Wild-type phosphoribosylpyrophosphate synthase (PRS) from Mycobacterium tuberculosis: a bacterial class II PRS?
Breda, Ardala, Martinelli, Leonardo K B, Bizarro, Cristiano V, Rosado, Leonardo A, Borges, Caroline B, Santos, Diógenes S, Basso, Luiz A
Published in PloS one (20.06.2012)
Published in PloS one (20.06.2012)
Get full text
Journal Article
Recombinant Escherichia coli GMP reductase: kinetic, catalytic and chemical mechanisms, and thermodynamics of enzyme-ligand binary complex formation
Martinelli, Leonardo Krás Borges, Ducati, Rodrigo Gay, Rosado, Leonardo Astolfi, Breda, Ardala, Selbach, Bruna Pelegrim, Santos, Diógenes Santiago, Basso, Luiz Augusto
Published in Molecular bioSystems (01.01.2011)
Published in Molecular bioSystems (01.01.2011)
Get full text
Journal Article
Molecular, kinetic and thermodynamic characterization of Mycobacterium tuberculosisorotate phosphoribosyltransferase
Breda, Ardala, Rosado, Leonardo Astolfi, Lorenzini, Daniel Macedo, Basso, Luiz Augusto, Santos, Diógenes Santiago
Published in Molecular bioSystems (2012)
Published in Molecular bioSystems (2012)
Get full text
Journal Article
Essential but Not Vulnerable: Indazole Sulfonamides Targeting Inosine Monophosphate Dehydrogenase as Potential Leads against Mycobacterium tuberculosis
Park, Yumi, Pacitto, Angela, Bayliss, Tracy, Cleghorn, Laura A. T, Wang, Zhe, Hartman, Travis, Arora, Kriti, Ioerger, Thomas R, Sacchettini, Jim, Rizzi, Menico, Donini, Stefano, Blundell, Tom L, Ascher, David B, Rhee, Kyu, Breda, Ardala, Zhou, Nian, Dartois, Veronique, Jonnala, Surendranadha Reddy, Via, Laura E, Mizrahi, Valerie, Epemolu, Ola, Stojanovski, Laste, Simeons, Fred, Osuna-Cabello, Maria, Ellis, Lucy, MacKenzie, Claire J, Smith, Alasdair R. C, Davis, Susan H, Murugesan, Dinakaran, Buchanan, Kirsteen I, Turner, Penelope A, Huggett, Margaret, Zuccotto, Fabio, Rebollo-Lopez, Maria Jose, Lafuente-Monasterio, Maria Jose, Sanz, Olalla, Diaz, Gracia Santos, Lelièvre, Joël, Ballell, Lluis, Selenski, Carolyn, Axtman, Matthew, Ghidelli-Disse, Sonja, Pflaumer, Hannah, Bösche, Markus, Drewes, Gerard, Freiberg, Gail M, Kurnick, Matthew D, Srikumaran, Myron, Kempf, Dale J, Green, Simon R, Ray, Peter C, Read, Kevin, Wyatt, Paul, Barry, Clifton E, Boshoff, Helena I
Published in ACS infectious diseases (13.01.2017)
Published in ACS infectious diseases (13.01.2017)
Get full text
Journal Article
Structure, activity, and inhibition of the Carboxyltransferase β-subunit of acetyl coenzyme A carboxylase (AccD6) from Mycobacterium tuberculosis
Reddy, Manchi C M, Breda, Ardala, Bruning, John B, Sherekar, Mukul, Valluru, Spandana, Thurman, Cory, Ehrenfeld, Hannah, Sacchettini, James C
Published in Antimicrobial agents and chemotherapy (01.10.2014)
Published in Antimicrobial agents and chemotherapy (01.10.2014)
Get full text
Journal Article
Pyrimidin-2(1H)-ones based inhibitors of Mycobacterium tuberculosis orotate phosphoribosyltransferase
Breda, Ardala, Machado, Pablo, Rosado, Leonardo Astolfi, Souto, André Arigony, Santos, Diógenes Santiago, Basso, Luiz Augusto
Published in European journal of medicinal chemistry (01.08.2012)
Published in European journal of medicinal chemistry (01.08.2012)
Get full text
Journal Article
Cloning and characterization of bifunctional enzyme farnesyl diphosphate/geranylgeranyl diphosphate synthase from Plasmodium falciparum
Jordão, Fabiana M, Gabriel, Heloisa B, Alves, João M P, Angeli, Claudia B, Bifano, Thaís D, Breda, Ardala, de Azevedo, Mauro F, Basso, Luiz A, Wunderlich, Gerhard, Kimura, Emilia A, Katzin, Alejandro M
Published in Malaria journal (04.06.2013)
Published in Malaria journal (04.06.2013)
Get full text
Journal Article
Molecular, kinetic and thermodynamic characterization of Mycobacterium tuberculosis orotate phosphoribosyltransferase
Breda, Ardala, Rosado, Leonardo Astolfi, Lorenzini, Daniel Macedo, Basso, Luiz Augusto, Santos, Diógenes Santiago
Published in Molecular bioSystems (01.01.2012)
Published in Molecular bioSystems (01.01.2012)
Get full text
Journal Article
Wild-Type Phosphoribosylpyrophosphate Synthase
Breda, Ardala, Martinelli, Leonardo K. B, Bizarro, Cristiano V, Rosado, Leonardo A, Borges, Caroline B, Santos, Diógenes S, Basso, Luiz A
Published in PloS one (20.06.2012)
Published in PloS one (20.06.2012)
Get full text
Journal Article
UMP kinase from Mycobacterium tuberculosis: Mode of action and allosteric interactions, and their likely role in pyrimidine metabolism regulation
Rostirolla, Diana C., Breda, Ardala, Rosado, Leonardo A., Palma, Mario S., Basso, Luiz A., Santos, Diógenes S.
