Coordinated Splicing of Regulatory Detained Introns within Oncogenic Transcripts Creates an Exploitable Vulnerability in Malignant Glioma
Braun, Christian J., Stanciu, Monica, Boutz, Paul L., Patterson, Jesse C., Calligaris, David, Higuchi, Fumi, Neupane, Rachit, Fenoglio, Silvia, Cahill, Daniel P., Wakimoto, Hiroaki, Agar, Nathalie Y.R., Yaffe, Michael B., Sharp, Phillip A., Hemann, Michael T., Lees, Jacqueline A.
Published in Cancer cell (09.10.2017)
Published in Cancer cell (09.10.2017)
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Journal Article
Sensitizing Protective Tumor Microenvironments to Antibody-Mediated Therapy
Pallasch, Christian P., Leskov, Ilya, Braun, Christian J., Vorholt, Daniela, Drake, Adam, Soto-Feliciano, Yadira M., Bent, Eric H., Schwamb, Janine, Iliopoulou, Bettina, Kutsch, Nadine, van Rooijen, Nico, Frenzel, Lukas P., Wendtner, Clemens M., Heukamp, Lukas, Kreuzer, Karl Anton, Hallek, Michael, Chen, Jianzhu, Hemann, Michael T.
Published in Cell (30.01.2014)
Published in Cell (30.01.2014)
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Journal Article
P53-Responsive MicroRNAs 192 and 215 Are Capable of Inducing Cell Cycle Arrest
BRAUN, Christian J, XIN ZHANG, SAVELYEVA, Irina, WOLFF, Sonja, MOLL, Ute M, SCHEPELER, Troels, ORNTOFT, Torben F, ANDERSEN, Claus L, DOBBELSTEIN, Matthias
Published in Cancer research (Chicago, Ill.) (15.12.2008)
Published in Cancer research (Chicago, Ill.) (15.12.2008)
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Journal Article
Versatile in vivo regulation of tumor phenotypes by dCas9-mediated transcriptional perturbation
Braun, Christian J., Bruno, Peter M., Horlbeck, Max A., Gilbert, Luke A., Weissman, Jonathan S., Hemann, Michael T.
Published in Proceedings of the National Academy of Sciences - PNAS (05.07.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (05.07.2016)
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Journal Article
Simultaneous screening of overexpressed genes in breast cancer for oncogenic drivers and tumor dependencies
Mofunanya, Adaobi, Cameron, Eleanor R, Braun, Christian J, Celeste, Frank, Zhao, Xiaoyu, Hemann, Michael T, Scott, Kenneth L, Li, Jinyu, Powers, Scott
Published in Scientific reports (09.06.2024)
Published in Scientific reports (09.06.2024)
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Journal Article
Loss-of-function mutations in the IL-21 receptor gene cause a primary immunodeficiency syndrome
Kotlarz, Daniel, Ziętara, Natalia, Uzel, Gulbu, Weidemann, Thomas, Braun, Christian J, Diestelhorst, Jana, Krawitz, Peter M, Robinson, Peter N, Hecht, Jochen, Puchałka, Jacek, Gertz, E Michael, Schäffer, Alejandro A, Lawrence, Monica G, Kardava, Lela, Pfeifer, Dietmar, Baumann, Ulrich, Pfister, Eva-Doreen, Hanson, Eric P, Schambach, Axel, Jacobs, Roland, Kreipe, Hans, Moir, Susan, Milner, Joshua D, Schwille, Petra, Mundlos, Stefan, Klein, Christoph
Published in The Journal of experimental medicine (11.03.2013)
Published in The Journal of experimental medicine (11.03.2013)
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Journal Article
A Pleiotropic RNA-Binding Protein Controls Distinct Cell Cycle Checkpoints to Drive Resistance of p53-Defective Tumors to Chemotherapy
Cannell, Ian G., Merrick, Karl A., Morandell, Sandra, Zhu, Chang-Qi, Braun, Christian J., Grant, Robert A., Cameron, Eleanor R., Tsao, Ming-Sound, Hemann, Michael T., Yaffe, Michael B.
