Targeting protein phosphatase PP2A for cancer therapy: development of allosteric pharmaceutical agents
Brautigan, David L, Farrington, Caroline, Narla, Goutham
Published in Clinical science (1979) (16.07.2021)
Published in Clinical science (1979) (16.07.2021)
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A non-canonical, interferon-independent signaling activity of cGAMP triggers DNA damage response signaling
Banerjee, Daipayan, Langberg, Kurt, Abbas, Salar, Odermatt, Eric, Yerramothu, Praveen, Volaric, Martin, Reidenbach, Matthew A., Krentz, Kathy J., Rubinstein, C. Dustin, Brautigan, David L., Abbas, Tarek, Gelfand, Bradley D., Ambati, Jayakrishna, Kerur, Nagaraj
Published in Nature communications (27.10.2021)
Published in Nature communications (27.10.2021)
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Modulation of Primary Cilia by Alvocidib Inhibition of CILK1
Wang, Elena X., Turner, Jacob S., Brautigan, David L., Fu, Zheng
Published in International journal of molecular sciences (01.08.2022)
Published in International journal of molecular sciences (01.08.2022)
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Journal Article
Midzone activation of aurora B in anaphase produces an intracellular phosphorylation gradient
Fuller, Brian G, Brautigan, David L, Kapoor, Tarun M, Rosasco-Nitcher, Sara, Le, Kim V, Tobelmann, Page, Stukenberg, P. Todd, Lampson, Michael A, Foley, Emily A
Published in Nature (19.06.2008)
Published in Nature (19.06.2008)
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Phosphosite T674A mutation in kinesin family member 3A fails to reproduce tissue and ciliary defects characteristic of CILK1 loss of function
Gailey, Casey D., Wang, Eric J., Jin, Li, Ahmadi, Sean, Brautigan, David L., Li, Xudong, Xu, Wenhao, Scott, Michael M., Fu, Zheng
Published in Developmental dynamics (01.02.2021)
Published in Developmental dynamics (01.02.2021)
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Journal Article
Activation of DNA-PK by ionizing radiation is mediated by protein phosphatase 6
Mi, Jun, Dziegielewski, Jaroslaw, Bolesta, Elzbieta, Brautigan, David L, Larner, James M
Published in PloS one (09.02.2009)
Published in PloS one (09.02.2009)
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Journal Article
Protein Phosphatase 6 Regulatory Subunits Composed of Ankyrin Repeat Domains
Stefansson, Bjarki, Ohama, Takashi, Daugherty, Abbi E, Brautigan, David L
Published in Biochemistry (Easton) (05.02.2008)
Published in Biochemistry (Easton) (05.02.2008)
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Modulation of NKG2D, NKp46, and Ly49C/I facilitates natural killer cell-mediated control of lung cancer
Shi, Lei, Li, Kang, Guo, Yizhan, Banerjee, Anirban, Wang, Qing, Lorenz, Ulrike M., Parlak, Mahmut, Sullivan, Lucy C., Onyema, Oscar Okwudiri, Arefanian, Saeed, Stelow, Edward B., Brautigan, David L., Bullock, Timothy N. J., Brown, Michael G., Krupnick, Alexander Sasha
Published in Proceedings of the National Academy of Sciences - PNAS (13.11.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (13.11.2018)
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The α4 Regulatory Subunit Exerts Opposing Allosteric Effects on Protein Phosphatases PP6 and PP2A
Prickett, Todd D., Brautigan, David L.
Published in The Journal of biological chemistry (13.10.2006)
Published in The Journal of biological chemistry (13.10.2006)
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Deletion of the SAPS1 subunit of protein phosphatase 6 in mice increases radiosensitivity and impairs the cellular DNA damage response
Dziegielewski, Jaroslaw, Bońkowska, Magdalena A., Poniecka, Ewa A., Heo, Jinho, Du, Kangping, Crittenden, Rowena B., Bender, Timothy P., Brautigan, David L., Larner, James M.
Published in DNA repair (01.01.2020)
Published in DNA repair (01.01.2020)
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Journal Article
The Phosphatase Ptc7 Induces Coenzyme Q Biosynthesis by Activating the Hydroxylase Coq7 in Yeast
Martín-Montalvo, Alejandro, González-Mariscal, Isabel, Pomares-Viciana, Teresa, Padilla-López, Sergio, Ballesteros, Manuel, Vazquez-Fonseca, Luis, Gandolfo, Pablo, Brautigan, David L., Navas, Placido, Santos-Ocaña, Carlos
Published in The Journal of biological chemistry (27.09.2013)
Published in The Journal of biological chemistry (27.09.2013)
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Journal Article
Phosphorylation of RalB Is Important for Bladder Cancer Cell Growth and Metastasis
HONG WANG, OWENS, Charles, CHANDRA, Nidhi, CONAWAY, Mark R, BRAUTIGAN, David L, THEODORESCU, Dan
Published in Cancer research (Chicago, Ill.) (01.11.2010)
Published in Cancer research (Chicago, Ill.) (01.11.2010)
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An Epilepsy-Associated CILK1 Variant Compromises KATNIP Regulation and Impairs Primary Cilia and Hedgehog Signaling
Limerick, Ana, McCabe, Ellie A, Turner, Jacob S, Kuang, Kevin W, Brautigan, David L, Hao, Yi, Chu, Cheuk Ying, Fu, Sean H, Ahmadi, Sean, Xu, Wenhao, Fu, Zheng
Published in Cells (Basel, Switzerland) (01.08.2024)
Published in Cells (Basel, Switzerland) (01.08.2024)
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Journal Article
Protein Phosphatase 6 Down-regulates TAK1 Kinase Activation in the IL-1 Signaling Pathway
Kajino, Taisuke, Ren, Hong, Iemura, Shun-ichiro, Natsume, Tohru, Stefansson, Bjarki, Brautigan, David L., Matsumoto, Kunihiro, Ninomiya-Tsuji, Jun
Published in The Journal of biological chemistry (29.12.2006)
Published in The Journal of biological chemistry (29.12.2006)
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