Ubiquitin-Induced Oligomerization of the RNA Sensors RIG-I and MDA5 Activates Antiviral Innate Immune Response
Jiang, Xiaomo, Kinch, Lisa N., Brautigam, Chad A., Chen, Xiang, Du, Fenghe, Grishin, Nick V., Chen, Zhijian J.
Published in Immunity (Cambridge, Mass.) (29.06.2012)
Published in Immunity (Cambridge, Mass.) (29.06.2012)
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Journal Article
The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop
Zhang, Xu, Wu, Jiaxi, Du, Fenghe, Xu, Hui, Sun, Lijun, Chen, Zhe, Brautigam, Chad A., Zhang, Xuewu, Chen, Zhijian J.
Published in Cell reports (Cambridge) (13.02.2014)
Published in Cell reports (Cambridge) (13.02.2014)
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Journal Article
Requirements for Efficient Correction of ΔF508 CFTR Revealed by Analyses of Evolved Sequences
Mendoza, Juan L., Schmidt, André, Li, Qin, Nuvaga, Emmanuel, Barrett, Tyler, Bridges, Robert J., Feranchak, Andrew P., Brautigam, Chad A., Thomas, Philip J.
Published in Cell (20.01.2012)
Published in Cell (20.01.2012)
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Journal Article
A TOG: alpha beta -tubulin Complex Structure Reveals Conformation-Based Mechanisms for a Microtubule Polymerase
Ayaz, Pelin, Ye, Xuecheng, Huddleston, Patrick, Brautigam, Chad A, Rice, Luke M
Published in Science (American Association for the Advancement of Science) (17.08.2012)
Published in Science (American Association for the Advancement of Science) (17.08.2012)
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Journal Article
A TOG:αβ-tubulin Complex Structure Reveals Conformation-Based Mechanisms for a Microtubule Polymerase
Ayaz, Pelin, Ye, Xuecheng, Huddleston, Patrick, Brautigam, Chad A., Rice, Luke M.
Published in Science (American Association for the Advancement of Science) (17.08.2012)
Published in Science (American Association for the Advancement of Science) (17.08.2012)
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Journal Article
On the acquisition and analysis of microscale thermophoresis data
Scheuermann, Thomas H., Padrick, Shae B., Gardner, Kevin H., Brautigam, Chad A.
Published in Analytical biochemistry (01.03.2016)
Published in Analytical biochemistry (01.03.2016)
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Journal Article
SAV1 promotes Hippo kinase activation through antagonizing the PP2A phosphatase STRIPAK
Bae, Sung Jun, Ni, Lisheng, Osinski, Adam, Tomchick, Diana R, Brautigam, Chad A, Luo, Xuelian
Published in eLife (24.10.2017)
Published in eLife (24.10.2017)
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Journal Article
Rac1 GTPase activates the WAVE regulatory complex through two distinct binding sites
Chen, Baoyu, Chou, Hui-Ting, Brautigam, Chad A, Xing, Wenmin, Yang, Sheng, Henry, Lisa, Doolittle, Lynda K, Walz, Thomas, Rosen, Michael K
Published in eLife (26.09.2017)
Published in eLife (26.09.2017)
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Journal Article
Structural Basis for Autoactivation of Human Mst2 Kinase and Its Regulation by RASSF5
Ni, Lisheng, Li, Sheng, Yu, Jianzhong, Min, Jungki, Brautigam, Chad A., Tomchick, Diana R., Pan, Duojia, Luo, Xuelian
Published in Structure (London) (08.10.2013)
Published in Structure (London) (08.10.2013)
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Journal Article
Structural basis of arrestin-3 activation and signaling
Chen, Qiuyan, Perry, Nicole A, Vishnivetskiy, Sergey A, Berndt, Sandra, Gilbert, Nathaniel C, Zhuo, Ya, Singh, Prashant K, Tholen, Jonas, Ohi, Melanie D, Gurevich, Eugenia V, Brautigam, Chad A, Klug, Candice S, Gurevich, Vsevolod V, Iverson, T M
Published in Nature communications (10.11.2017)
Published in Nature communications (10.11.2017)
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Journal Article
Mechanism of karyopherin-β2 binding and nuclear import of ALS variants FUS(P525L) and FUS(R495X)
Gonzalez, Abner, Mannen, Taro, Çağatay, Tolga, Fujiwara, Ayano, Matsumura, Hiroyoshi, Niesman, Ashley B, Brautigam, Chad A, Chook, Yuh Min, Yoshizawa, Takuya
Published in Scientific reports (12.02.2021)
Published in Scientific reports (12.02.2021)
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Journal Article
Structure and ligand-binding mechanism of the human OX1 and OX2 orexin receptors
Yin, Jie, Babaoglu, Kerim, Brautigam, Chad A, Clark, Lindsay, Shao, Zhenhua, Scheuermann, Thomas H, Harrell, Charles M, Gotter, Anthony L, Roecker, Anthony J, Winrow, Christopher J, Renger, John J, Coleman, Paul J, Rosenbaum, Daniel M
Published in Nature structural & molecular biology (01.04.2016)
Published in Nature structural & molecular biology (01.04.2016)
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