Published in Cancer cell (09.11.2015)
Published in Cancer cell (09.11.2015)
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Journal Article
A role for PVRL4-driven cell-cell interactions in tumorigenesis
Pavlova, Natalya N, Pallasch, Christian, Elia, Andrew E H, Braun, Christian J, Westbrook, Thomas F, Hemann, Michael, Elledge, Stephen J
Published in eLife (30.04.2013)
Published in eLife (30.04.2013)
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Journal Article
In vivo functional screening for systems-level integrative cancer genomics
Weber, Julia, Braun, Christian J, Saur, Dieter, Rad, Roland
Published in Nature reviews. Cancer (01.10.2020)
Published in Nature reviews. Cancer (01.10.2020)
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Journal Article
Epigenetic drug screening defines a PRMT5 inhibitor-sensitive pancreatic cancer subtype
Orben, Felix, Lankes, Katharina, Schneeweis, Christian, Hassan, Zonera, Jakubowsky, Hannah, Krauß, Lukas, Boniolo, Fabio, Schneider, Carolin, Schäfer, Arlett, Murr, Janine, Schlag, Christoph, Kong, Bo, Öllinger, Rupert, Wang, Chengdong, Beyer, Georg, Mahajan, Ujjwal M, Xue, Yonggan, Mayerle, Julia, Schmid, Roland M, Kuster, Bernhard, Rad, Roland, Braun, Christian J, Wirth, Matthias, Reichert, Maximilian, Saur, Dieter, Schneider, Günter
Published in JCI insight (23.05.2022)
Published in JCI insight (23.05.2022)
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Journal Article
Tutorial: design and execution of CRISPR in vivo screens
Braun, Christian J., Adames, Andrés Carbonell, Saur, Dieter, Rad, Roland
Published in Nature protocols (01.09.2022)
Published in Nature protocols (01.09.2022)
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Journal Article
Minor Changes in Expression of the Mismatch Repair Protein MSH2 Exert a Major Impact on Glioblastoma Response to Temozolomide
McFaline-Figueroa, José L, Braun, Christian J, Stanciu, Monica, Nagel, Zachary D, Mazzucato, Patrizia, Sangaraju, Dewakar, Cerniauskas, Edvinas, Barford, Kelly, Vargas, Amanda, Chen, Yimin, Tretyakova, Natalia, Lees, Jacqueline A, Hemann, Michael T, White, Forest M, Samson, Leona D
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Journal Article
CRISPR somatic genome engineering and cancer modeling in the mouse pancreas and liver
Kaltenbacher, Thorsten, Löprich, Jessica, Maresch, Roman, Weber, Julia, Müller, Sebastian, Oellinger, Rupert, Groß, Nina, Griger, Joscha, de Andrade Krätzig, Niklas, Avramopoulos, Petros, Ramanujam, Deepak, Brummer, Sabine, Widholz, Sebastian A, Bärthel, Stefanie, Falcomatà, Chiara, Pfaus, Anja, Alnatsha, Ahmed, Mayerle, Julia, Schmidt-Supprian, Marc, Reichert, Maximilian, Schneider, Günter, Ehmer, Ursula, Braun, Christian J, Saur, Dieter, Engelhardt, Stefan, Rad, Roland
Published in Nature protocols (01.04.2022)
Published in Nature protocols (01.04.2022)
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Journal Article
Pseudo painting/air bubble technique for planar lipid bilayers
Braun, Christian J., Baer, Tom, Moroni, Anna, Thiel, Gerhard
Published in Journal of neuroscience methods (15.08.2014)
Published in Journal of neuroscience methods (15.08.2014)
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Journal Article
Publisher Correction: Comprehensive genomic characterization of gene therapy-induced T-cell acute lymphoblastic leukemia
Horak, Peter, Uhrig, Sebastian, Witzel, Maximilian, Gil-Farina, Irene, Hutter, Barbara, Rath, Tim, Gieldon, Laura, Balasubramanian, Gnana Prakash, Pastor, Xavier, Heilig, Christoph E, Richter, Daniela, Schröck, Evelin, Ball, Claudia R, Brors, Benedikt, Braun, Christian J, Albert, Michael H, Scholl, Claudia, von Kalle, Christof, Schmidt, Manfred, Fröhling, Stefan, Klein, Christoph, Glimm, Hanno
Published in Leukemia (01.12.2021)
Published in Leukemia (01.12.2021)
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Journal Article
Comprehensive genomic characterization of gene therapy-induced T-cell acute lymphoblastic leukemia
Horak, Peter, Uhrig, Sebastian, Witzel, Maximilian, Gil-Farina, Irene, Hutter, Barbara, Rath, Tim, Gieldon, Laura, Balasubramanian, Gnana Prakash, Pastor, Xavier, Heilig, Christoph E, Richter, Daniela, Schröck, Evelin, Ball, Claudia R, Brors, Benedikt, Braun, Christian J, Albert, Michael H, Scholl, Claudia, von Kalle, Christof, Schmidt, Manfred, Fröhling, Stefan, Klein, Christoph, Glimm, Hanno
Published in Leukemia (01.10.2020)
Published in Leukemia (01.10.2020)
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Journal Article
A Raf-Competitive K-Ras Binder Can Fail to Functionally Antagonize Signaling
Kauke, Monique J, Tisdale, Alison W, Kelly, Ryan L, Braun, Christian J, Hemann, Michael T, Wittrup, K Dane
Published in Molecular cancer therapeutics (01.08.2018)
Published in Molecular cancer therapeutics (01.08.2018)
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Journal Article