris J.
Published in Cell metabolism (01.12.2020)
Published in Cell metabolism (01.12.2020)
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Resveratrol activates duodenal Sirt1 to reverse insulin resistance in rats through a neuronal network
Côté, Clémence D, Rasmussen, Brittany A, Duca, Frank A, Zadeh-Tahmasebi, Melika, Baur, Joseph A, Daljeet, Mira, Breen, Danna M, Filippi, Beatrice M, Lam, Tony K T
Published in Nature medicine (01.05.2015)
Published in Nature medicine (01.05.2015)
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Activation of the hypothalamic–pituitary–adrenal axis by exogenous and endogenous GDF15
Cimino, Irene, Kim, Hanna, Tung, Y. C. Loraine, Pedersen, Kent, Rimmington, Debra, Tadross, John A., Kohnke, Sara N., Neves-Costa, Ana, Barros, André, Joaquim, Stephanie, Bennett, Don, Melvin, Audrey, Lockhart, Samuel M., Rostron, Anthony J., Scott, Jonathan, Liu, Hui, Burling, Keith, Barker, Peter, Clatworthy, Menna R., Lee, E-Chiang, Simpson, A. John, Yeo, Giles S. H., Moita, Luís F., Bence, Kendra K., Jørgensen, Sebastian Beck, Coll, Anthony P., Breen, Danna M., O’Rahilly, Stephen
Published in Proceedings of the National Academy of Sciences - PNAS (06.07.2021)
Published in Proceedings of the National Academy of Sciences - PNAS (06.07.2021)
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Phase 2 study of the efficacy and safety of ponsegromab in patients with cancer cachexia: PROACC‐1 study design
Groarke, John D., Crawford, Jeffrey, Collins, Susie M., Lubaczewski, Shannon L., Breen, Danna M., Harrington, Magdalena A., Jacobs, Ira, Qiu, Ruolun, Revkin, James, Rossulek, Michelle I., Saxena, Aditi R.
Published in Journal of cachexia, sarcopenia and muscle (01.06.2024)
Published in Journal of cachexia, sarcopenia and muscle (01.06.2024)
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Nutrient-Sensing Mechanisms in the Gut as Therapeutic Targets for Diabetes
BREEN, Danna M, RASMUSSEN, Brittany A, COTE, Clémence D, MARGARET JACKSON, V, LAM, Tony K. T
Published in Diabetes (New York, N.Y.) (01.09.2013)
Published in Diabetes (New York, N.Y.) (01.09.2013)
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Resveratrol Inhibits Neointimal Growth after Arterial Injury in High-Fat-Fed Rodents: The Roles of SIRT1 and AMPK
Guo, June, Pereira, Troy J., Mori, Yusaku, Gonzalez Medina, Marel, Breen, Danna M., Dalvi, Prasad S., Zhang, Hangjun, McCole, Declan F., McBurney, Michael W., Heximer, Scott P., Tsiani, Evangelia L., Dolinsky, Vernon W., Giacca, Adria
Published in Journal of vascular research (01.11.2020)
Published in Journal of vascular research (01.11.2020)
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Pharmacological inhibition of IRAK4 kinase activity does not prevent cachexia in mice with pancreatic cancer
Qiao, Shuxi, LaViolette, Brianna, Paulhus, Brianna LaCarubba, Li, Xiangping, Litchfield, John, Li, Zhenhong, Stansfield, John C., Gieseck, Richard L., Zhang, Bei B., Breen, Danna M.
Published in JCSM rapid communications (01.07.2023)
Published in JCSM rapid communications (01.07.2023)
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Jejunal Leptin-PI3K Signaling Lowers Glucose Production
Rasmussen, Brittany A., Breen, Danna M., Duca, Frank A., Côté, Clémence D., Zadeh-Tahmasebi, Melika, Filippi, Beatrice M., Lam, Tony K.T.