Published in Archives of biochemistry and biophysics (15.01.2011)
Published in Archives of biochemistry and biophysics (15.01.2011)
Get full text
Journal Article
Molecular, kinetic and thermodynamic characterization of Mycobacterium tuberculosis orotate phosphoribosyltransferaseThis work is dedicated to the memory of late Prof. Ir. Norberto Rauch, who is an example of an enterprising dean and a tireless champion of the advancement of teaching and science in Brazil.Electronic supplementary information (ESI) available. See DOI: 10.1039/c1mb05402c
Breda, Ardala, Rosado, Leonardo Astolfi, Lorenzini, Daniel Macedo, Basso, Luiz Augusto, Santos, Digenes Santiago
Year of Publication 01.02.2012
Year of Publication 01.02.2012
Get full text
Journal Article
Molecular, kinetic, thermodynamic, and structural analyses of Mycobacterium tuberculosis hisD-encoded metal-dependent dimeric histidinol dehydrogenase (EC 1.1.1.23)
Nunes, José E S, Ducati, Rodrigo G, Breda, Ardala, Rosado, Leonardo A, de Souza, Bibiana M, Palma, Mario S, Santos, Diógenes S, Basso, Luiz A
Published in Archives of biochemistry and biophysics (15.08.2011)
Published in Archives of biochemistry and biophysics (15.08.2011)
Get full text
Journal Article
Molecular, kinetic, thermodynamic, and structural analyses of Mycobacterium tuberculosishisD-encoded metal-dependent dimeric histidinol dehydrogenase (EC 1.1.1.23)
Nunes, José E.S., Ducati, Rodrigo G., Breda, Ardala, Rosado, Leonardo A., de Souza, Bibiana M., Palma, Mario S., Santos, Diógenes S., Basso, Luiz A.
Published in Archives of biochemistry and biophysics (15.08.2011)
Published in Archives of biochemistry and biophysics (15.08.2011)
Get full text
Journal Article
Molecular, kinetic, thermodynamic, and structural analyses of Mycobacterium tuberculosis hisD-encoded metal-dependent dimeric histidinol dehydrogenase (EC 1.1.1.23)
Nunes, José E S, Ducati, Rodrigo G, Breda, Ardala, Rosado, Leonardo A, de Souza, Bibiana M, Palma, Mario S, Santos, Diógenes S, Basso, Luiz A
Published in Archives of biochemistry and biophysics (15.08.2011)
Published in Archives of biochemistry and biophysics (15.08.2011)
Get full text
Journal Article
A structural model for chorismate synthase from Mycobacterium tuberculosis in complex with coenzyme and substrate
Fernandes, Cláudia Lemelle, Breda, Ardala, Santiago Santos, Diógenes, Augusto Basso, Luiz, Osmar Norberto de Souza
Published in Computers in biology and medicine (01.02.2007)
Published in Computers in biology and medicine (01.02.2007)
Get full text
Journal Article
Bioinformatics Tools for HIV-1 Identification in Southern Brazilian States
Breda, Ardala, Fernandes, Cláudia Lemelle, de Matos Almeida, Sabrina Esteves, Franco, Heitor Moreira, Rossetti, Maria Lúcia Rosa, Rodrigues, Rosângela, Brígido, Luís Fernando, Cortez-Herrera, Elizabeth
Published in Advances in Bioinformatics and Computational Biology (2005)
Published in Advances in Bioinformatics and Computational Biology (2005)
Get full text
Book Chapter
Scheduling complex computer simulations on heterogeneous non-dedicated machines: a case study in structural bioinformatics
Netto, M.A.S., Breda, A., de Souza, O.S.
Published in CCGrid 2005. IEEE International Symposium on Cluster Computing and the Grid, 2005 (2005)
Published in CCGrid 2005. IEEE International Symposium on Cluster Computing and the Grid, 2005 (2005)
Get full text
Conference Proceeding