Structural basis of collagen fiber degradation by cathepsin K
Aguda, Adeleke H., Panwar, Preety, Du, Xin, Nguyen, Nham T., Brayer, Gary D., Brömme, Dieter
Published in Proceedings of the National Academy of Sciences - PNAS (09.12.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (09.12.2014)
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The amylase inhibitor montbretin A reveals a new glycosidase inhibition motif
Williams, Leslie K, Zhang, Xiaohua, Caner, Sami, Tysoe, Christina, Nguyen, Nham T, Wicki, Jacqueline, Williams, David E, Coleman, John, McNeill, John H, Yuen, Violet, Andersen, Raymond J, Withers, Stephen G, Brayer, Gary D
Published in Nature chemical biology (01.09.2015)
Published in Nature chemical biology (01.09.2015)
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Ivermectin inhibits HSP27 and potentiates efficacy of oncogene targeting in tumor models
Nappi, Lucia, Aguda, Adeleke H, Nakouzi, Nader Al, Lelj-Garolla, Barbara, Beraldi, Eliana, Lallous, Nada, Thi, Marisa, Moore, Susan, Fazli, Ladan, Battsogt, Dulguun, Stief, Sophie, Ban, Fuqiang, Nguyen, Nham T, Saxena, Neetu, Dueva, Evgenia, Zhang, Fan, Yamazaki, Takeshi, Zoubeidi, Amina, Cherkasov, Artem, Brayer, Gary D, Gleave, Martin
Published in The Journal of clinical investigation (01.02.2020)
Published in The Journal of clinical investigation (01.02.2020)
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Journal Article
Rapid Discovery of Potent and Selective Glycosidase-Inhibiting De Novo Peptides
Jongkees, Seino A.K., Caner, Sami, Tysoe, Christina, Brayer, Gary D., Withers, Stephen G., Suga, Hiroaki
Published in Cell chemical biology (16.03.2017)
Published in Cell chemical biology (16.03.2017)
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Journal Article
Luminal Substrate “Brake” on Mucosal Maltase‐glucoamylase Activity Regulates Total Rate of Starch Digestion to Glucose
Quezada‐Calvillo, Roberto, Robayo‐Torres, Claudia C, Ao, Zihua, Hamaker, Bruce R, Quaroni, Andrea, Brayer, Gary D, Sterchi, Erwin E, Baker, Susan S, Nichols, Buford L
Published in Journal of pediatric gastroenterology and nutrition (01.07.2007)
Published in Journal of pediatric gastroenterology and nutrition (01.07.2007)
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Journal Article
Potent Human α‑Amylase Inhibition by the β‑Defensin-like Protein Helianthamide
Tysoe, Christina, Williams, Leslie K, Keyzers, Robert, Nguyen, Nham T, Tarling, Chris, Wicki, Jacqueline, Goddard-Borger, Ethan D, Aguda, Adeleke H, Perry, Suzanne, Foster, Leonard J, Andersen, Raymond J, Brayer, Gary D, Withers, Stephen G
Published in ACS central science (23.03.2016)
Published in ACS central science (23.03.2016)
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Journal Article
Structure, Binding, and Activity of Syd, a SecY-interacting Protein
Dalal, Kush, Nguyen, Nham, Alami, Meriem, Tan, Jennifer, Moraes, Trevor F., Lee, Woo Cheol, Maurus, Robert, Sligar, Stephen S., Brayer, Gary D., Duong, Franck
Published in The Journal of biological chemistry (20.03.2009)
Published in The Journal of biological chemistry (20.03.2009)
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Journal Article
Sugar Ring Distortion in the Glycosyl-Enzyme Intermediate of a Family G/11 Xylanase
Sidhu, Gary, Withers, Stephen G, Nguyen, Nham T, McIntosh, Lawrence P, Ziser, Lothar, Brayer, Gary D
Published in Biochemistry (Easton) (27.04.1999)
Published in Biochemistry (Easton) (27.04.1999)
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Journal Article
Evaluation of the Significance of Starch Surface Binding Sites on Human Pancreatic α‑Amylase
Zhang, Xiaohua, Caner, Sami, Kwan, Emily, Li, Chunmin, Brayer, Gary D, Withers, Stephen G
Published in Biochemistry (Easton) (01.11.2016)
Published in Biochemistry (Easton) (01.11.2016)
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Journal Article
Two High-Resolution Crystal Structures of the Recombinant N-Lobe of Human Transferrin Reveal a Structural Change Implicated in Iron Release
MacGillivray, Ross T. A, Moore, Stanley A, Chen, Jie, Anderson, Bryan F, Baker, Heather, Luo, Yaoguang, Bewley, Maria, Smith, Clyde A, Murphy, Michael E. P, Wang, Yili, Mason, Anne B, Woodworth, Robert C, Brayer, Gary D, Baker, Edward N
Published in Biochemistry (Easton) (02.06.1998)
Published in Biochemistry (Easton) (02.06.1998)
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Journal Article
Search for Novel Human Pancreatic α-Amylase Inhibitors: High-Throughput Screening of Terrestrial and Marine Natural Product Extracts
Tarling, Chris A, Woods, Kate, Zhang, Ran, Brastianos, Harry C, Brayer, Gary D, Andersen, Raymond J, Withers, Stephen G
Published in Chembiochem : a European journal of chemical biology (15.02.2008)
Published in Chembiochem : a European journal of chemical biology (15.02.2008)
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Journal Article
Glucosyl epi‐cyclophellitol allows mechanism‐based inactivation and structural analysis of human pancreatic α‐amylase
Caner, Sami, Zhang, Xiaohua, Jiang, Jianbing, Chen, Hong‐Ming, Nguyen, Nham T., Overkleeft, Hermen, Brayer, Gary D., Withers, Stephen G.
Published in FEBS letters (01.04.2016)
Published in FEBS letters (01.04.2016)
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Journal Article
Folding Then Binding vs Folding Through Binding in Macrocyclic Peptide Inhibitors of Human Pancreatic α‑Amylase
Goldbach, Leander, Vermeulen, Bram J. A, Caner, Sami, Liu, Minglong, Tysoe, Christina, van Gijzel, Lieke, Yoshisada, Ryoji, Trellet, Mikael, van Ingen, Hugo, Brayer, Gary D, Bonvin, Alexandre M. J. J, Jongkees, Seino A. K
Published in ACS chemical biology (16.08.2019)
Published in ACS chemical biology (16.08.2019)
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Probing the Roles of Key Residues in the Unique Regulatory NADH Binding Site of Type II Citrate Synthase of Escherichia coli
Stokell, David J., Donald, Lynda J., Maurus, Robert, Nguyen, Nham T., Sadler, Gillian, Choudhary, Kajal, Hultin, Philip G., Brayer, Gary D., Duckworth, Harry W.
Published in The Journal of biological chemistry (12.09.2003)
Published in The Journal of biological chemistry (12.09.2003)
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