Published in Cell metabolism (07.01.2014)
Published in Cell metabolism (07.01.2014)
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In vivo effects of polyunsaturated, monounsaturated, and saturated fatty acids on hepatic and peripheral insulin sensitivity
Pereira, Sandra, Breen, Danna M, Naassan, Anthony E, Wang, Penny Y.T, Uchino, Hiroshi, Fantus, I. George, Carpentier, André C, Gutierrez-Juarez, Roger, Brindley, David N, Lam, Tony K.T, Giacca, Adria
Published in Metabolism, clinical and experimental (01.02.2015)
Published in Metabolism, clinical and experimental (01.02.2015)
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Growth differentiation factor 15 neutralization does not impact anorexia or survival in lipopolysaccharide-induced inflammation
Breen, Danna M., Jagarlapudi, Srinath, Patel, Anita, Zou, Chang, Joaquim, Stephanie, Li, Xiangping, Kang, Liya, Pang, Jincheng, Hales, Katherine, Ziso-Qejvanaj, Enida, Vera, Nicholas B., Bennett, Donald, He, Tao, Lambert, Matthew, Kelleher, Kerry, Wu, Zhidan, Zhang, Bei B., Lin, Laura, Seeley, Randy J., Bezy, Olivier
Published in iScience (25.06.2021)
Published in iScience (25.06.2021)
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Insulin Increases Reendothelialization and Inhibits Cell Migration and Neointimal Growth After Arterial Injury
BREEN, Danna M, CHAN, Kalam K, BENDECK, Michelle P, GIACCA, Adria, DHALIWALL, Jiwanjeet K, WARD, Michael R, AL KOUDSI, Nael, LAM, Loretta, DE SOUZA, Melissa, GHANIM, Husam, DANDONA, Paresh, STEWART, Duncan J
Published in Arteriosclerosis, thrombosis, and vascular biology (01.07.2009)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.07.2009)
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Jejunal nutrient sensing is required for duodenal-jejunal bypass surgery to rapidly lower glucose concentrations in uncontrolled diabetes
Breen, Danna M, Rasmussen, Brittany A, Kokorovic, Andrea, Wang, Rennian, Cheung, Grace W C, Lam, Tony K T
Published in Nature medicine (01.06.2012)
Published in Nature medicine (01.06.2012)
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Latest approaches for the treatment of obesity
Jackson, V Margaret, Breen, Danna M, Fortin, Jean-Philippe, Liou, Alice, Kuzmiski, J Brent, Loomis, A Katrina, Rives, Marie-Laure, Shah, Bhavik, Carpino, Philip A
Published in Expert opinion on drug discovery (03.08.2015)
Published in Expert opinion on drug discovery (03.08.2015)
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Frequency of weight and body composition increases in advanced non-small cell lung cancer patients during first line therapy
Bonomi, Philip, Moudgalya, Hita, Gomez, Sandra L, Shah, Palmi, Basu, Sanjib, Batus, Marta, Martinka, Levi B, Abdelkader, Ahmed, Tzameli, Iphigenia, Cobain, Sonia, Collins, Susie, Keliher, Edmund J, Breen, Danna M, Calle, Roberto A, Fidler, Mary Jo, Borgia, Jeffrey A
Published in Journal of cachexia, sarcopenia and muscle (17.09.2024)
Published in Journal of cachexia, sarcopenia and muscle (17.09.2024)
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Characterization of cachexia in the human fibrosarcoma HT‐1080 mouse tumour model
Bernardo, Barbara, Joaquim, Stephanie, Garren, Jeonifer, Boucher, Magalie, Houle, Christopher, LaCarubba, Brianna, Qiao, Shuxi, Wu, Zhidan, Esquejo, Ryan M., Peloquin, Matthew, Kim, Hanna, Breen, Danna M.
Published in Journal of cachexia, sarcopenia and muscle (01.12.2020)
Published in Journal of cachexia, sarcopenia and muscle (01.12.2020)
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Resveratrol prevents insulin resistance caused by short-term elevation of free fatty acids in vivo
Pereira, Sandra, Park, Edward, Moore, Jessy, Faubert, Brandon, Breen, Danna M, Oprescu, Andrei I, Nahle, Ashraf, Kwan, Denise, Giacca, Adria, Tsiani, Evangelia
Published in Applied physiology, nutrition, and metabolism (01.11.2015)
Published in Applied physiology, nutrition, and metabolism (01.11.2015)
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High-dose metformin (420 mg/kg daily p.o.) increases insulin sensitivity but does not affect neointimal thickness in the rat carotid balloon injury model of restenosis
Guo, June, Pereira, Troy J, Dalvi, Prasad, Yeung, Lucy Shu Nga, Swain, Nathan, Breen, Danna M, Lam, Loretta, Dolinsky, Vernon W, Giacca, Adria
Published in Metabolism, clinical and experimental (01.03.2017)
Published in Metabolism, clinical and experimental (01.03.2017)
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The effect of insulin to decrease neointimal growth after arterial injury is endothelial nitric oxide synthase-dependent
Guo, June, Breen, Danna M, Pereira, Troy J, Dalvi, Prasad S, Zhang, Hangjun, Mori, Yusaku, Ghanim, Husam, Tumiati, Laura, Fantus, I. George, Bendeck, Michelle P, Dandona, Paresh, Rao, Vivek, Dolinsky, Vernon W, Heximer, Scott P, Giacca, Adria
Published in Atherosclerosis (01.07.2015)
Published in Atherosclerosis (01.07.2015)
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