Pharmacological characterization of GLPG1972/S201086, a potent and selective small-molecule inhibitor of ADAMTS5
Clement-Lacroix, P., Little, C.B., Smith, M.M., Cottereaux, C., Merciris, D., Meurisse, S., Mollat, P., Touitou, R., Brebion, F., Gosmini, R., De Ceuninck, F., Botez, I., Lepescheux, L., van der Aar, E., Christophe, T., Vandervoort, N., Blanqué, R., Comas, D., Deprez, P., Amantini, D.
Published in Osteoarthritis and cartilage (01.02.2022)
Published in Osteoarthritis and cartilage (01.02.2022)
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Journal Article
OP0258 Efficacy of the highly selective adamts-5 inhibitor glpg1972 in the rat meniscectomy model
Lepescheux, L., Clement-Lacroix, P., Merciris, D., Meurisse, S., Borgonovi, M., Cottereaux, C., Mollat, P., Brebion, F., Gosmini, R., De Ceuninck, F., Botez, I., van der Aar, E., Christophe, T., Vandervoort, N., Blanqué, R., Comas, D., Deprez, P., Amantini, D.
Published in Annals of the rheumatic diseases (01.06.2018)
Published in Annals of the rheumatic diseases (01.06.2018)
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Journal Article
GLPG1972: a potent, selective, orally available adamts-5 inhibitor for the treatment of OA
Clement-Lacroix, P, Little, C, Meurisse, S, Blanqué, R, Mollat, P, Brebion, F, Gosmini, R, De Ceuninck, F, Botez, I, Lepescheux, L, van der Aar, E, Christophe, T, Vandervoort, N, Cottereaux, C, Comas, D, Deprez, P, Amantini, D
Published in Osteoarthritis and cartilage (01.04.2017)
Published in Osteoarthritis and cartilage (01.04.2017)
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Journal Article
ADAMTS-5 inhibition with the potent and highly selective inhibitor GLPG1972 results in strong disease-modifying OA drug effects in the rat meniscectomy model
Clement-Lacroix, P., Meurisse, S., Lepescheux, L., Merciris, D., Borgonovi, M., Cottereaux, C., Mollat, P., Brebion, F., Gosmini, R., De Ceuninck, F., Botez, I., Christophe, T., van der Aar, E.E., Vandervoort, N., Blanqué, R., Comas, D., Deprez, P., Amantini, D.
Published in Osteoarthritis and cartilage (01.04.2018)
Published in Osteoarthritis and cartilage (01.04.2018)
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Journal Article
OP0180 Pharmacological characterization of the ADAMTS-5 inhibitor GLPG1972: an oral anti-catabolic agent for the treatment of osteoarthritis
Clement-Lacroix, P, Little, C, Blanqué, R, Meurisse, S, Mollat, P, Brebion, F, Gosmini, R, Ceuninck, F De, Botez, I, Lepescheux, L, Aar, E van der, Christophe, T, Vandervoort, N, Cottereaux, C, Comas, D, Deprez, P, Amantini, D
Published in Annals of the rheumatic diseases (01.06.2017)
Published in Annals of the rheumatic diseases (01.06.2017)
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Journal Article
Highly Diastereoselective Conjugate Addition to Alkylidene Bis(Sulfoxides): Asymmetric Synthesis of (+)-erythro-Roccellic Acid
Brebion, Franck, Delouvrié, Bénédicte, Nájera, Francisco, Fensterbank, Louis, Malacria, Max, Vaissermann, Jacqueline
Published in Angewandte Chemie (International ed.) (10.11.2003)
Published in Angewandte Chemie (International ed.) (10.11.2003)
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Journal Article
Highly diastereoselective Michael additions onto dienyl bis-sulfoxides
Brebion, F, Goddard, JP, Fensterbank, L, Malacria, M
Published in Synthesis (Stuttgart) (02.09.2005)
Published in Synthesis (Stuttgart) (02.09.2005)
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Journal Article
1-Phosphanorbornadiene-imines and amines in enantioselective allylic C- and N-alkylation
Mercier, François, Brebion, Franck, Dupont, Romain, Mathey, François
Published in Tetrahedron: asymmetry (17.10.2003)
Published in Tetrahedron: asymmetry (17.10.2003)
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Journal Article
Enantioselective Synthesis of Thiosulfinates and of Acyclic Alkylidenemethylene Sulfide Sulfoxides
Colonna, Stefano, Pironti, Vincenza, Drabowicz, Jozef, Brebion, Franck, Fensterbank, Louis, Malacria, Max
Published in European Journal of Organic Chemistry (01.05.2005)
Published in European Journal of Organic Chemistry (01.05.2005)
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Book Review
Journal Article
A 1,1 '-ferrocenylene-bridged analogue of BIPNOR
Frison, G, Brebion, F, Dupont, R, Mercier, F, Ricard, L, Mathey, F
Published in Comptes rendus. Chimie (01.04.2002)
Published in Comptes rendus. Chimie (01.04.2002)
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